-
1
-
-
84942223142
-
Pharmacokinetics and metabolism of diuretics. In:
-
Bridges, J.W. and Chasseaud, L.F., eds, Progress in Drug Metabolism, Volume Chichester: John Wiley and Sons
-
Ings, R.M.J., and Stevens, L.A. Pharmacokinetics and metabolism of diuretics. In: Bridges, J.W. and Chasseaud, L.F., eds, Progress in Drug Metabolism, Volume 7. Chichester: John Wiley and Sons, 1983; 129–45.
-
, vol.7
, pp. 129-145
-
-
Ings, R.M.J.1
Stevens, L.A.2
-
2
-
-
0017031277
-
Species differences in the metabolism and disposition of spironolactone
-
Karim, A., Kook, C., Zitzewitz, DJ., Zagarella, J., Doherty, M. and Campion, J. Species differences in the metabolism and disposition of spironolactone. Drug Metab. Dispos. 1976;: 547–555.
-
(1976)
Drug Metab. Dispos
, pp. 547-555
-
-
Karim, A.1
Kook, C.2
Zitzewitz, D.J.3
Zagarella, J.4
Doherty, M.5
Campion, J.6
-
3
-
-
0012020788
-
A fluorimetric method for the determination of a major spironolactone (Aldactone) metabolite in human plasma
-
Gochman, N. and Gantt, C.L. A fluorimetric method for the determination of a major spironolactone (Aldactone) metabolite in human plasma. J. Pharmacol. Exp. Ther. 1962; 135: 312–316.
-
(1962)
J. Pharmacol. Exp. Ther
, vol.135
, pp. 312-316
-
-
Gochman, N.1
Gantt, C.L.2
-
4
-
-
8544251396
-
Pharmacokinetics of Aldactone in humans. In:
-
Brendel, W., Coraboeuf, E., Ebling, FJ.G. et al, eds, Amsterdam: Excerpta Medica
-
Sadee, W., Dagcioglu, M. and Schroder, R. Pharmacokinetics of Aldactone in humans. In: Brendel, W., Coraboeuf, E., Ebling, FJ.G. et al, eds, Extrarenal activity of Aldosterone and its antagonists. Amsterdam: Excerpta Medica 1972; 40–42.
-
(1972)
Extrarenal activity of Aldosterone and its antagonists
, pp. 40-42
-
-
Sadee, W.1
Dagcioglu, M.2
Schroder, R.3
-
5
-
-
0017653496
-
Spironolactone and canrenoate-K: Relative potency at steady-state
-
Ramsay, L., Asbury, M., Shelton, J. and Harrison I. Spironolactone and canrenoate-K: Relative potency at steady-state. Clin. Pharmacol. Ther. 1977; 21: 602–609.
-
(1977)
Clin. Pharmacol. Ther
, vol.21
, pp. 602-609
-
-
Ramsay, L.1
Asbury, M.2
Shelton, J.3
Harrison, I.4
-
6
-
-
0008280877
-
Zum Stoffwechsel von 3-(3-Oxo-7α acetyl - thio - 7β- hydroxy 4 -androsten -17α-yl)-propionsaure-γ-lacton
-
Gerhards, E. and Engelhardt, R. Zum Stoffwechsel von 3-(3-Oxo-7α acetyl - thio - 7β- hydroxy 4 -androsten -17α-yl)-propionsaure-γ-lacton. Arzneim. Forsch. 1963; 13: 972–977.
-
(1963)
Arzneim. Forsch
, vol.13
, pp. 972-977
-
-
Gerhards, E.1
Engelhardt, R.2
-
7
-
-
76549146555
-
Dünnschicht-chromatographische Untersuchungen des 3-(3-Oxo-7α-acetylthio-l 7β-hydroxy-4-androsten-17α-yl)-propionsäure-γ-lactons und seiner Meta-boliten beim Menschen
-
Zicha, L., Weist, F., Scheiffarth, F., and Schmid, E. Dünnschicht-chromatographische Untersuchungen des 3-(3-Oxo-7α-acetylthio-l 7β-hydroxy-4-androsten-17α-yl)-propionsäure-γ-lactons und seiner Meta-boliten beim Menschen. Arzneim. Forsch. 1964; 14: 699–705.
-
(1964)
Arzneim. Forsch
, vol.14
, pp. 699-705
-
-
Zicha, L.1
Weist, F.2
Scheiffarth, F.3
Schmid, E.4
-
8
-
-
0014081380
-
Aldadien und andere Metaboliten im Blut und Ham nach rectaler Applikation von Spironolacton und intravenoser Injektion von Aldadien-Kalium
-
Wayner, H., Weist, F. and Zicha, L. Aldadien und andere Metaboliten im Blut und Ham nach rectaler Applikation von Spironolacton und intravenoser Injektion von Aldadien-Kalium. Arzneim Forsch. 1967; 17: 415–419.
-
(1967)
Arzneim Forsch
, vol.17
, pp. 415-419
-
-
Wayner, H.1
Weist, F.2
Zicha, L.3
-
9
-
-
0015370920
-
Isolation and identification of novel sulfur-containing metabolites of spironolactone (Aldactone)
-
Karim, A. and Brown, E.A. Isolation and identification of novel sulfur-containing metabolites of spironolactone (Aldactone). Steroids 1972; 20:41-62.
-
(1972)
Steroids
, vol.20
, pp. 41-62
-
-
Karim, A.1
Brown, E.A.2
-
10
-
-
0016724604
-
Spironolactone metabolism in man studied by gas chromatography-mass spectrometry
-
Karim, A., Hribar, J., Aksamit, W., Doherty, M., and Chinn, LJ. Spironolactone metabolism in man studied by gas chromatography-mass spectrometry. Drug Metab. Dispos. 1975; 3: 467–478.
-
(1975)
Drug Metab. Dispos
, vol.3
, pp. 467-478
-
-
Karim, A.1
Hribar, J.2
Aksamit, W.3
Doherty, M.4
Chinn, L.J.5
-
11
-
-
0017262778
-
Spironolactone. I. Disposition and metabolism
-
Karim, A., Zagarella, J., Hribary, J. and Dooley, M. Spironolactone. I. Disposition and metabolism. Gin. Pharmacol. Ther. 1975; 19: 158–169.
-
(1975)
Gin. Pharmacol. Ther
, vol.19
, pp. 158-169
-
-
Karim, A.1
Zagarella, J.2
Hribary, J.3
Dooley, M.4
-
12
-
-
0017030714
-
Isolation and identification of a sulfur-containing metabolite of spironolactone from human urine
-
Abshagen, U. and Rennekamp, H. Isolation and identification of a sulfur-containing metabolite of spironolactone from human urine. Steroids 1976; 28: 467–480.
-
(1976)
Steroids
, vol.28
, pp. 467-480
-
-
Abshagen, U.1
Rennekamp, H.2
-
14
-
-
0017726321
-
Spironolactone: diversity in metabolic pathways
-
Karim, H., Hribar, J., Doherty, M., Aksamit, W., Chappelow, D., Brown, E., Markos, C., Chinn, LJ., Liang, D. and Zagarella, J. Spironolactone: diversity in metabolic pathways. Xenobiotica 1977; 7: 585–600.
-
(1977)
Xenobiotica
, vol.7
, pp. 585-600
-
-
Karim, H.1
Hribar, J.2
Doherty, M.3
Aksamit, W.4
Chappelow, D.5
Brown, E.6
Markos, C.7
Chinn, L.J.8
Liang, D.9
Zagarella, J.10
-
15
-
-
0016221360
-
Conversion of spironolactone to canrenone and disposition kinetics of spironolactone and canrenoate-potassium in rats
-
Sadee, W., Abshagen, U., Finn, C. and Rietbrock, N. Conversion of spironolactone to canrenone and disposition kinetics of spironolactone and canrenoate-potassium in rats. Naunyn-Schmied. Arch. Pharmacol. 1974; 283: 303–318.
-
(1974)
Naunyn-Schmied. Arch. Pharmacol
, vol.283
, pp. 303-318
-
-
Sadee, W.1
Abshagen, U.2
Finn, C.3
Rietbrock, N.4
-
16
-
-
0015053937
-
Pharmacokinetic and metabolic fate of potassium canrenoate (SC-14266) in man
-
Karim, A., Ranney, R.E. and Maibach, HJ. Pharmacokinetic and metabolic fate of potassium canrenoate (SC-14266) in man. J. Pharm. Sci. 1971; 60: 708–715.
-
J. Pharm. Sci.
, vol.60
, pp. 708-715
-
-
Karim, A.1
Ranney, R.E.2
Maibach, H.J.3
-
17
-
-
0015170248
-
Prediction of stability in pharmaceutical preparations XVI: Kinetics of hydrolysis of canrenone and lactonization of canrenoic acid
-
Garrett, E.R. and Won, C.M. Prediction of stability in pharmaceutical preparations XVI: Kinetics of hydrolysis of canrenone and lactonization of canrenoic acid. J. Pharm. Sci. 1971; 60: 1801–1809.
-
J. Pharm. Sci.
, vol.60
, pp. 1801-1809
-
-
Garrett, E.R.1
Won, C.M.2
-
18
-
-
0015713162
-
Pharmacokinetics of spironolactone, canrenone and canrenoate-K in humans
-
Sadee, W., Dagcioglu, M. and Schroder, R. Pharmacokinetics of spironolactone, canrenone and canrenoate-K in humans. J. Pharmacol. Exp. Ther. 1973; 185: 686–695.
-
(1973)
J. Pharmacol. Exp. Ther
, vol.185
, pp. 686-695
-
-
Sadee, W.1
Dagcioglu, M.2
Schroder, R.3
-
19
-
-
0016615752
-
Aldosterone plasma radioimmunoassay interference by a spirolactone metabolite
-
Sadee, W., Finn, A.M., Schmiedek, P. and Baethmann, A. Aldosterone plasma radioimmunoassay interference by a spirolactone metabolite. Steroids 1975; 25: 301–311.
-
(1975)
Steroids
, vol.25
, pp. 301-311
-
-
Sadee, W.1
Finn, A.M.2
Schmiedek, P.3
Baethmann, A.4
-
20
-
-
0020887083
-
Metabolism of spirolactones by the rat testis in vitro
-
Weissenborn, U. and Erbler, H.C. Metabolism of spirolactones by the rat testis in vitro. Steroids 1983;42: 365–388.
-
(1983)
Steroids
, vol.42
, pp. 365-388
-
-
Weissenborn, U.1
Erbler, H.C.2
-
21
-
-
84942223310
-
Pharmacokinetics and metabolism of canrenone and canrenoic acid after an oral dose of potassium canrenoate or spironolactone in the rat
-
Koch, R.L., Hauswald, C.L. and Oppermann, J.A. Pharmacokinetics and metabolism of canrenone and canrenoic acid after an oral dose of potassium canrenoate or spironolactone in the rat. Pharmacologist 1984; 26: 167.
-
(1984)
Pharmacologist
, vol.26
, pp. 167
-
-
Koch, R.L.1
Hauswald, C.L.2
Oppermann, J.A.3
-
22
-
-
0018696149
-
Identification of some human urinary metabolites of orally administered potassium canrcnoate by stable-isotope labelling techniques
-
Vose, C.W., Boreham, D.R., Ford, G.C., Haskins, NJ. and Palmer, R.F. Identification of some human urinary metabolites of orally administered potassium canrcnoate by stable-isotope labelling techniques. Drug Metab. Dispos. 1979; 7: 226–32.
-
(1979)
Drug Metab. Dispos
, vol.7
, pp. 226-232
-
-
Vose, C.W.1
Boreham, D.R.2
Ford, G.C.3
Haskins, N.J.4
Palmer, R.F.5
-
23
-
-
0019833827
-
Conversion of spironolactone to an active metabolite in target tissues: Formation of 7a-thiospironolactone by microsomal preparations from guinea pig liver, adrenals, kidneys, and testes
-
Sherry, J.H., O'Donnell, J.P. and Colby, H.D. Conversion of spironolactone to an active metabolite in target tissues: Formation of 7a-thiospironolactone by microsomal preparations from guinea pig liver, adrenals, kidneys, and testes. Life Sci. 1981; 29: 2727–2736.
-
(1981)
Life Sci
, vol.29
, pp. 2727-2736
-
-
Sherry, J.H.1
O'Donnell, J.P.2
Colby, H.D.3
-
24
-
-
0022516551
-
Metabolism of spironolactone by adrenocortical and hepatic microsomes: Relationship to cytochrome p 450 destruction
-
Sherry, J.H., O'Donnell, J.P., Flowers, L., Lacagnin, L.B. and Colby, H.D. Metabolism of spironolactone by adrenocortical and hepatic microsomes: Relationship to cytochrome P450 destruction. J.Pharmacol. Exp. Ther. 1986; 236: 675-680.
-
(1986)
J. Pharmacol. Exp. Ther
, vol.236
, pp. 675-680
-
-
Sherry, J.H.1
O'Donnell, J.P.2
Flowers, L.3
Lacagnin, L.B.4
Colby, H.D.5
-
25
-
-
0018345059
-
Effect of spironolactone and its main metabolite canrenone on the renin-angiotensin-aldosterone-system during long-term treatment in rats
-
Erbler, H.C. Effect of spironolactone and its main metabolite canrenone on the renin-angiotensin-aldosterone-system during long-term treatment in rats. Acta Endocrinol. 1979; 90: 147–156.
-
(1979)
Acta Endocrinol
, vol.90
, pp. 147-156
-
-
Erbler, H.C.1
-
26
-
-
0021743179
-
Human erythrocyte membrane thiol methyltransferase. S-Methylation of captopril, N-acetyl-cysteine, and 7α-thio-spirolactone
-
Keith, R.A., Jardine, I., Kerremans, A. and Weinshilboum, R.M. Human erythrocyte membrane thiol methyltransferase. S-Methylation of captopril, N-acetyl-cysteine, and 7α-thio-spirolactone. Drug Metab. Dispos. 1984; 12: 717–724.
-
(1984)
Drug Metab. Dispos
, vol.12
, pp. 717-724
-
-
Keith, R.A.1
Jardine, I.2
Kerremans, A.3
Weinshilboum, R.M.4
-
27
-
-
0015368856
-
Fluorimetric microassay for spironolactone and its metabolites in biological fluids
-
Sadee, W., Dagcioglu, M. and Riegelman, S. Fluorimetric microassay for spironolactone and its metabolites in biological fluids. J. Pharm. Sci. 1972; 61: 1126–1128.
-
(1972)
J. Pharm. Sci
, vol.61
, pp. 1126-1128
-
-
Sadee, W.1
Dagcioglu, M.2
Riegelman, S.3
-
28
-
-
0017713793
-
Simultaneous automated determination of spironolactone metabolites in serum
-
Neubert, P. and Koch, K. Simultaneous automated determination of spironolactone metabolites in serum. J. Pharm. Sci. 1977; 66: 1131–1134.
-
(1977)
J. Pharm. Sci
, vol.66
, pp. 1131-1134
-
-
Neubert, P.1
Koch, K.2
-
29
-
-
0018418573
-
Re-evaluation of the anti-mineralocorticoid effect of the spironolactone metabolite, canrenone, from plasma concentrations determined by a new high-pressure liquid-chromatographic method
-
Dahlof, C.G., Lundborg, P., Persson, B.A. and Regardh, C.G. Re-evaluation of the anti-mineralocorticoid effect of the spironolactone metabolite, canrenone, from plasma concentrations determined by a new high-pressure liquid-chromatographic method. Drug Metab. Dispos. 1979; 7: 103–107.
-
(1979)
Drug Metab. Dispos
, vol.7
, pp. 103-107
-
-
Dahlof, C.G.1
Lundborg, P.2
Persson, B.A.3
Regardh, C.G.4
-
30
-
-
0018761808
-
High-performance liquid chromatographic determination of canrenone, a major metabolite of spironolactone, in body fluids
-
Neurath, G.B. and Ambrosius, D. High-performance liquid chromatographic determination of canrenone, a major metabolite of spironolactone, in body fluids. J. Chromatogr. 1979; 163; 230-255.
-
(1979)
J. Chromatogr
, vol.163
, pp. 230-255
-
-
Neurath, G.B.1
Ambrosius, D.2
-
31
-
-
0018692757
-
Kinetics of canrenone after single and multiple doses of spironolactone
-
Abshagen, U., Besenfelder, E., Endele, R., Koch, K. and Neubert, B. Kinetics of canrenone after single and multiple doses of spironolactone. Eur. J. Clin. Pharmacol. 1979; 16: 255–262.
-
(1979)
Eur. J. Clin. Pharmacol
, vol.16
, pp. 255-262
-
-
Abshagen, U.1
Besenfelder, E.2
Endele, R.3
Koch, K.4
Neubert, B.5
-
32
-
-
84983864350
-
High performance liquid chromatographic method for determination of canrenone in serum
-
Besenfelder, E. and Endele, R. High performance liquid chromatographic method for determination of canrenone in serum. J. High Resolut. Chromatogr. Commun. 1981; 4: 419-421.
-
(1981)
J. High Resolut. Chromatogr. Commun
, vol.4
, pp. 419-421
-
-
Besenfelder, E.1
Endele, R.2
-
33
-
-
0019483026
-
Zur Spezifitat der Bestimmung von Canrenon in biologischen Flüssigkeiten
-
Stuber, W., Mutschler, E. and Steinbach, D. Zur Spezifitat der Bestimmung von Canrenon in biologischen Flüssigkeiten. Arch. Pharm. 1981; 314: 148–156.
-
(1981)
Arch. Pharm
, vol.314
, pp. 148-156
-
-
Stuber, W.1
Mutschler, E.2
Steinbach, D.3
-
34
-
-
0020680946
-
Pharmacokinetics of spironolactone after a single dose: Evaluation of the true canrenone serum concentrations during 24 hours
-
Merkus, F.W.H.M., Overdiek, J.W.P.M., Cilissen, J. and Zuidema, J. Pharmacokinetics of spironolactone after a single dose: Evaluation of the true canrenone serum concentrations during 24 hours. Clin. Exp. Hypertens. 1983; A5: 239–248.
-
(1983)
Clin. Exp. Hypertens
, vol.A5
, pp. 239-248
-
-
Merkus, F.W.H.M.1
Overdiek, J.W.P.M.2
Cilissen, J.3
Zuidema, J.4
-
35
-
-
0021046819
-
Pharmacokinetics of canrenone after oral administration of spironolactone and intravenous injection of canrenoate-Kin healthy man
-
Krause, W., Karras, J. and Seifert, W. Pharmacokinetics of canrenone after oral administration of spironolactone and intravenous injection of canrenoate-Kin healthy man. Eur. J. Clin. Pharmacol. 1983; 25: 449–453.
-
(1983)
Eur. J. Clin. Pharmacol
, vol.25
, pp. 449-453
-
-
Krause, W.1
Karras, J.2
Seifert, W.3
-
36
-
-
84942225037
-
The importance of canrenone in the metabolism of spironolactone
-
Overdiek, J.W.P.M., Cilissen, J., Hermens, W.AJJ. and Merkus, F.W.H.M. The importance of canrenone in the metabolism of spironolactone. Pharm. Weekbl. Sci. Ed. 1984; 6: 270.
-
(1984)
Pharm. Weekbl. Sci. Ed
, vol.6
, pp. 270
-
-
Overdiek, J.W.P.M.1
Cilissen, J.2
Hermens, W.A.J.J.3
Merkus, F.W.H.M.4
-
37
-
-
0021675720
-
Pharmacokinetics of canrenone and metabolites after base hydrolysis following single and multiple dose oral administration of spironolactone
-
Ho, P.C., Bourne, D.W.A., Triggs, E.J. and Heazlewood, V. Pharmacokinetics of canrenone and metabolites after base hydrolysis following single and multiple dose oral administration of spironolactone. Eur. J. Clin. Pharmacol. 1984; 27: 441–446.
-
(1984)
Eur. J. Clin. Pharmacol
, vol.27
, pp. 441-446
-
-
Ho, P.C.1
Bourne, D.W.A.2
Triggs, E.J.3
Heazlewood, V.4
-
38
-
-
0021957690
-
Pharmacokinetics of spironolactone and potassium canrenoate in humans
-
Kojima, K., Yamamoto, K., Fujioka, H. and Kaneko, H. Pharmacokinetics of spironolactone and potassium canrenoate in humans. J. Pharmacobio-Dyn. 1985; 8: 161–166.
-
(1985)
J. Pharmacobio-Dyn
, vol.8
, pp. 161-166
-
-
Kojima, K.1
Yamamoto, K.2
Fujioka, H.3
Kaneko, H.4
-
39
-
-
0015208788
-
Gas chromatographic determination of levels of aldadiene in human plasma and urine following therapeutic doses of spironolactone
-
Chamberlain, J. Gas chromatographic determination of levels of aldadiene in human plasma and urine following therapeutic doses of spironolactone. J. Chromatogr. 1971; 55: 249–253.
-
(1971)
J. Chromatogr
, vol.55
, pp. 249-253
-
-
Chamberlain, J.1
-
40
-
-
0017298112
-
Simple gas chromatographic method with flame ionization detection for the determination of aldadiene in human urine
-
Feher, T., Bodrogi, L. and Varadi, A. Simple gas chromatographic method with flame ionization detection for the determination of aldadiene in human urine. J. Chromatogr. 1976; 123: 460–462.
-
(1976)
J. Chromatogr
, vol.123
, pp. 460-462
-
-
Feher, T.1
Bodrogi, L.2
Varadi, A.3
-
41
-
-
0021815793
-
Determination of the serum concentration of spironolactone and its metabolites by high-performance liquid chromatography
-
Overdiek, J.W.P.M., Hermens, W.A.J.J. and Merkus, F.W.H.M. Determination of the serum concentration of spironolactone and its metabolites by high-performance liquid chromatography. J. Chromatogr. 1985; 341: 279–285.
-
(1985)
J. Chromatogr
, vol.341
, pp. 279-285
-
-
Overdiek, J.W.P.M.1
Hermens, W.A.J.J.2
Merkus, F.W.H.M.3
-
42
-
-
0019406179
-
Bioverfügbarkeitsuntersuchung zweier Spironolacton-Praparate
-
Von Vergin, H., Nuss, U., Schwarzländer, F., Strobel, K., Weigand, W. and Hitzenberger, G. Bioverfügbarkeitsuntersuchung zweier Spironolacton-Praparate. Arzneim. Forsch. 1981; 31: 1498–1503.
-
(1981)
Arzneim. Forsch
, vol.31
, pp. 1498-1503
-
-
Von Vergin, H.1
Nuss, U.2
SchwarzläNder, F.3
Strobel, K.4
Weigand, W.5
Hitzenberger, G.6
-
44
-
-
0017167531
-
Pharmakokinetik von Aldosteron-Antagonisten
-
Sponer, G., Kaufmann, B. and Kuhr, M. Pharmakokinetik von Aldosteron-Antagonisten. Krankenhausarzt 1976; 49: 569–575.
-
(1976)
Krankenhausarzt
, vol.49
, pp. 569-575
-
-
Sponer, G.1
Kaufmann, B.2
Kuhr, M.3
-
45
-
-
0017113909
-
Spironolactone and potassium canrenoate in normal man
-
Ramsay, L., Shelton, J., Harrison, I., Tidd,M. and Asbury, M. Spironolactone and potassium canrenoate in normal man. Clin. Pharmacol. Ther. 1976; 20: 167–177.
-
(1976)
Clin. Pharmacol. Ther
, vol.20
, pp. 167-177
-
-
Ramsay, L.1
Shelton, J.2
Harrison, I.3
Tidd, M.4
Asbury, M.5
-
46
-
-
0017330993
-
Elimination of canrenone in congestive heart failure and chronic liver disease
-
Jackson, L., Branch, R., Levine, D. and Ramsay, L. Elimination of canrenone in congestive heart failure and chronic liver disease. Eur. J. Clin. Pharmacol. 1977; 11: 177–179.
-
(1977)
Eur. J. Clin. Pharmacol
, vol.11
, pp. 177-179
-
-
Jackson, L.1
Branch, R.2
Levine, D.3
Ramsay, L.4
-
47
-
-
0018164753
-
Spironolactone: disposition, metabolism, pharmacodynamics, and bioavailability
-
Karim, A. Spironolactone: disposition, metabolism, pharmacodynamics, and bioavailability. Drug Metab. Rev. 1978; 8: 151–188.
-
(1978)
Drug Metab. Rev
, vol.8
, pp. 151-188
-
-
Karim, A.1
-
48
-
-
0022642772
-
Untersuchungen zur Pharmakokinetik und Bioverfügbarkeit von Bendroflumethiazid in Kombination mit Spironolacton
-
Von Vergin, H., Nuss, U. and Strobel, K. Untersuchungen zur Pharmakokinetik und Bioverfügbarkeit von Bendroflumethiazid in Kombination mit Spironolacton. Arzneim. Forsch. 1986; 36: 490–495.
-
(1986)
Arzneim. Forsch
, vol.36
, pp. 490-495
-
-
Von Vergin, H.1
Nuss, U.2
Strobel, K.3
-
49
-
-
0017624810
-
Effect of enterohepatic circulation on the pharmacokinetics of spironolactone in man
-
Abshagen, U., Von Grodzicki, U., Hirschberger, U. and Rennekamp, H. Effect of enterohepatic circulation on the pharmacokinetics of spironolactone in man. Naunyn-Schmied. Arch. Pharmacol. 1977; 300: 281–287.
-
(1977)
Naunyn-Schmied. Arch. Pharmacol
, vol.300
, pp. 281-287
-
-
Abshagen, U.1
Von Grodzicki, U.2
Hirschberger, U.3
Rennekamp, H.4
-
50
-
-
0016159584
-
Multiple dose kinetics of spironolactone and canrenoate-potassium in cardiac and hepatic failure
-
Sadee, W., Schroder, R., Von Leitner, E. and Dagcioglu, M. Multiple dose kinetics of spironolactone and canrenoate-potassium in cardiac and hepatic failure. Eur. J. Clin. Pharmacol. 1974; 7: 195–200.
-
(1974)
Eur. J. Clin. Pharmacol
, vol.7
, pp. 195-200
-
-
Sadee, W.1
Schroder, R.2
Von Leitner, E.3
Dagcioglu, M.4
-
51
-
-
0017363407
-
Disposition kinetics of spironolactone in hepatic failure after single doses and prolonged treatment
-
Abshagen, U., Rennekamp, H. and Luszpinski, G. Disposition kinetics of spironolactone in hepatic failure after single doses and prolonged treatment. Eur. J. Clin. Pharmacol. 1977; 11: 169–176.
-
(1977)
Eur. J. Clin. Pharmacol
, vol.11
, pp. 169-176
-
-
Abshagen, U.1
Rennekamp, H.2
Luszpinski, G.3
-
52
-
-
0017725077
-
Spironolactone metabolism in normal subjects and in patients with liver cirrhosis
-
Varadi, A., Feher, T., Bodrogi, L. and Koref, O. Spironolactone metabolism in normal subjects and in patients with liver cirrhosis. Arzneim. Forsch. 1977; 27: 1617–1620.
-
(1977)
Arzneim. Forsch
, vol.27
, pp. 1617-1620
-
-
Varadi, A.1
Feher, T.2
Bodrogi, L.3
Koref, O.4
-
53
-
-
0022622694
-
Spironolactone metabolism and gynaecomastia
-
Overdiek, J.W.P.M. and Merkus, F.W.H.M. Spironolactone metabolism and gynaecomastia. Lancet 1986; 1: 1103.
-
(1986)
Lancet
, vol.1
, pp. 1103
-
-
Overdiek, J.W.P.M.1
Merkus, F.W.H.M.2
-
54
-
-
0019391165
-
Zur Pharmakokinetik von Spironolacton im Alter
-
Abshagen, U., Platt, D. and Horn, HJ. Zur Pharmakokinetik von Spironolacton im Alter. Klin. Wochenschr. 1981; 59: 909–910.
-
(1981)
Klin. Wochenschr
, vol.59
, pp. 909-910
-
-
Abshagen, U.1
Platt, D.2
Horn, H.J.3
-
55
-
-
0021169571
-
The influence of age and multimorbidity on the pharmacokinetics and metabolism of spironolactone
-
Platt, D., Abshagen, U., Mühlberg, W., Horn, HJ., Schmitt-Ruth, R. and Vollmar, J. The influence of age and multimorbidity on the pharmacokinetics and metabolism of spironolactone. Arch. Gerontol Geriatr. 1984; 3: 147–159.
-
(1984)
Arch. Gerontol Geriatr
, vol.3
, pp. 147-159
-
-
Platt, D.1
Abshagen, U.2
MüHlberg, W.3
Horn, H.J.4
Schmitt-Ruth, R.5
Vollmar, J.6
-
56
-
-
0021738021
-
Comparison of plasma levels of canrenone and metabolites after base hydrolysis in young and elderly subjects following single and multiple doses of spironolactone
-
Ho, P.C., Bourne, D.W.A., Triggs, E J. and Smithurst, B.A. Comparison of plasma levels of canrenone and metabolites after base hydrolysis in young and elderly subjects following single and multiple doses of spironolactone. Eur. J. Clin. Pharmacol. 1984; 27: 435–439.
-
(1984)
Eur. J. Clin. Pharmacol
, vol.27
, pp. 435-439
-
-
Ho, P.C.1
Bourne, D.W.A.2
Triggs, EJ.3
Smithurst, B.A.4
-
57
-
-
0004926439
-
Effect of a detergent on gastrointestinal absorption of a steroid
-
Gantt, C.L., Gochman, N. and Dyniewicz, J.M. Effect of a detergent on gastrointestinal absorption of a steroid. Lancet 1986; 1: 486–487.
-
(1986)
Lancet
, vol.1
, pp. 486-487
-
-
Gantt, C.L.1
Gochman, N.2
Dyniewicz, J.M.3
-
58
-
-
8544246542
-
Gastrointestinal absorption of spironolactone
-
Gantt, C.L., Gochman, N. and Dyniewicz, J.M. Gastrointestinal absorption of spironolactone. Lancet 1962; 1: 1130–1131.
-
(1962)
Lancet
, vol.1
, pp. 1130-1131
-
-
Gantt, C.L.1
Gochman, N.2
Dyniewicz, J.M.3
-
59
-
-
84977298268
-
The estimation of the activity of aldosterone antagonist in man: spironolactone (Aldactone) activity
-
Noel, P.R. and Leahy, J.S. The estimation of the activity of aldosterone antagonist in man: spironolactone (Aldactone) activity. Clin. Sci. 1962; 23: 477–483.
-
(1962)
Clin. Sci
, vol.23
, pp. 477-483
-
-
Noel, P.R.1
Leahy, J.S.2
-
60
-
-
78651144896
-
Oral absorption with various preparations of spironolactone in dogs
-
Kagawa, C.M., Bouska, DJ. and Anderson, M.L. Oral absorption with various preparations of spironolactone in dogs. J. Pharm. Sci. 1964; 53: 450–451.
-
(1964)
J. Pharm. Sci
, vol.53
, pp. 450-451
-
-
Kagawa, C.M.1
Bouska, D.J.2
Anderson, M.L.3
-
61
-
-
73049175715
-
Einfluss von Teilchengrosse und Losungsvermittlern auf die Resorption von Spironolacton aus dem Magen-Darmtrakt
-
Bauer, G., Rieckmann, P. and Schaumann, W. Einfluss von Teilchengrosse und Losungsvermittlern auf die Resorption von Spironolacton aus dem Magen-Darmtrakt. Arzneim. Forsch. 1962; 12: 487–489.
-
(1962)
Arzneim. Forsch
, vol.12
, pp. 487-489
-
-
Bauer, G.1
Rieckmann, P.2
Schaumann, W.3
-
62
-
-
0019591216
-
Etude comparative des disponibilites de deux formes de spironolactone
-
D'Athis, P., Richard, M.O., De Lauture, D., Rey, E., Bouvier d’Yvoire, M., Clement, E. and Olive, G. Etude comparative des disponibilites de deux formes de spironolactone. Therapie 1981; 36: 443–449.
-
(1981)
Therapie
, vol.36
, pp. 443-449
-
-
D'Athis, P.1
Richard, M.O.2
De Lauture, D.3
Rey, E.4
Bouvier D'Yvoire, M.5
Clement, E.6
Olive, G.7
-
63
-
-
84942225140
-
Des aspects de la biodisponibilite physiologique de la spironolactone et de la canrenone
-
Portal, A., Gaillot, J., Bieder, A., Rodary, C. and Bertharion, J J. Des aspects de la biodisponibilite physiologique de la spironolactone et de la canrenone. Sem. Hôp. 1976; 5: 465–470.
-
(1976)
Sem. Hôp
, vol.5
, pp. 465-470
-
-
Portal, A.1
Gaillot, J.2
Bieder, A.3
Rodary, C.4
Bertharion, JJ.5
-
64
-
-
0019946573
-
Effect of micronization on the bioavailability and Pharmacologic activity of spironolactone
-
Mclnnes, G.T., Asbury, MJ., Ramsay, L.E., Shelton, J.R. and Harrison, I.R. Effect of micronization on the bioavailability and Pharmacologic activity of spironolactone. J. Clin. Pharmacol. 1982; 22: 410–417.
-
(1982)
J. Clin. Pharmacol
, vol.22
, pp. 410-417
-
-
Mclnnes, G.T.1
Asbury, M.J.2
Ramsay, L.E.3
Shelton, J.R.4
Harrison, I.R.5
-
65
-
-
0343828662
-
Availability of spironolactone given by mouth
-
Levy, G. Availability of spironolactone given by mouth. Lancet 1962; 2: 723–724.
-
(1962)
Lancet
, vol.2
, pp. 723-724
-
-
Levy, G.1
-
66
-
-
0017670012
-
Factors influencing comparative bioavailability of spironolactone tablets
-
Clarke, J.M., Ramsay, L.E., Shelton, J.R., Tidd, M.J., Murray, S. and Palmer, R.F. Factors influencing comparative bioavailability of spironolactone tablets. J. Pharm. Sci. 1977; 66: 1429–1432.
-
(1977)
J. Pharm. Sci
, vol.66
, pp. 1429-1432
-
-
Clarke, J.M.1
Ramsay, L.E.2
Shelton, J.R.3
Tidd, M.J.4
Murray, S.5
Palmer, R.F.6
-
67
-
-
0017237934
-
A comparison of the dissolution and bioavailability characteristics of three spironolactone tablet formulations, including preliminary data on two spironolactone metabolites
-
Tidd, K.J., Collins, W.I. and Chamberlain, J. A comparison of the dissolution and bioavailability characteristics of three spironolactone tablet formulations, including preliminary data on two spironolactone metabolites. J. Int. Med. Res. 1976; 4: 86–95.
-
(1976)
J. Int. Med. Res
, vol.4
, pp. 86-95
-
-
Tidd, K.J.1
Collins, W.I.2
Chamberlain, J.3
-
68
-
-
0018125442
-
In vitro and in vivo availability of spironolactone from various oral preparations
-
Raptis, G., Wendt, H., Meister, R. and Fuchs, P. In vitro and in vivo availability of spironolactone from various oral preparations. Drug. Dev. Ind. Pharm. 1978; 4: 389–411.
-
(1978)
Drug. Dev. Ind. Pharm
, vol.4
, pp. 389-411
-
-
Raptis, G.1
Wendt, H.2
Meister, R.3
Fuchs, P.4
-
69
-
-
0017098237
-
In vitro and in vivo availability of spironolactone from oral dosage forms
-
Chao, A.Y., Sanvordeker, D.R., Zagarella, J., Mattes, K., Nicholova, B. and Karim, A. In vitro and in vivo availability of spironolactone from oral dosage forms. J. Pharm. Sci. 1976; 65: 1630–1634.
-
(1976)
J. Pharm. Sci
, vol.65
, pp. 1630-1634
-
-
Chao, A.Y.1
Sanvordeker, D.R.2
Zagarella, J.3
Mattes, K.4
Nicholova, B.5
Karim, A.6
-
70
-
-
0017295858
-
Spironolactone, II. Bioavailability
-
Karim, A., Zagarella, J., Hutsell, T.C., Chao, A.Y. and Baltes, BJ. Spironolactone, II. Bioavailability. Clin. Pharmacol. Ther. 1976; 19: 170–176.
-
(1976)
Clin. Pharmacol. Ther
, vol.19
, pp. 170-176
-
-
Karim, A.1
Zagarella, J.2
Hutsell, T.C.3
Chao, A.Y.4
Baltes, B.J.5
-
71
-
-
0016261652
-
Comparison of spironolactone tablet dosage forms in healthy humans
-
Hofmann, L.M., Dutt, J.E., Deysach, L.G., Loncin, H. and Tao, L. Comparison of spironolactone tablet dosage forms in healthy humans. J. Pharm. Sci. 1974; 63: 1248–1253.
-
(1974)
J. Pharm. Sci
, vol.63
, pp. 1248-1253
-
-
Hofmann, L.M.1
Dutt, J.E.2
Deysach, L.G.3
Loncin, H.4
Tao, L.5
-
72
-
-
0018336730
-
Relative bioverfügbarkeit einer neuen Spironolacton-Zubereitung
-
Von Erking, W., Lücker, P.W., Stocker, K.P. and Wetzelsberger, K. Relative bioverfügbarkeit einer neuen Spironolacton-Zubereitung. Arzneim. Forsch. 1979;29: 1184–1189.
-
(1979)
Arzneim. Forsch
, vol.29
, pp. 1184-1189
-
-
Von Erking, W.1
LüCker, P.W.2
Stocker, K.P.3
Wetzelsberger, K.4
-
73
-
-
0018295790
-
Vergleichende Untersuchung der relativen Bioverfügbarkeit mehrerer Spironolacton-Zubereitungen im Steady-state-Versuch
-
Von Rosenthal, J., Jaeger, H. and Specker, M. Vergleichende Untersuchung der relativen Bioverfügbarkeit mehrerer Spironolacton-Zubereitungen im Steady-state-Versuch. Arzneim. Forsch. 1979; 29: 1428–1432.
-
(1979)
Arzneim. Forsch
, vol.29
, pp. 1428-1432
-
-
Von Rosenthal, J.1
Jaeger, H.2
Specker, M.3
-
75
-
-
0021075404
-
The bioavailability of two new preparations of spironolactone tablets
-
Nijkerk, A.J., Vermeer, J.M., Imanse, M. and De Vos, D. The bioavailability of two new preparations of spironolactone tablets. Pharm. Weekbl. Sci. Ed. 1983; 5: 210–212.
-
(1983)
Pharm. Weekbl. Sci. Ed
, vol.5
, pp. 210-212
-
-
Nijkerk, A.J.1
Vermeer, J.M.2
Imanse, M.3
De Vos, D.4
-
76
-
-
0017656913
-
Enhancement by food of canrenone bioavailability from spironolactone
-
Melander, A., Danielson, K. Schersten, B., Thulin, T. and Wahlin, E. Enhancement by food of canrenone bioavailability from spironolactone. Clin. Pharmacol. Ther. 1977; 22: 100–103.
-
(1977)
Clin. Pharmacol. Ther
, vol.22
, pp. 100-103
-
-
Melander, A.1
Danielson, K.2
Schersten, B.3
Thulin, T.4
Wahlin, E.5
-
77
-
-
0022981724
-
Influence of food on the bioavailability of spironolactone
-
Overdiek, J.W.P.M. and Merkus, F.W.H.M. Influence of food on the bioavailability of spironolactone. Clin. Pharmacol. Ther. 1986; 40: 531–536.
-
(1986)
Clin. Pharmacol. Ther
, vol.40
, pp. 531-536
-
-
Overdiek, J.W.P.M.1
Merkus, F.W.H.M.2
-
79
-
-
0344396919
-
Improvement of solubility and bioavailability of spironolactone by inclusion in β-cyclodextrin
-
Debrueres, B., Bretillon, A. and Duchêne, D. Improvement of solubility and bioavailability of spironolactone by inclusion in β-cyclodextrin. Proc. Int. Symp. Control Rel. Bioact. Mater. 1985; 12: 118–119.
-
(1985)
Proc. Int. Symp. Control Rel. Bioact. Mater
, vol.12
, pp. 118-119
-
-
Debrueres, B.1
Bretillon, A.2
DuchêNe, D.3
-
80
-
-
0020585260
-
Enhancement of oral bioavailability of spironolactone by β- and γ-cyclodextrin complexations
-
Seo, H., Sunuoka, M., Hashimoto, T. Fujinaga, T., Otagiri, M. and Uekama, K. Enhancement of oral bioavailability of spironolactone by β- and γ-cyclodextrin complexations. Chem. Pharm. Bull. 1983; 31: 286–291.
-
(1983)
Chem. Pharm. Bull
, vol.31
, pp. 286-291
-
-
Seo, H.1
Sunuoka, M.2
Hashimoto, T.3
Fujinaga, T.4
Otagiri, M.5
Uekama, K.6
-
81
-
-
0021955115
-
Pharmaceutical applications of methylated cyclodextrins
-
Uekama, K. Pharmaceutical applications of methylated cyclodextrins. Pharm. Int. 1985; 6: 61–65.
-
(1985)
Pharm. Int
, vol.6
, pp. 61-65
-
-
Uekama, K.1
-
82
-
-
0022529765
-
Spironolactone/β-cyclodextrin complex: oral bioavailability in humans
-
Vila Jato, J.L., Blanco, J. and Vilar, A. Spironolactone/β-cyclodextrin complex: oral bioavailability in humans. Acta Pharm. Technol. 1986; 32: 82–85.
-
(1986)
Acta Pharm. Technol
, vol.32
, pp. 82-85
-
-
Vila Jato, J.L.1
Blanco, J.2
Vilar, A.3
-
83
-
-
0017229891
-
Binding of drugs to serum albumin
-
Koch-Weser, J. and Sellers, E.M. Binding of drugs to serum albumin. New Engl. J. Med. 1976; 294; 311–316.
-
(1976)
New Engl. J. Med
, vol.294
, pp. 311-316
-
-
Koch-Weser, J.1
Sellers, E.M.2
-
84
-
-
0018840931
-
Distribution coefficients and in vitro human serum protein binding of spironolactone and its 7α-carboxy-methyl analog
-
Ng, A.S., Kluza, R.B. and Newton, D.W. Distribution coefficients and in vitro human serum protein binding of spironolactone and its 7α-carboxy-methyl analog. J. Pharm. Sci. 1980; 69: 30–32.
-
(1980)
J. Pharm. Sci
, vol.69
, pp. 30-32
-
-
Ng, A.S.1
Kluza, R.B.2
Newton, D.W.3
-
85
-
-
0017253360
-
Antagonism of fluorocortisone by spironolactone and canrenone
-
Huston, G.J. and Turner, P. Antagonism of fluorocortisone by spironolactone and canrenone. Br. J. Clin. Pharmacol. 1976; 3: 201–204.
-
(1976)
Br. J. Clin. Pharmacol
, vol.3
, pp. 201-204
-
-
Huston, G.J.1
Turner, P.2
-
86
-
-
0020519687
-
Is canrenone the major metabolite of spironolactone?
-
Merkus, F.W.H.M. Is canrenone the major metabolite of spironolactone? Gin. Pharm. 1983; 2: 209–210.
-
(1983)
Gin. Pharm
, vol.2
, pp. 209-210
-
-
Merkus, F.W.H.M.1
-
87
-
-
0017081089
-
Canrenone — the principal active metabolite of spironolactone?
-
Ramsay, L.E., Shelton, J.R., Wilkinson, D. and Tidd, M.J. Canrenone — the principal active metabolite of spironolactone? Br. J. Gin. Pharmacol. 1976; 3: 607–612.
-
(1976)
Br. J. Gin. Pharmacol
, vol.3
, pp. 607-612
-
-
Ramsay, L.E.1
Shelton, J.R.2
Wilkinson, D.3
Tidd, M.J.4
-
88
-
-
3542999971
-
Acute effects of aldosterone antagonists in volunteers. In:
-
Addison, G.M., Wirenfeldt Asumussen, N., Corvol, P., et al, eds, Amsterdam-Oxford: Excerpta Medica
-
Casals-Stenzel, J., Schmalbach, J. and Losert, W. Acute effects of aldosterone antagonists in volunteers. In: Addison, G.M., Wirenfeldt Asumussen, N., Corvol, P., et al, eds, Aldosterone antagonists in clinical medicine. Amsterdam-Oxford: Excerpta Medica, 1978; 207–216.
-
(1978)
Aldosterone antagonists in clinical medicine
, pp. 207-216
-
-
Casals-Stenzel, J.1
Schmalbach, J.2
Losert, W.3
-
89
-
-
0018869399
-
Activity of sulfur-containing intermediate metabolites of spironolactone
-
Mclnnes, G.T., Asbury, M.J., Shelton, J.R., Harrison, I.R., Ramsay, L.E., Venning, G.R. and Clarke, J.M. Activity of sulfur-containing intermediate metabolites of spironolactone. Clin. Pharmacol. Ther. 1980; 27: 363–369.
-
(1980)
Clin. Pharmacol. Ther
, vol.27
, pp. 363-369
-
-
Mclnnes, G.T.1
Asbury, M.J.2
Shelton, J.R.3
Harrison, I.R.4
Ramsay, L.E.5
Venning, G.R.6
Clarke, J.M.7
-
90
-
-
0011750872
-
Clinical Pharmacology and therapeutic use of aldosterone antagonists. In:
-
Agarwal, M.D., ed, Hormone antagonists. Berlin-New York: Walter de Gruyter and Co.
-
Ramsay, L.E. Clinical Pharmacology and therapeutic use of aldosterone antagonists. In: Agarwal, M.D., ed, Hormone antagonists. Berlin-New York: Walter de Gruyter and Co., 1982; 335–363.
-
-
-
Ramsay, L.E.1
-
91
-
-
84912289784
-
Aldosterone antagonists In laboratory animals. In:
-
Wesson, L.G. and Fanelli, G.M., eds, Baltimore: University Press Park
-
Hofmann, L.M. Aldosterone antagonists in laboratory animals. In: Wesson, L.G. and Fanelli, G.M., eds, Recent advances in renal physiology and Pharmacology. Baltimore: University Press Park, 1974; 305–316.
-
(1974)
Recent advances in renal physiology and Pharmacology
, pp. 305-316
-
-
Hofmann, L.M.1
-
92
-
-
0016380105
-
Molecular modifications of anti-aldosterone compounds: effects on affinity of spirolactones for renal aldosterone receptors
-
Funder, J.W., Feldman, D., Highland, E. and Edelman, I.S. Molecular modifications of anti-aldosterone compounds: effects on affinity of spirolactones for renal aldosterone receptors. Biochem. Pharmacol. 1974; 23: 1493–1501.
-
(1974)
Biochem. Pharmacol
, vol.23
, pp. 1493-1501
-
-
Funder, J.W.1
Feldman, D.2
Highland, E.3
Edelman, I.S.4
-
93
-
-
0018865886
-
Importance of the lactonic ring in the activity of steroidal antialdosterones
-
Peterfalvi, M., Torelli, V., Foumex, R. and Rousseau, G. Importance of the lactonic ring in the activity of steroidal antialdosterones. Biochem. Pharmacol. 1980; 29: 353–357.
-
(1980)
Biochem. Pharmacol
, vol.29
, pp. 353-357
-
-
Peterfalvi, M.1
Torelli, V.2
Foumex, R.3
Rousseau, G.4
-
94
-
-
0017162594
-
Agonist and anti-mineralocorticoid activities of spirolactones
-
Sakauye, C. and Feldman, D. Agonist and anti-mineralocorticoid activities of spirolactones. Am. J. Physiol. 1976; 231: 93–97.
-
(1976)
Am. J. Physiol
, vol.231
, pp. 93-97
-
-
Sakauye, C.1
Feldman, D.2
-
95
-
-
0020432966
-
Relative potency and structure activity relationships of aldosterone antagonists in healthy man: correlation with animal experience
-
Mclnnes, G.J., Shelton, J.R., Ramsay, L.E., Harrison, I.R., Asbury, M.U., Clarke, J.M., Perkins, R.M. and Venning, G.R. Relative potency and structure activity relationships of aldosterone antagonists in healthy man: correlation with animal experience. Br. J. Clin. Pharmacol. 1982; 13: 331–339.
-
(1982)
Br. J. Clin. Pharmacol
, vol.13
, pp. 331-339
-
-
Mclnnes, G.J.1
Shelton, J.R.2
Ramsay, L.E.3
Harrison, I.R.4
Asbury, M.U.5
Clarke, J.M.6
Perkins, R.M.7
Venning, G.R.8
-
96
-
-
0017157318
-
SC 23992: radioreceptor assays for therapeutic and side effects
-
Funder, J.W., Mercer, J. and Hood, J. SC 23992: radioreceptor assays for therapeutic and side effects. Clin. Sci. Mol. Med. 1976; 51: 333S-3334S.
-
(1976)
Clin. Sci. Mol. Med
, vol.51
, pp. 333S-3334S
-
-
Funder, J.W.1
Mercer, J.2
Hood, J.3
-
97
-
-
0020688118
-
Binding and anti-mineralocorticoid activities of spirolactones in toad bladder
-
Rossier, B.C., Claire, M., Rafestin-Oblin, M.E., Geering, K., Gaggeler, H.P. and Corvol P. Binding and anti-mineralocorticoid activities of spirolactones in toad bladder. Am. J. Physiol. 1983; 244: C24-C31.
-
(1983)
Am. J. Physiol
, vol.244
, pp. C24-C31
-
-
Rossier, B.C.1
Claire, M.2
Rafestin-Oblin, M.E.3
Geering, K.4
Gaggeler, H.P.5
Corvol, P.6
-
98
-
-
0022630614
-
Separation of spironolactone and its biologically active sulfur-containing metabolites by high-performance liquid chromatography
-
Sherry, J.H., O’Donnell, J.P. and Colby, H.D. Separation of spironolactone and its biologically active sulfur-containing metabolites by high-performance liquid chromatography. J. Chromatogr. 1986; 374: 183–190.
-
(1986)
J. Chromatogr
, vol.374
, pp. 183-190
-
-
Sherry, J.H.1
O'Donnell, J.P.2
Colby, H.D.3
-
99
-
-
0019319966
-
Comparison of a single-dose and twice-a-day spironolactone therapy in mild hypertension
-
Ludbrook, A., Dynon, M., Mendelsohn, F.A.O. and Louis, WJ. Comparison of a single-dose and twice-a-day spironolactone therapy in mild hypertension. Med. J. Aust. 1980; 1: 124–125.
-
(1980)
Med. J. Aust
, vol.1
, pp. 124-125
-
-
Ludbrook, A.1
Dynon, M.2
Mendelsohn, F.A.O.3
Louis, W.J.4
-
100
-
-
0017641194
-
Gynecomastia and semen abnormalities induced by spironolactone in normal men
-
Caminos-Torres, R., Ma, L. and Snijder, PJ. Gynecomastia and semen abnormalities induced by spironolactone in normal men. J. Clin. Endocrinol. Metab. 1977; 45: 255–260.
-
(1977)
J. Clin. Endocrinol. Metab
, vol.45
, pp. 255-260
-
-
Caminos-Torres, R.1
Ma, L.2
Snijder, P.J.3
-
101
-
-
0017189578
-
Spironolactone and endocrine dysfunction
-
Loriaux, D.L. Spironolactone and endocrine dysfunction. Ann. Intern. Med. 1976; 85: 630–636.
-
(1976)
Ann. Intern. Med
, vol.85
, pp. 630-636
-
-
Loriaux, D.L.1
-
102
-
-
0018127454
-
Gynaecomastia induced in normal males by spironolactone
-
Huffman, D.H., Kampmann, J.P., Hignite, C.E. and Azanoff, D.L. Gynaecomastia induced in normal males by spironolactone. Clin. Pharmacol. Ther. 1978; 24: 465-473.
-
(1978)
Clin. Pharmacol. Ther
, vol.24
, pp. 465-473
-
-
Huffman, D.H.1
Kampmann, J.P.2
Hignite, C.E.3
Azanoff, D.L.4
-
103
-
-
0014959215
-
Spironolactone therapy and amenorrhea
-
Levitt, J.J. Spironolactone therapy and amenorrhea. J.A.M.A. 1970; 211: 2014–2015.
-
(1970)
J.A.M.A
, vol.211
, pp. 2014-2015
-
-
Levitt, J.J.1
-
104
-
-
0021909171
-
The effects of two doses of spironolactone serum androgen and anagen hair in hirsute women
-
Lobo, R.A., Shoupe, D., Serafini, P., Brinton, D. and Horton, R. The effects of two doses of spironolactone serum androgen and anagen hair in hirsute women. Fertil. Steril. 1985; 43: 200–205.
-
(1985)
Fertil. Steril
, vol.43
, pp. 200-205
-
-
Lobo, R.A.1
Shoupe, D.2
Serafini, P.3
Brinton, D.4
Horton, R.5
-
105
-
-
0018098679
-
SC 25152: a potent mineralaocorticoid antagonist with reduced affinity for the 5α-dihydrotestosterone receptor of human and rat prostate
-
Cutler, G.B., Pita, J.C., Rifka, S.M., Menard, R.H., Sauer, M.A. and Loriaux, D.L. SC 25152: a potent mineralaocorticoid antagonist with reduced affinity for the 5α-dihydrotestosterone receptor of human and rat prostate. J. Clin. Endocrinol. Metab. 1978;47: 171–175.
-
(1978)
J. Clin. Endocrinol. Metab
, vol.47
, pp. 171-175
-
-
Cutler, G.B.1
Pita, J.C.2
Rifka, S.M.3
Menard, R.H.4
Sauer, M.A.5
Loriaux, D.L.6
-
106
-
-
0020682933
-
The interaction of canrenone with oestrogen and progesterone receptors in human uterine cytosol
-
Fernandez, M.D., Carter, G.D. and Palmer, T.N. The interaction of canrenone with oestrogen and progesterone receptors in human uterine cytosol. Br. J. Clin. Pharmacol. 1983; 15: 95–101.
-
(1983)
Br. J. Clin. Pharmacol
, vol.15
, pp. 95-101
-
-
Fernandez, M.D.1
Carter, G.D.2
Palmer, T.N.3
-
107
-
-
0016693856
-
Interaction of spironolactone and digitalis with the 5α—dihydrotestosterone (DHT) receptor of rat ventral prostate
-
Pita, J.C., Lippman, M.E., Thompson, E.B. and Loriaux, D.L. Interaction of spironolactone and digitalis with the 5α—dihydrotestosterone (DHT) receptor of rat ventral prostate. Endocrinology 1975; 97: 1521–1527.
-
(1975)
Endocrinology
, vol.97
, pp. 1521-1527
-
-
Pita, J.C.1
Lippman, M.E.2
Thompson, E.B.3
Loriaux, D.L.4
-
108
-
-
0022621091
-
Gynaecomastia after spironolactone and potassium canrenoate
-
Bellati, G. and Ideo, G. Gynaecomastia after spironolactone and potassium canrenoate. Lancet 1986; 1: 626.
-
(1986)
Lancet
, vol.1
, pp. 626
-
-
Bellati, G.1
Ideo, G.2
-
109
-
-
0022007133
-
Disappearance of spironolactone-induced gynaecomastia during treatment with potassium canrenoate
-
Dupont, A. Disappearance of spironolactone-induced gynaecomastia during treatment with potassium canrenoate. Lancet 1985; 2: 731.
-
(1985)
Lancet
, vol.2
, pp. 731
-
-
Dupont, A.1
-
110
-
-
84915696337
-
Surveillance clinique et hormonale des traitements prolonges de 1'hypertension arterielle par les anti-aldosterones
-
Fromantin, M. Surveillance clinique et hormonale des traitements prolonges de 1'hypertension arterielle par les anti-aldosterones. Mises Jour. Cardiol. 1980; 19: 95–98.
-
(1980)
Mises Jour. Cardiol
, vol.19
, pp. 95-98
-
-
Fromantin, M.1
-
111
-
-
0022385128
-
In-vivo metabolites of spironolactone and potassium canrenoate: determination of potential anti-androgenic activity by a mouse kidney cytosol receptor assay
-
Armanini, D., Kartowiak, I., Goi, A., Mantero, F. and Funder, J.W. In-vivo metabolites of spironolactone and potassium canrenoate: determination of potential anti-androgenic activity by a mouse kidney cytosol receptor assay. Clin. Endocrinol. 1985; 23: 341–347.
-
(1985)
Clin. Endocrinol
, vol.23
, pp. 341-347
-
-
Armanini, D.1
Kartowiak, I.2
Goi, A.3
Mantero, F.4
Funder, J.W.5
-
112
-
-
84942232554
-
Kalium-Canrenoat- und Spironolacton-haltige Arzneimittel
-
Anonymus. Kalium-Canrenoat- und Spironolacton-haltige Arzneimittel. Deutsche Apotheker Zeitung 1986; 126 (36): VII–VIII.
-
(1986)
Deutsche Apotheker Zeitung
, vol.126
, Issue.36
, pp. VII-VIII
-
-
-
113
-
-
84942232554
-
Kalium-Canrenoat- und Spironolacton-haltige Arzneimittel
-
2312.
-
Anonymus. Kalium-Canrenoat- und Spironolacton-haltige Arzneimittel. Deutsche Apotheker Zeitung 1986; 126 (42): VIII–IX and 2312.
-
(1986)
Deutsche Apotheker Zeitung
, vol.126
, Issue.42
, pp. VIII-IX
-
-
-
114
-
-
84942232556
-
Spironolactone no longer to be used for treatment of hypertension
-
1988 January
-
Anonymous. Spironolactone no longer to be used for treatment of hypertension. The Pharmaceutical Journal 1988; January 9: 57.
-
(1988)
The Pharmaceutical Journal
, vol.9
, pp. 57
-
-
-
115
-
-
84942221123
-
In vitro metabolism of 14C-potassium canrenoate, 14C-spironolactone and 35S-spironolactone by rat liver microsomes
-
Hauswald, C.L., Cook, C.S., Koch, R.L. and Oppermann, J.A. In vitro metabolism of 14C-potassium canrenoate, 14C-spironolactone and 35S-spironolactone by rat liver microsomes. Pharmacologist 1986; 28: 212.
-
(1986)
Pharmacologist
, vol.28
, pp. 212
-
-
Hauswald, C.L.1
Cook, C.S.2
Koch, R.L.3
Oppermann, J.A.4
|