Complete cloning of the duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals

Cell

Volumn 50, Issue 3, 1987, Pages 509-517

  Koenig, M ^a   Hoffman, E P ^a   Bertelson, C J ^a   Monaco, A P ^b   Feener, C ^c   Kunkel, L M ^c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD UNIVERSITY   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONTROLLED STUDY; DUCHENNE MUSCULAR DYSTROPHY; GENETIC ENGINEERING; HUMAN; HUMAN CELL;

AMINO ACID SEQUENCE; BASE SEQUENCE; CHROMOSOME DELETION; CHROMOSOME MAPPING; CLONING, MOLECULAR; DNA; GENE EXPRESSION REGULATION; HUMAN; MUSCULAR DYSTROPHIES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023614271     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(87)90504-6     Document Type: Article

References (43)

1. A strategy to reveal high-frequency RFLPs along the human X chromosome
2. Prenatal diagnosis and carrier detection of Duchenne muscular dystrophy with closely linked RFLPs
3. Screening lambda gt recombinants clones by hybridization to single plaques in situ
4. Muscular dystrophy in girls with X-autosome translocations
5. Isolation of a cDNA clone from the region of an X21 translocation that breaks within the Duchenne/Becker muscular dystrophy gene
6. Long-range restriction map around the Duchenne muscular dystrophy gene
7. Prenatal diagnosis and detection of carriers with DNA probes in Duchenne's muscular dystrophy
8. Linkage analysis of two cloned DNA sequences flanking the Duchenne muscular dystrophy tocus on the short arm of the human X chromosome
9. Recombination with pERT87 (DXS164) in families with X-linked muscular dystrophy
10. Minor Xp21 chromosome deletion in a male associated with expression of Duchenne muscular dystrophy, chronic granulomatous disease, retinitis pigmentosa and McLeod syndrome
11. Fertility in patients with X-chromosome deletions
12. Deletion of a DNA sequence in eight of nine families with X-linked ichthyosis (steroid sulfatase deficiency)
13. Report of the committee on the genetic constitution of the X and Y chromosomes
14. An X-autosome translocation in a girl with Duchenne muscular dystrophy evidence for DMD gene localisation
15. A simple and very efficient method for generating cDNA libraries
16. Conservation of the Duchenne muscular dystrophy gene in mice and humans
17. Constructing and screening cDNA libraries in lambda gt10 and gt11
18. Molecular analysis of the Duchenne muscular dystrophy region using pulsed field gel electrophoresis
19. Localization of the gene for Becker muscular dystrophy
20. Regional localization on the human X of DNA segments cloned from flow sorted chromosomes
21. Specific cloning of DNA fragments absent from the DNA of a male patient with an X-chromosome deletion
22. Analysis of deletions in DNA of patients with Becker and Duchenne muscular dystrophy
23. Sequencing end-labeled DNA with base-specific chemical cleavages
24. Expression of an X-linked gene from an inactive human X chromosome in mouse-human hybird cells: further evidence for the non-inactivation of the steroid sulfatase locus in man
25. A giant locus for the Duchenne and Becker muscular dystrophy gene
26. Detection of deletions spanning the Duchenne muscular dystrophy locus using a tightly linked DNA segment
27. Isolation of candidate cDNAs for portions of the Duchenne muscular dystrophy gene
28. Localization and cloning of Xp21 deletion breakpoints involved in muscular dystrophy
29. Duchenne muscular dystrophy: pathogenic aspects and genetic prevention
30. Mutation and polymorphism of the human beta-globin gene and its surrounding DNA
31. 3′ non-coding region sequences in eukaryotic mRNA
32. Cloning of the breakpoint of an X:21 translocation associated with Duchenne muscular dystrophy
33. Gene deletion and restriction fragment length polymorphisms at the human ornithine transcarbarmylase locus
34. DNA sequencing with chain-terminating inhibitors
35. Complete nucleotide and encoded amino acid sequence of a mammalian myosin heavy chain gene
36. A physical map of 4 million bp around the Duchenne muscular dystrophy gene on the human X chromosome
37. Expression of an X-linked muscular dystrophy in a female due to translocation involving Xp21 and non-random X-inactivation
38. Duchenne muscular dystrophy involving translocation of the DMD gene next to ribosomal DNA genes
39. Molecular evidence for new mutation at the HPRT locus in Lesch-Nyhan patients
40. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and PUC19 vectors
41. Cloning and expression of steroid sulfatase cDNA and the frequent occurrence of deletions of STS deficiency implications for X-Y interchange
42. Characterization of five partial deletions of the factor VIII gene
43. Translocation (X,6) in a female with Duchenne muscular dystrophy, implications for the localisation of the DMD locus