메뉴 건너뛰기




Volumn 317, Issue 27, 1987, Pages 1692-1698

Ceftazidime Combined with a Short or Long Course of Amikacin for Empirical Therapy of Gram-Negative Bacteremia in Cancer Patients with Granulocytopenia

(1)  Calandra, Thierry a  

a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AZLOCILLIN; CEFTAZIDIME;

EID: 0023551772     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM198712313172703     Document Type: Article
Times cited : (366)

References (32)
  • 1
    • 0015221860 scopus 로고
    • Empiric therapy with carbenicillin and gentamicin for febrile patients with cancer and granulocytopenia
    • Schimpff S, Satterlee W, Young VM, Serpick A. Empiric therapy with carbenicillin and gentamicin for febrile patients with cancer and granulocytopenia. N Engl J Med 1971; 284: 1061–5.
    • (1971) N Engl J Med , vol.284 , pp. 1061-1065
    • Schimpff, S.1    Satterlee, W.2    Young, V.M.3    Serpick, A.4
  • 2
    • 84910576751 scopus 로고
    • Empiric therapy and prevention of infection in the immunocompromised host
    • In: Mandell GL, Douglas RG Jr, Bennett JE, eds. Principles and practice of infectious diseases. 2nd ed. New York: John Wiley
    • Pizzo PA. Empiric therapy and prevention of infection in the immunocompromised host. In: Mandell GL, Douglas RG Jr, Bennett JE, eds. Principles and practice of infectious diseases. 2nd ed. New York: John Wiley, 1985:1680–8.
    • (1985) , pp. 1680-1688
    • Pizzo, P.A.1
  • 3
    • 0017797799 scopus 로고
    • Three antibiotic regimens in the treatment of infection in febrile granulocytopenic patients with cancer
    • The EORTC International Antimicrobial Therapy Project Group. Three antibiotic regimens in the treatment of infection in febrile granulocytopenic patients with cancer. J Infect Dis 1978; 137: 14–29.
    • (1978) J Infect Dis , vol.137 , pp. 14-29
  • 4
    • 0021064296 scopus 로고
    • Combination of amikacin and carbenicillin with or without cefazolin as empirical treatment of febrile neutropenic patients
    • The International Antimicrobial Therapy Project Group of the European Organization for Research and Treatment of Cancer. Combination of amikacin and carbenicillin with or without cefazolin as empirical treatment of febrile neutropenic patients. J Clin Oncol 1983; 1: 597–603.
    • (1983) J Clin Oncol , vol.1 , pp. 597-603
  • 5
    • 0022617285 scopus 로고
    • European Organization for Research on Treatment of Cancer Antimicrobial Therapy Project Group. Prospective randomized comparison of three antibiotic regimens for empirical therapy of suspected bacteremic infection in febrile granulocytopenic patients
    • Klastersky J, Glauser MP, Schimpff SC, Zinner SH, Gaya H. European Organization for Research on Treatment of Cancer Antimicrobial Therapy Project Group. Prospective randomized comparison of three antibiotic regimens for empirical therapy of suspected bacteremic infection in febrile granulocytopenic patients. Antimicrob Agents Chemother 1986; 29: 263–70.
    • (1986) Antimicrob Agents Chemother , vol.29 , pp. 263-270
    • Klastersky, J.1    Glauser, M.P.2    Schimpff, S.C.3    Zinner, S.H.4    Gaya, H.5
  • 6
    • 2342636972 scopus 로고
    • Empiric carbenicillin, gentamicin and cephalothin therapy for presumed infection in patients with granulocytopenia and cancer
    • abstract.
    • Greene WH, Schimpff SC, Young VM, Wiernik PH. Empiric carbenicillin, gentamicin and cephalothin therapy for presumed infection in patients with granulocytopenia and cancer. Ann Intern Med 1973; 78: 825–6. abstract.
    • (1973) Ann Intern Med , vol.78 , pp. 825-826
    • Greene, W.H.1    Schimpff, S.C.2    Young, V.M.3    Wiernik, P.H.4
  • 7
    • 0017802325 scopus 로고
    • Granulocytopenia in hospitalized patients. II. A prospective comparison of two antibiotic regimens in the empiric therapy of febrile patients
    • Gurwith M, Brunton JL, Lank B, Ronald AR, Harding GKM, McCullough DW. Granulocytopenia in hospitalized patients. II. A prospective comparison of two antibiotic regimens in the empiric therapy of febrile patients. Am J Med 1978; 64: 127–32.
    • (1978) Am J Med , vol.64 , pp. 127-132
    • Gurwith, M.1    Brunton, J.L.2    Lank, B.3    Ronald, A.R.4    Harding, G.K.M.5    McCullough, D.W.6
  • 8
    • 0018416060 scopus 로고
    • A randomized comparative trial of three aminoglycosides — comparison of continuous infusions of gentamicin, amikacin and sisomicin combined with carbenicillin in the treatment of infections in neutropenic patients with malignancies
    • Keating MJ, Bodey GP, Valdivieso M, Rodriguez V. A randomized comparative trial of three aminoglycosides — comparison of continuous infusions of gentamicin, amikacin and sisomicin combined with carbenicillin in the treatment of infections in neutropenic patients with malignancies. Medicine (Baltimore) 1979; 58: 159–70.
    • (1979) Medicine (Baltimore) , vol.58 , pp. 159-170
    • Keating, M.J.1    Bodey, G.P.2    Valdivieso, M.3    Rodriguez, V.4
  • 9
    • 0018763773 scopus 로고
    • Randomized trial of empiric antibiotic therapy with ticarcillin in combination with gentamicin, amikacin or netilmicin in febrile patients with granulocytopenia and cancer
    • Love LJ, Schimpff SC, Hahn DM, et al. Randomized trial of empiric antibiotic therapy with ticarcillin in combination with gentamicin, amikacin or netilmicin in febrile patients with granulocytopenia and cancer. Am J Med 1979; 66: 603–10.
    • (1979) Am J Med , vol.66 , pp. 603-610
    • Love, L.J.1    Schimpff, S.C.2    Hahn, D.M.3
  • 10
    • 0019805914 scopus 로고
    • Piperacillin or ticarcillin plus amikacin: a double-blind prospective comparison of empiric antibiotic therapy for febrile granulocytopenic cancer patients
    • Wade JC, Schimpff SC, Newman KA, Fortner CL, Standiford HC, Wiernik PH. Piperacillin or ticarcillin plus amikacin: a double-blind prospective comparison of empiric antibiotic therapy for febrile granulocytopenic cancer patients. Am J Med 1981; 71: 983–90.
    • (1981) Am J Med , vol.71 , pp. 983-990
    • Wade, J.C.1    Schimpff, S.C.2    Newman, K.A.3    Fortner, C.L.4    Standiford, H.C.5    Wiernik, P.H.6
  • 11
    • 84948724874 scopus 로고
    • Piperacillin plus amikacin therapy v. carbenicillin plus amikacin therapy in febrile, granulocytopenic patients
    • Winston DJ, Ho WG, Young LS, Hewitt WL, Gale RP. Piperacillin plus amikacin therapy v. carbenicillin plus amikacin therapy in febrile, granulocytopenic patients. Arch Intern Med 1982; 142: 1663–7.
    • (1982) Arch Intern Med , vol.142 , pp. 1663-1667
    • Winston, D.J.1    Ho, W.G.2    Young, L.S.3    Hewitt, W.L.4    Gale, R.P.5
  • 12
    • 84879282563 scopus 로고
    • Empiric antibiotic therapy for suspected infection in granulocytopenic cancer patients: a comparison between the combination of moxalactam plus amikacin and ticarcillin plus amikacin
    • de Jongh CA, Wade JC, Schimpff SC, et al. Empiric antibiotic therapy for suspected infection in granulocytopenic cancer patients: a comparison between the combination of moxalactam plus amikacin and ticarcillin plus amikacin. Am J Med 1982; 73: 89–96.
    • (1982) Am J Med , vol.73 , pp. 89-96
    • de Jongh, C.A.1    Wade, J.C.2    Schimpff, S.C.3
  • 13
    • 0018664845 scopus 로고
    • A randomized study of carbenicillin plus cefamandole or tobramycin in the treatment of febrile episodes in cancer patients
    • Bodey GP, Ketchel SJ, Rodriguez V. A randomized study of carbenicillin plus cefamandole or tobramycin in the treatment of febrile episodes in cancer patients. Am J Med 1979; 67: 608–16.
    • (1979) Am J Med , vol.67 , pp. 608-616
    • Bodey, G.P.1    Ketchel, S.J.2    Rodriguez, V.3
  • 14
    • 0021271390 scopus 로고
    • Moxalactam plus piperacillin versus moxalactam plus amikacin in febrile granulocytopenic patients
    • Winston DJ, Barnes RC, Ho WG, Young LS, Champlin RE, Gale RP. Moxalactam plus piperacillin versus moxalactam plus amikacin in febrile granulocytopenic patients. Am J Med 1984; 77: 442–50.
    • (1984) Am J Med , vol.77 , pp. 442-450
    • Winston, D.J.1    Barnes, R.C.2    Ho, W.G.3    Young, L.S.4    Champlin, R.E.5    Gale, R.P.6
  • 15
    • 84941818290 scopus 로고
    • A multicenter comparative trial of tobramycin and ticarcillin vs moxalactam and ticarcillin in febrile neutropenic patients
    • Feld R, Louie TJ, Mandell L, et al. A multicenter comparative trial of tobramycin and ticarcillin vs moxalactam and ticarcillin in febrile neutropenic patients. Arch Intern Med 1985; 145: 1083–8.
    • (1985) Arch Intern Med , vol.145 , pp. 1083-1088
    • Feld, R.1    Louie, T.J.2    Mandell, L.3
  • 16
    • 0015484953 scopus 로고
    • Clinical significance of in vitro synergism between antibiotics in gram-negative infections
    • Klastersky J, Cappel R, Daneau D. Clinical significance of in vitro synergism between antibiotics in gram-negative infections. Antimicrob Agents Chemother 1972; 2: 470–5.
    • (1972) Antimicrob Agents Chemother , vol.2 , pp. 470-475
    • Klastersky, J.1    Cappel, R.2    Daneau, D.3
  • 17
    • 0017646537 scopus 로고
    • Significance of antimicrobial synergism for the outcome of gram negative sepsis
    • Klastersky J, Meunier-Carpentier F, Prevost J-M. Significance of antimicrobial synergism for the outcome of gram negative sepsis. Am J Med Sci 1977; 273: 157–67.
    • (1977) Am J Med Sci , vol.273 , pp. 157-167
    • Klastersky, J.1    Meunier-Carpentier, F.2    Prevost, J.-M.3
  • 18
    • 0017927868 scopus 로고
    • Antimicrobial synergism in the therapy of gram-negative rod bacteremia
    • Anderson ET, Young LS, Hewitt WL. Antimicrobial synergism in the therapy of gram-negative rod bacteremia. Chemotherapy 1978; 24: 45–54.
    • (1978) Chemotherapy , vol.24 , pp. 45-54
    • Anderson, E.T.1    Young, L.S.2    Hewitt, W.L.3
  • 19
    • 0021322096 scopus 로고
    • Significance of serum bactericidal activity in gram-negative bacillary bacteremia in patients with and without granulocytopenia
    • Sculier JP, Klastersky J. Significance of serum bactericidal activity in gram-negative bacillary bacteremia in patients with and without granulocytopenia. Am J Med 1984; 76: 429–35.
    • (1984) Am J Med , vol.76 , pp. 429-435
    • Sculier, J.P.1    Klastersky, J.2
  • 20
    • 0022575593 scopus 로고
    • Antibiotic synergism and response in gram-negative bacteremia in granulocytopenic cancer patients
    • de Jongh CA, Joshi JH, Newman KA, et al. Antibiotic synergism and response in gram-negative bacteremia in granulocytopenic cancer patients. Am J Med 1986; 80: Suppl 5C: 96–100.
    • (1986) Am J Med , vol.80 , pp. 96-100
    • de Jongh, C.A.1    Joshi, J.H.2    Newman, K.A.3
  • 21
    • 0018900642 scopus 로고
    • Improved prognosis for granulocytopenic patients with gram-negative bacteremia
    • Love LJ, Schimpff SC, Schiffer CA, Wiernik PH. Improved prognosis for granulocytopenic patients with gram-negative bacteremia. Am J Med 1980; 68: 643–8.
    • (1980) Am J Med , vol.68 , pp. 643-648
    • Love, L.J.1    Schimpff, S.C.2    Schiffer, C.A.3    Wiernik, P.H.4
  • 22
    • 0020515919 scopus 로고
    • Prospective randomized trial of piperacillin monotherapy versus earboxypenicillin-aminoglycoside combination regimens in the empirical treatment of serious bacterial infections
    • Gribble MJ, Chow AW, Naiman SC, et al. Prospective randomized trial of piperacillin monotherapy versus earboxypenicillin-aminoglycoside combination regimens in the empirical treatment of serious bacterial infections. Antimicrob Agents Chemother 1983; 24: 388–93.
    • (1983) Antimicrob Agents Chemother , vol.24 , pp. 388-393
    • Gribble, M.J.1    Chow, A.W.2    Naiman, S.C.3
  • 23
    • 0021822077 scopus 로고
    • Double β-lactam therapy in the immunocompromised host
    • Young LS. Double β-lactam therapy in the immunocompromised host. J Antimicrob Chemother 1985; 16: 4–6.
    • (1985) J Antimicrob Chemother , vol.16 , pp. 4-6
    • Young, L.S.1
  • 24
    • 0022622910 scopus 로고
    • Randomized comparison between two ceftazidime-containing regimens and cephalothin-gentamicin-carbenicillin in febrile granulocytopenic cancer patients
    • Kramer BS, Ramphal R, Rand KH. Randomized comparison between two ceftazidime-containing regimens and cephalothin-gentamicin-carbenicillin in febrile granulocytopenic cancer patients. Antimicrob Agents Chemother 1986; 30: 64–8.
    • (1986) Antimicrob Agents Chemother , vol.30 , pp. 64-68
    • Kramer, B.S.1    Ramphal, R.2    Rand, K.H.3
  • 25
    • 0020634374 scopus 로고
    • Randomized study of ceftazidime versus gentamicin plus cefotaxime for infections in severe granulocytopenic patients
    • de Pauw BE, Kauw F, Muytjens H, Williams KJ, Bothof T. Randomized study of ceftazidime versus gentamicin plus cefotaxime for infections in severe granulocytopenic patients. J Antimicrob Chemother 1983; 12: Suppl A: 93–9.
    • (1983) J Antimicrob Chemother , vol.12 , pp. 93-99
    • de Pauw, B.E.1    Kauw, F.2    Muytjens, H.3    Williams, K.J.4    Bothof, T.5
  • 26
    • 0020566630 scopus 로고
    • A randomized study of ceftazidime compared to ceftazidime and tobramycin for the treatment of infections in cancer patients
    • Fainstein V, Bodey GP, Elting L, et al. A randomized study of ceftazidime compared to ceftazidime and tobramycin for the treatment of infections in cancer patients. J Antimicrob Chemother 1983; 12: Suppl A: 101–10.
    • (1983) J Antimicrob Chemother , vol.12 , pp. 101-110
    • Fainstein, V.1    Bodey, G.P.2    Elting, L.3
  • 27
    • 0021678822 scopus 로고
    • Single-drug versus combination empirical therapy for gram-negative bacillary infections in febrile cancer patients with and without granulocytopenia
    • Piccart M, Klastersky J, Meunier F, Lagast H, Van Laethem Y, Weerts D. Single-drug versus combination empirical therapy for gram-negative bacillary infections in febrile cancer patients with and without granulocytopenia. Antimicrob Agents Chemother 1984; 26: 870–5.
    • (1984) Antimicrob Agents Chemother , vol.26 , pp. 870-875
    • Piccart, M.1    Klastersky, J.2    Meunier, F.3    Lagast, H.4    Van Laethem, Y.5    Weerts, D.6
  • 28
    • 0022409734 scopus 로고
    • A randomized prospective study of ceftazidime versus ceftazidime plus flucloxacillin in the empiric treatment of febrile episodes in severely neutropenic patients
    • de Pauw B, Williams K, de Neeff J, et al. A randomized prospective study of ceftazidime versus ceftazidime plus flucloxacillin in the empiric treatment of febrile episodes in severely neutropenic patients. Antimicrob Agents Chemother 1985; 28: 824–8.
    • (1985) Antimicrob Agents Chemother , vol.28 , pp. 824-828
    • de Pauw, B.1    Williams, K.2    de Neeff, J.3
  • 29
    • 0022547096 scopus 로고
    • A randomized trial comparing ceftazidime alone with combination antibiotic therapy in cancer patients with fever and neutropenia
    • Pizzo PA, Hathorn JW, Hiemenz J, et al. A randomized trial comparing ceftazidime alone with combination antibiotic therapy in cancer patients with fever and neutropenia. N Engl J Med 1986; 315: 552–8.
    • (1986) N Engl J Med , vol.315 , pp. 552-558
    • Pizzo, P.A.1    Hathorn, J.W.2    Hiemenz, J.3
  • 31
    • 0023098089 scopus 로고
    • Antibiotic therapy in cancer patients with fever and neutropenia
    • Kramer BS, Ramphal R, Rand K. Antibiotic therapy in cancer patients with fever and neutropenia. N Engl J Med 1987; 316: 410–1.
    • (1987) N Engl J Med , vol.316 , pp. 410-411
    • Kramer, B.S.1    Ramphal, R.2    Rand, K.3
  • 32
    • 0022528589 scopus 로고
    • Empirical antimicrobial therapy in the neutropenic host
    • Young LS. Empirical antimicrobial therapy in the neutropenic host. N Engl J Med 1986; 315: 580–1.
    • (1986) N Engl J Med , vol.315 , pp. 580-581
    • Young, L.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.