Randomized trial of ceftazidime versus placebo in the management of acute respiratory exacerbations in patients with cystic fibrosis

The Journal of Pediatrics

Volumn 111, Issue 6 PART 1, 1987, Pages 907-913

  Gold, Ronald ^a,b   Carpenter, Susan ^a,b   Heurter, Helen ^a,b   Corey, Mary ^a,b   Levison, Henry ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CEFTAZIDIME; PLACEBO;

ADOLESCENT; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CYSTIC FIBROSIS; DRUG EFFECT; FEMALE; HUMAN; LUNG; MALE; PATHOLOGY; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; BURKHOLDERIA CEPACIA; CLINICAL ARTICLE; CONTROLLED STUDY; PSEUDOMONAS AERUGINOSA;

ADOLESCENT; CEFTAZIDIME; CLINICAL TRIALS; COMPARATIVE STUDY; CYSTIC FIBROSIS; FEMALE; HUMAN; LUNG; MALE; PLACEBOS; RANDOM ALLOCATION; SUPPORT, NON-U.S. GOV'T;

EID: 0023491564     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-3476(87)80217-2     Document Type: Article

References (42)

1. Cystic fibrosis
2. The pathogenesis and treatment of pulmonary infections in patients with cystic fibrosis
3. Infection in patients with cystic fibrosis
4. Celiac syndrome IV Chemotherapy of infections of the respiratory tract associated with cystic fibrosis of the pancreas observations with penicillin and drugs of the sulfonamide group with special reference to penicillin acrosol
5. Aureomycin therapy in the pulmonary involvement of pancreatic fibrosis (mucoviscidosis)
6. Treatment of pulmonary infections in patients with cystic fibrosis: a comparative study of ticarcillin and gentamicin
7. Amikacin therapy of exacerbations of Pseudomonas aeruginosa infections in patients with cystic fibrosis
8. Chemotherapy of chronic infections with mucoid Pseudomonas aeruginosa in lower airways of patients with cystic fibrosis
9. Antibiotic treatment of chronic Pseudomonas aeruginosa infection in cystic fibrosis patients
10. A double-blind controlled trial of anti-Pseudomonas chemotherapy of acute respiratory exacerbations in patients with cystic fibrosis
11. Comparative study of the antibacterial activity of amikacin and tobramycin during Pseudomonas pulmonary infection in patients with cystic fibrosis
12. Ceftazidime alone and in combination in patients with cystic fibrosis: lack of efficacy in treatment of severe respiratory infections caused byPseudomonas cepacia
13. Treatment of chronic Pseudomonas aeruginosa infection in cystic fibrosis patients with ceftazidime and tobramycin
14. Piperacillin and tobramycin in the treatment of Pseudomonas lung infections in cystic fibrosis
15. Efficacy of inhaled tobramycin in the treatment of pulmonary exacerbations in children with cystic fibrosis
16. Cefsulodin sodium therapy in cystic fibrosis patients
17. Treatment of lower respiratory tract infections due to Pseudomonas aeruginosa in patients with cystic fibrosis
18. Comparison of cefoperazone sodium vs methicillin, ticarcillin, and tobramycin in treatment of pulmonary exacerbations in patients with cystic fibrosis
19. Ceftazidime therapy in patients with cystic fibrosis and multiply-drug-resistant Pseudomonas
20. Imipenem/cilastatin in acute pulmonary exacerbations of cystic fibrosis
21. Treatment of lower respiratory tract infections due to Pseudomonas aeruginosa in patients with cystic fibrosis
22. Immediate and prolonged clinical efficacy of ceftazidime versus ceftazidime plus tobramycin in chronic Pseudomonas infection in cystic fibrosis
23. Comparison of piperacillin vs. ticarcillin plus tobramycin in the treatment of acute pulmonary exacerbations of cystic fibrosis
24. Oral ciprofloxacin compared with conventional intravenous treatment for Pseudomonas aeruginosa infection in adults with cystic fibrosis
25. A placebocontrolled trial of cephalexin therapy in the ambulatory management of patients with cystic fibrosis
26. Frequent antibiotic therapy improves survival of cystic fibrosis patients with chronic Pseudomonas aeruginosa infection
27. Antibiotic prophylaxis in cystic fibrosis: inhaled cephaloridine as an adjunct to oral cloxacillin
28. Aerosol carbenicillin and gentamicin treatment of Pseudomonas aeruginosa infection in patients with cystic fibrosis
29. Nebulized gentamicin in children and adolescents with cystic fibrosis
30. Inhaled antibiotics in cystic fibrosis: is there a therapeutic effect
31. Is anti-Pseudomonas therapy warranted in acute respiratory exacerbations in children with cystic fibrosis?
32. Clinical and bacteriological responses to three antibiotic regimens for acute exacerbations of cystic fibrosis: ticarcillin-tobramycin,azlocillin-tobramycin, azlocillin-placebo
33. Controlled trial of ceftazidime vs. ticarcillin and tobramycin in the treatment of acute respiratory exacerbations in patients with cystic fibrosis
34. Acute pulmonary exacerbations in cystic fibrosis
35. Management of acute pulmonary exacerbations in cystic fibrosis: a critical appraisal
36. Antibiotic therapy in cystic fibrosis: evaluation of clinical trials
37. Ceftazidime disposition in acute and stable cystic fibrosis
38. Pseudomonas cepacia infection in cystic fibrosis: an emerging problem
39. Importance of viruses and Legionella pneumophila in respiratory exacerbations of young adults with cystic fibrosis
40. Association of respiratory viral infections with pulmonary deterioration in patients with cystic fibrosis
41. Cough versus chest physiotherapy: a comparison of the acute effects on pulmonary function in patients with cystic fibrosis
42. Immediate and long-term effects of chest physiotherapy in patients with cystic fibrosis