Column liquid chromatography of methotrexate and its metabolites using a post-column photochemical reactor and fluorescence detection

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 419, Issue C, 1987, Pages 213-223

  Šalamoun, Jaroslav ^a   Smrž, Miloslav ^a   Kiss, Franktišek ^a   Šalamounová, Anna ^a  

^a Research Institute of Pure Chemicals Lachema Karásek 28 621 33 Brno Czechoslovakia ^*

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; METHOTREXATE;

BLOOD AND HEMOPOIETIC SYSTEM; DRUG ANALYSIS; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG URINE LEVEL; FLUORESCENCE; HUMAN; LIQUID CHROMATOGRAPHY; METHODOLOGY; PLASMA; URINE;

BUFFERS; CHROMATOGRAPHY, LIQUID; HUMAN; HYDROGEN PEROXIDE; HYDROGEN-ION CONCENTRATION; METHOTREXATE; OXYGEN; PHOTOCHEMISTRY; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0023275196     PISSN: 03784347     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-4347(87)80279-7     Document Type: Article

References (11)

1. Determination of methotrexate and its metabolites 7-hydroxymethotrexate and 2,4-diamino-N10-methylpteroic acid in biological fluids by liquid chromatography with fluorimetric detection