Efficacy of a combination of acetylcholinesterase reactivators, HI-6 and obidoxime, against tabun and soman poisoning of mice

Archives of Toxicology

Volumn 61, Issue 1, 1987, Pages 70-75

  Clement, John G ^a   Shiloff, J Deborah ^a   Gennings, Chris ^b  

^a CFB Suffield   (Canada)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Bispyridinium; HI 6 1 ((((4 aminocarbonyl) pyridinio metho xy methyl) 2 ((hydroxyimino) methyl)pyrindium dichloride; Obidoxime 1,1 (oxy bis(methylene))bis(4 hydroxyimino) methyl) pyridinium dibromide; Oximes; Reactivation; Soman (pinacolyl methylphosphonofluoridate); Tabun (ethyl N dime thylphosphoramidocyanidate)

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; ACETYLCHOLINESTERASE; ATROPINE; OBIDOXIME; SOMAN; TABUN;

ANIMAL EXPERIMENT; BLOOD AND HEMOPOIETIC SYSTEM; DRUG EFFICACY; DRUG HALF LIFE; DRUG MECHANISM; DRUG MIXTURE; ENZYME REACTIVATION; INTOXICATION; INTRAPERITONEAL DRUG ADMINISTRATION; KIDNEY; MOUSE; NEPHROTOXICITY; NONHUMAN; PHARMACOKINETICS; SUBCUTANEOUS DRUG ADMINISTRATION; THERAPY;

ACETYLCHOLINESTERASE; ANIMAL; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; DRUG THERAPY, COMBINATION; MALE; MICE; OBIDOXIME CHLORIDE; ORGANOPHOSPHORUS COMPOUNDS; OXIMES; PHOSPHORIC ACID ESTERS; PYRIDINIUM COMPOUNDS; SOMAN;

EID: 0023615814     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/BF00324551     Document Type: Article

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