Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

Nature

Volumn 330, Issue 6149, 1987, Pages 662-664

  Tracey, Kevin J ^a,c   Fong, Yuman ^a   Hesse, David G ^a   Manogue, Kirk R ^c   Lee, Annette T ^c   Kuo, George C ^b   Lowry, Stephen F ^a   Cerami, Anthony ^c  

^a WEILL CORNELL MEDICAL CENTER   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; BACTEREMIA; BLOOD PRESSURE; ESCHERICHIA COLI; HEART OUTPUT; HYPOTENSION; NONHUMAN; PRELIMINARY COMMUNICATION;

ANIMAL; ANTIBODIES, MONOCLONAL; BLOOD PRESSURE; CARDIAC OUTPUT; CATECHOLAMINES; GLUCAGON; IMMUNIZATION, PASSIVE; IMMUNOLOGIC TECHNIQUES; LEUKOCYTE COUNT; PAPIO; SEPTICEMIA; SHOCK, SEPTIC; TUMOR NECROSIS FACTOR;

EID: 0023491364     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/330662a0     Document Type: Article

References (27)

1. Kreger, B. E. W., Craven, D. E. & McCabe, W. R., Am, J. Med. 68, 344-355 (1980).
2. Ziegler, E. J. et al New Engl J. Med. 307, 1225-1230 (1982).
3. Gilbert, R. P. Physiol Rev. 40. 245-279 (1960).
4. Beutler, B A., Cerami, A. Nature 320. 584-588 (1986)
5. Beutler, B. A, Cerami, A. New Engl J Med 316, 379-385 (1987).
6. Tracey, K J., Lowry, S. F. … Cerami, A. in TNF and Related Cyiotoxiru. CIBA Found. Symp. 131, 88-108 (Wiley, London. 1987).
7. Tracey, K. J., Lowry, S. F. & Cerami, A. J. infeet. Dis. (in the press).
8. Beutler, B., Milsark, I. W. & Cerami, A. J. Immun. 135, 3972-3977 (1985).
9. Tracey, K. J. et alScience 234, 470-474 (1986).
10. Tracey, K. J. et al Surg. gynecol. Obnet. 164, 415-422 (1987).
11. Beutler, B., Milsark, I. W. & Cerami, A. Science 229. 869-871 (1985).
12. Cryer, P. E., Herman, C. M. & Sode, J. Ann. Surg. 174, 91-100 (1971).
13. CoaJion, J. J. Hinshaw, L. B. Guenter, C. A., Burrel, E. L. & Greenfield, L. J. lab. Invest. 32, 561-569 (1975).
14. Hesse, D. G. et al. Surg. gynea. il Obstet (in the press).
15. Lowry, S. F. in Advances in Host Defence Mechanisms Vol 6 (ed, Guilin, J. I. & Fauci, A. S.) 169-190 (Raven, New York, 1986).
16. McCabe, W. R New Engl J. Med 288, 21-23 (1973).
17. Dinarclto, C. A et al. J. exp Med 163, 1433-1450 (1986)
18. Darius, H., Lefer, D. J., Smith, J. B. & Lefer, A M Science 232, 58-60 (1986).
19. Chang, S. W., Fedderaen, C. O., Henion, P. M. & Voelkel, N. F. J. Clin Incest. 79, 1498-1509 (1987).
20. Scuderi, P., et al. Lancet 2. 1364-1365 (1986).
21. Tracey, K. I. et al Surg. horum 37, 13-15 (1986).
22. Waage, A., Halstcnsen, A. & Espevik, T. Lancet 1, 355-357 (1987).
23. Pool, J. L. Surg gynecol. Obstet 132, 1-9 (1971).
24. Parham, P J. Immun 131, 2895-2899 (1983).
25. Peters, P. M. et al J. Immun 137, 2592-2598 (1986).
26. Carswell, E. A., et al Proc. natn. Aiad. Sci. U. S. A. 72, 3666-3670 (1975).
27. Aquilar-Parada, A., Eisemraut, E. M. & Unger, R. H. Diabetes 18, 717-723 (1969).