‘Low-dose’ corticosteroid prophylaxis against fat embolism

Journal of Trauma - Injury, Infection and Critical Care

Volumn 27, Issue 10, 1987, Pages 1173-1176

  Kallenbach, Jeremy ^a   Lewis, M ^a,b   Zaltzman, M ^a   Feldman, C ^a   Orford, A ^a   Zwi, S ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLPREDNISOLONE;

EMBOLISM PREVENTION; FAT EMBOLISM; FRACTURE; HUMAN; LEG INJURY; MAJOR CLINICAL STUDY;

ADULT; ANOXEMIA; CLINICAL TRIALS; COMPARATIVE STUDY; EMBOLISM, FAT; FEMALE; FEMORAL FRACTURES; FIBULA; FRACTURES; HUMAN; MALE; METHYLPREDNISOLONE; TIBIAL FRACTURES;

EID: 0023473286     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/00005373-198710000-00013     Document Type: Article

References (19)

1. Alho, A., Saikku, K., Eerola, P., et al.: Corticosteroids in patients with a high risk of fat embolism syndrome. Surg. Gynecol. Obstet., 147: 358-362, 1978.
2. Ashbaugh, D. G., Petty, T. L.: The use of corticosteroids in the treatment of respiratory failure associated with massive fat embolism. Surg. Gynecol. Obstet., 123: 493-500, 1966.
3. Benatar, S. R., Ferguson, A. D., Goldschmidt, R. B.: Fat embo-lism-Some clinical observations and a review of controversial aspects. Quart. J. Med. 41: 85-98, 1972.
4. Dale, D. C, Petersdorf, R. G.: Corticosteroids and infectious dis-eases. Med. Clin. North Am. 57: 1277-1287, 1973.
5. Fauci, A. S., Dale, D. C, Balow J. E.: Glucocorticosteroid therapy:Mechanisms of action and clinical considerations. Ann. Intern. Med., 84: 304-315, 1976.
6. Hammerschmidt, D. E., White,.J. G., Craddock, P. R., et al.:Corticosteroids inhibit complement-induced granulocyte aggregation: A possible mechanism for their efficacv in shock states. J. Clin. Invest., 63: 798-803, 1979.
7. Kanarek, D. J., Goldman, H. I., Zwi, S.: Arterial oxygen tension values in normal adults at an altitude of 1763 metres. S. Afr. Med. J. 46: 315-317, 1972.
8. Lapin, L. L.: Statistics: Meaning and Method. New York, Harcourt, Brace,.lovanovich, 1975, pp. 420-446.
9. Lepisto, P., Alho, A.: Diagnostic features of the fat embolism syndrome. Acta Chir. Scand. 141: 245-250, 1975.
10. McCarthy, B., Mammen, E., Leblanc, L. P., et al.: Subclinical fat embolism: A prospective study of 50 patients with extremity fractures. J. Trauma, 13: 9-16, 1973.
11. Pollak, R., Myers, R. E. M.: Early diagnosis of the fat embolism syndrome. J. Trauma. 18: 121-123, 1978.
12. Rinaldo,.J. E., Rogers, R. M.: Adult respiratory-distress syndrome:Changing concepts of lung injury and repair. N. Engl. J. Med., 306: 900-909, 1982.
13. Schonfeld, S. A., Ploysongsang, Y., Dilisio, R., et al.: Fat embolism prophylaxis with corticosteroids. Ann. Intern. Med., 99: 438-443, 1983.
14. Shier, M. R., Wilson, R. F., James, R. E., et al.: Fat embolism prophylaxis: A study of four treatment modalities. J. Trauma, 17: 621-629, 1977.
15. Stoltenberg, J. J., Guslilo, R. B.: The use of methylprednisolone and hypertonic glucose in the prophylaxis of fat embolism svn-drome. Clin. Orthop., 143: 211-221,1979.
16. Tachakra, S. S., Sevitt, S.: Hypoxaemia after fractures. J. Rone Jt. Surg., 57B: 197-203, 1975.
17. Tate, R. M. Repine, J. E.: Neutrophils and the adult respiratory distress syndrome. Am. Rev. Reap. Ms., 128: 552-559, 1983.
18. Ulmer, W. T., Reichel, G., Nolte, D.: In Die lungenfunktion. Physiologic und pathophysiologic methodik. Stuttgart, Georg Thieme Verlag, 1970.
19. Weinstein, I,., Barza, M. A.: Gas gangrene. N. Engl. J. Med., 289: 1129-1131,1973.