An In-Vitro Comparison of the Intraphagocytic Bioactivity of Erythromycin and Roxithromycin

Journal of Antimicrobial Chemotherapy

Volumn 20, Issue , 1987, Pages 57-68

  Anderson, R ^a   Van Rensburg, C E J ^a   Joone G ^a  

^a UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROMYCIN; ERYTHROMYCIN C 14; ROXITHROMYCIN; UNCLASSIFIED DRUG;

DRUG BINDING; DRUG SENSITIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; LEGIONELLA MICDADEI; LISTERIA MONOCYTOGENES; MINIMUM INHIBITORY CONCENTRATION; NEUTROPHIL; NONHUMAN; STAPHYLOCOCCUS AUREUS;

BACTERIA; COMPARATIVE STUDY; ERYTHROMYCIN; HUMAN; LEUCOMYCINS; MICROBIAL SENSITIVITY TESTS; NEUTROPHILS; SODIUM FLUORIDE; SPECTROMETRY, FLUORESCENCE;

EID: 0023481182     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/20.suppl_B.57     Document Type: Article

References (20)

1. Anderson, R., Joone G. 8 Van Rensburg, C. E. J. (1986). An in vitro investigation of the intracellular bioactivity of amoxycillin, clindamycin and erythromycin for Staphylococcus aureus. Journal of Infectious Diseases 153, 593-600.
2. Bassler, M., Just, H. J., Richter, A., Zeller, H. 8 Darchner, F. (1984). Antibakterielle Aktivitat von Gindamycin und Lincomycin in Bouillon, Serum und in Kombination mit polymorphkernigen Granulozyten gegen Staphylococcus aureus und Staphylococcus epidermidis. Infection 12, 280-5.
3. Daschner, F. D. (1985). Antibiotics and host defence with special reference to phagocytosis by polymorphonuclear leucocytes. Journal of Antimicrobial Chemotherapy 16, 135-42.
4. Easmon, C. S. F. 8 Crane, J. P. (1984). Cellular uptake of clindamycin and lincomycin. British Journal of Experimental Pathology 65, 725-30.
5. Eltahawy, A. T. (1983). The penetration of mammalian cells by antibiotics. Journal of Antimicrobial Chemotherapy 11, 293-8.
6. Ezer, G. 8 Soothill, J. F. (1974). Intracellular bactericidal effects of rifampin in both normal and chronic granulomatous disease polymorphs. Archives of Diseases of Childhood 49, 463-6.
7. Horwitz, M. A. (1983). The Legionnaire’s disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes. Journal of Experimental Medicine 158, 2108-26.
8. Horwitz, M. A. 8 Silverstein, S. C. (1983). Intracellular multiplication of Legionnaire’s disease bacteria (Legionella pneumophila) in human monocytes is reversibly inhibited by erythromycin and rifampicin. Journal of Clinical Investigation 71, 15-26.
9. Johnson, J. D., Hand, W. L., Francis, J. B., King-Thompson, M. 8 Corwin, R. W. (1980). Antibiotic uptake by alveolar macrophages. Journal of Laboratory and Clinical Medicine 95, 429-39.
10. Klempner, M. S. 8 Styrt, B. (1981). Clindamycin uptake by neutrophils. Journal of Infectious Diseases 144, 472-9.
11. Mandell, G. L. 8 Vest, T. K. (1972). Killing of intraleukocytic Staphylococcus aureus by rifampin: In vitro and in vivo studies. Journal of Infectious Diseases 125, 486-90.
12. Matzer, Y., Brass, L. M., McMurrich, B. J., Peters, W. A., Schwartz, J. A. 8 Babior, B. M. (1982). Expression of a chronic granulomatous disease-like defect by fluoride-exhausted neutrophils. Blood 60, 822-6.
13. Miller, M. F., Martin, J. R., Johnson, P., Ulrich, J. T., Rdzok, E. J. 8 Billing, P. (1984). Erythromycin uptake and accumulation by human polymorphonuclear leukocytes and efficacy of erythromycin in killing ingested Legionella pneumophila. Journal of Infectious Diseases 149, 714-8.
14. Prokesch, R. C. 8 Hand, W. L. (1982). Antibiotic entry into human polymorphonuclear leukocytes. Antimicrobial Agents and Chemotherapy 21, 373-80.
15. Prozanski, W., Saito, S. 8 Nitzan, D. W. (1983). The influence of lysostaphin on phagocytosis, bactericidal activity and chemotaxis of human polymorphonuclear cells. Journal of Laboratory and Clinical Medicine 102, 298-305.
16. Quie, P. G., White, J. G., Holmes, B. 8 Good, R. A. (1967). In vitro bactericidal capacity of polymorphonuclear leucocytes: Diminished activity in chronic granulomatous disease in childhood. Journal of Clinical Investigation 46, 668-79.
17. Rodgers, F. G. 8 Elliot, T. S. J. (1984). Antibiotic killing of legionella. Lancet i, 683-4.
18. Silva, J., Dembinski, S. 8 Schaberg, D. (1983). Effects of subinhibitory antibiotics on bactericidal activity of chronic granulomatous disease granulocytes in vitro. Journal of Antimicrobial Chemotherapy 12, Suppl. C, 21-7.
19. Smith, D. L. 8 Rommel, F. (1977). A rapid micro-method for the simultaneous determination of phagocytic-microbicidal activity of human peripheral blood leukocytes in vitro. Journal of Immunological Methods 17, 241-7.
20. Vosbeck, K., James, P. R. 8 Zimmermann, W. (1984). Antibiotic action on phagocytosed bacteria measured by a new method for determining viable bacteria. Antimicrobial Agents and Chemotherapy 25, 735-41.