Autoradiographic evidence of serotonin1 binding sites on primary afferent fibres in the dorsal horn of the rat spinal cord

Neuroscience Letters

Volumn 83, Issue 1-2, 1987, Pages 71-76

  Daval, Geneviève ^a   Vergé, Daniel ^a   Basbaum, Allan I ^b   Bourgoin, Sylvie ^c   Hamon, Michel ^c  

^a CNRS   (France)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Capsaicin; Dorsal rhizotomy; Opiate receptor; Quantitative autoradiography; Rat spinal cord; Serotonin receptor

Indexed keywords

CAPSAICIN; NALOXONE; OPIATE RECEPTOR; SEROTONIN RECEPTOR; TETRALIN; UNCLASSIFIED DRUG; SEROTONIN;

ANIMAL EXPERIMENT; AUTORADIOGRAPHY; MUSCLE SPINDLE AFFERENT NERVE; NONHUMAN; RAT; RHIZOTOMY; SPINAL CORD DORSAL HORN; ANIMAL; ARTICLE; BINDING SITE; DRUG EFFECT; MALE; METABOLISM; NERVE FIBER; RAT STRAIN; SENSORY NERVE; SPINAL CORD;

AFFERENT PATHWAYS; ANIMAL; AUTORADIOGRAPHY; BINDING SITES; CAPSAICIN; MALE; NERVE FIBERS; RATS; RATS, INBRED STRAINS; SEROTONIN; SPINAL CORD; SUPPORT, NON-U.S. GOV'T;

EID: 0023522750     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(87)90218-7     Document Type: Article

References (24)

1. Endogenous pain control systems: brain stem spinal pathways and endorphin circuitry
2. Effect of iontophoretically applied 5-hydroxytryptamine on the excitability of single primary afferent C- and A-fibres in the cat spinal cord
3. 3H]Tyr-d-Ser-Gly-Phe-Leu-Thr: a specific probe for the δ opiate receptor subtype in brain membranes
4. Multiple opiate receptor sites on primary afferent fibres
5. Indirect evidence for presynaptic location of opiate receptors on chemosensitive primary sensory neurones
6. Spectrum of the μ-, δ- and κ-binding sites in homogenates of rat brain
7. Selective reduction by noradrenaline and 5-hydroxytryptamine of nociceptive response of cat dorsal horn neurones
8. Segmental and descending influences on intraspinal thresholds of single C-fibres
9. Opiate analgesics inhibit substance P release from rat trigeminal nucleus
10. Contribution of sensory afferents and sympathetic efferents to joint injury in experimental arthritis
11. Opposite effects of δ and μ opioid receptor agonists on the in vitro release of substance P-like material from the rat spinal cord
12. Enkephalin inhibits release of substance P from sensory neurons in culture and decreases action potential duration
13. Dose-dependent effects of capsaicin on primary sensory neurons in the neonatal rat
14. Immunocytochemical evidence for a serotoninergic innervation of dorsal column postsynaptic neurons in cat and monkey: light- and electron-microscopic observations
15. Analgesia induced by electrical stimulation of the inferior centralis nucleus of the raphe in the cat
16. Morphine and norepinephrine but not 5-hydroxytryptamine and γ-aminobutyric acid inhibit the potassium-stimulated release of substance P from rat spinal cord slices
17. Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors
18. Nucleus raphe magnus modulation of response of rat dorsal horn neurons to unmyelinated fiber inputs: partial involvement of serotonergic pathways
19. Increase in serotonin metabolism within the dorsal horn of the spinal cord during nucleus raphe magnus stimulation, as revealed by in vivo electrochemical detection
20. Neurochemistry and neural circuitry in the dorsal horn
21. High-affinity serotonin binding sites: autoradiographic evidence for their location on retinal afferents in the rat superior colliculus
22. 1 receptor subtypes in the brain of control and 5,7-dihydroxytryptamine-treated rats
23. Spinal opiate analgesia: characteristics and principles of action
24. Spinal serotonin (5-HT) receptor subtypes and nociception