Morphine-6-glucuronide, a potent mu agonist

Life Sciences

Volumn 41, Issue 26, 1987, Pages 2845-2849

  Pasternak, Gavril W ^a,b   Bodnar, Richard J ^a,c   Clark, Janet A ^a   Inturrisi, Charles E ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENKEPHALIN DERIVATIVE H 3; ETHYLKETAZOCINE H 3; MORPHINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 GLUCURONIDE; NALOXONE; OPIATE RECEPTOR; RADIOISOTOPE; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL EXPERIMENT; DRUG METABOLISM; DRUG RECEPTOR BINDING; NONHUMAN; PHARMACOKINETICS; PRELIMINARY COMMUNICATION; RAT;

ANIMAL; BIOTRANSFORMATION; MALE; MICROINJECTIONS; MORPHINE; MORPHINE DERIVATIVES; RATS; RATS, INBRED STRAINS; RECEPTORS, OPIOID; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023620266     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/0024-3205(87)90431-0     Document Type: Article

References (16)

1. Biochemical basis for analgesic activity of morphine-6-glucuronide—I
2. The irreversible narcotic antagonistic and reversible agonistic properties of the fumaramate methyl ester derivative of naltrexone