Improved immunogenicity of a peptide epitope after fusion to hepatitis B core protein

Nature

Volumn 330, Issue 6146, 1987, Pages 381-384

  Clarke, B E ^a   Newton, S E ^a,b   Carroll, A R ^a   Francis, M J ^a   Appleyard, G ^a   Syred, A D ^a   Highfield, P E ^a   Rowlands, D J ^a   Brown, F ^a  

^a Wellcome Biotechnology   (United Kingdom)

^b Veterinary Clinical Centre   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B CORE ANTIBODY; HEPATITIS B VACCINE;

IMMUNOGENICITY; NONHUMAN; VACCINATION;

ANIMAL; ANTIGENS, VIRAL; APHTHOVIRUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; ESCHERICHIA COLI; GENES, STRUCTURAL; GENES, VIRAL; GUINEA PIGS; HEPATITIS B CORE ANTIGENS; RECOMBINANT PROTEINS; TRANSCRIPTION, GENETIC; VACCINES, SYNTHETIC;

EID: 0023546339     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/330381a0     Document Type: Article

References (22)

1. Bittle, J. L. et al. Nature 298, 30-33 (1982).
2. Neurath, A. R., Jameson, B. A. & Huima, T. Microbiol. Sci. 4, 45-51 (1987).
3. Francis, M. J. et al. Immunology 61, 1-6 (1987).
4. Francis, M. J. et al. J. gen. Virol. 66, 2347-2354 (1985).
5. DiMarchi, R. et al. Science 232, 639-641 (1986).
6. Winther, M. D. et al. J. Immun. 136, 1835-1840 (1986).
7. Stahl, S. et al. Proc. natn. Acad. Sci. U.S.A. 79, 1606-1610 (1982).
8. Cohen, B. J. & Richmond, J. E. Nature 296, 677-678 (1982).
9. Takahashi, K. et al. J. Immun. 13, 2903-2908 (1983).
10. Pasek, M. et al. Nature 282, 575-579 (1979).
11. Ou, J-H., Laub, O. & Rutter, W. J. Proc. natn. Acad. Sci. U.S.A. 83, 1578-1582 (1986).
12. Roossinck, M. J. et al. Molec. cell Biol. 6, 1393-1400 (1986).
13. Uy, A. et al. Virology 155, 89-96 (1986).
14. McLachlan, A. et al. J. Virol. 61, 683-692 (1987).
15. Newton, S. E. et al. in Vaccines 86 (eds Brown, F., Chanock, R. M. & Lerner, R. A.) 303-309 (Cold Spring Harbor Laboratory, New York, 1986).
16. Delpeyroux, F. et al. Science 233, 472-475 (1986).
17. Broekhuijsen, M. et al. J. gen. Virol, (in the press).
18. Mackett, M., Smith, G. & Moss, B. in DNA Cloning: A Practical Approach Vol. 2 (ed. Glover, D. M.) 191 (IRL, Oxford, 1985).
19. Francis, M. J. & Black, L. J. Hyg. Camb. 91, 329-334 (1983).
20. Milich, D. R. & McLachlan, A. Science 234, 1398-1401 (1986).
21. Adams, S. E., Dawson K. M., Gull, K., Kingsman, S. & Kingsman, A. J. Nature 329, 68-70 (1987).
22. Milich, D. R., McLachlan, A., Thornton, G. & Hughes, J. L. Nature 329, 547-549 (1987).