Cytogenetic damage induced in human lymphocytes by adriamycin and vincristine: A comparison between micronucleus and chromosomal aberration assays

Toxicology in Vitro

Volumn 1, Issue 4, 1987, Pages 247-254

  Migliore, L ^a   Barale, R ^a   Belluomini, D ^a   Cognetti, A G ^a   Loprieno, N ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHALASIN B; DOXORUBICIN; VINCRISTINE;

CHROMOSOME ABERRATION; HEREDITY; HUMAN; HUMAN CELL; METHODOLOGY; MICRONUCLEUS TEST; MUTAGENICITY;

EID: 0023575396     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/0887-2333(87)90027-0     Document Type: Article

References (17)

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3. Micronucleus test in cytokinesis-blocked (CB) human lymphocytes as a new approach for biological dosimetry
4. The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes
5. Radiation induced micronuclei possess kinetochores
6. Measurement of micronuclei in lymphocytes
7. Cytokinesis-block micronucleus method in human lymphocytes: effect of in vivo ageing and low dose X-irradiation
8. The induction of micronuclei as a measure of genotoxicity. A Report of the U.S. Environmental Protection Agency Gene-Tox Program
9. Micronuclei in lymphocytes with preserved cytoplasm A method for assessment of cytogenetic damage in man
10. Chromosome aberrations and micronuclei in bone marrow cells and peripheral blood lymphocytes in humans exposed to ethylene oxide
11. The size of micronuclei in human lymphocytes varies according to inducing agent used
12. The suitability of the human lymphocyte micronucleus assay system for biological dosimetry
13. 1 by metabolic activation with rat-liver microsomes on human lymphocytes assayed with the micronucleus test
14. Micronuclei as a rapid and inexpensive measure of radiation-induced chromosomal aberration
15. An improved micronuclear assay in lymphocytes
16. Differential Giemsa staining of sister chromatid exchanges without autoradiography
17. A comparison of diameters of micronuclei induced by clastogens and by spindle poisons