A comparison of the Two One-Sided Tests Procedure and the Power Approach for assessing the equivalence of average bioavailability

Journal of Pharmacokinetics and Biopharmaceutics

Volumn 15, Issue 6, 1987, Pages 657-680

  Schuirmann, Donald J ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

bioavailability; bioequivalence; hypothesis testing; interval hypotheses

Indexed keywords

DRUG BIOAVAILABILITY; METHODOLOGY; NONHUMAN; POWER; STATISTICS;

BIOLOGICAL AVAILABILITY; MODELS, BIOLOGICAL; PHARMACOKINETICS; STATISTICS;

EID: 0023615056     PISSN: 0090466X     EISSN: 15738744     Source Type: Journal    
DOI: 10.1007/BF01068419     Document Type: Article

References (7)

1. A new statistical procedure for testing equivalence in two-group comparative bioavailability trials
2. Response to T. B. L. Kirkwood: Bioequivalence testing-a need to rethink
3. A new procedure for testing equivalence in comparative bioavailability and other clinical trials
4. On testing for bioequivalence
5. The design and analysis of comparative blood-level trials
6. Comparison of different methods for decision-making in bio-equivalence assessment
7. An exact confidence interval from untransformed data for the ratio of two formulation means