Collagen Synthesis and Degradation In Vivo. Evidence for Rapid Rates of Collagen Turnover with Extensive Degradation of Newly Synthesized Collagen in Tissues of the Adult Rat

Topics in Catalysis

Volumn 7, Issue 2, 1987, Pages 93-104

  McAnulty, Robin J ^a   Laurent, Geoffrey J ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

collagen; degradation; synthesis

Indexed keywords

COLLAGEN; HYDROXYPROLINE; PROCOLLAGEN; PROLINE;

ANIMAL; ARTICLE; BIOSYNTHESIS; KINETICS; LEWIS RAT; MALE; METABOLISM; RAT; TISSUE DISTRIBUTION;

ANIMALS; COLLAGEN; HYDROXYPROLINE; KINETICS; MALE; PROCOLLAGEN; PROLINE; RATS; RATS, INBRED LEW; TISSUE DISTRIBUTION;

EID: 0023359580     PISSN: 0174173x     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0174-173X(87)80001-8     Document Type: Article

References (39)

1. Collagen degradation and the response to parathyroid extract in the intact rhesus monkey
2. Studies in vivo on the biosynthesis of collagen and elastin in ascorbic acid-deficient guinea-pigs
3. Lysosomal function in the degradation of defective collagen in cultured lung fibroblasts
4. Intracellular degradation of newly synthesized collagen
5. Fibroblasts degrade newly synthesized collagen within the cell before secretion
6. Formation of Proline Metabolites in Chick Embryo Bone: Interference with the Measurement of Free Hydroxyproline by Ion-Exchange Chromatography
7. Time Lag in the Secretion of Collagen by Matrix-Free Tendon Cells and Inhibition of the Secretory Process by Colchicine and Vinblastine
8. Biosynthesis of Cartilage Procollagen
9. Biosynthesis of Basement Membrane Collagen in Embryonic Chick Lens
10. 3H-labelling
11. 14C-proline in rats with and without administration of prednisolone
12. Urinary excretion of hydroxyproline in health and disease
13. Metabolism of Human Clq
14. Collagen like Fragments: Excretion in urine of patients with Paget's disease of bone
15. 3H]proline
16. Collagen metabolism in the normal lung
17. Protein Metabolism during Bleomycin-induced Pulmonary Fibrosis in Rabbits
18. 3H] proline specific activity following chloramine-T oxidation
19. Changes in collagen synthesis and degradation during skeletal muscle growth
20. Isotopic studies on urinary hydroxyproline as evidence for rapidly catabolized forms of collagen in the young rat
21. Synthesis and turnover of collagen precursors in rabbit skin
22. 14 in Biological Materials
23. Isotopic studies on collagen degradation and the urine excretion of hydroxyproline
24. A Simple Technique for Measuring the Specific Activity of Labeled Hydroxyproline in Biological Materials
25. The biosynthesis of collagen and its disorders (I)
26. The Complement System
27. Intracellular degradation of newly synthesized collagen
28. Response of rat connective tissues to streptozotocin-diabetes. Tissue-specific effects on collagen metabolism
29. Extensive degradation of recently synthesized collagen in gingiva of normal and streptozotocin-induced diabetic rats
30. The in vivo fractional rate of gingival collagen production in non-diabetic and diabetic rats
31. A new approach to assessing collagen turnover by using a micro-assay. A highly efficient and rapid turnover of collagen in rat periodontal tissues
32. A comparison of the rates of synthesis and turnover of collagen and non-collagen proteins in adult periodontal tissues and skin using a microassay
33. Nonenzymatic hydroxylations of proline and lysine by reduced oxygen derivatives
34. Collagen metabolism during right ventricular hypertrophy following induced lung injury