POTENTIAL ANALGESIC CONTRIBUTION FROM MORPHINE-6-GLUCURONIDE IN CSF

The Lancet

Volumn 330, Issue 8569, 1987, Pages 1207-1208

  Hand, C W ^a   Blunnie, W P ^b   Claffey, L P ^b   Mcshane, A J ^b   Mcquay, H J ^c   Moore, R A ^a,d  

^a DPC European Research Institute ^*

^b MATER MISERICORDIAE UNIVERSITY HOSPITAL   (Ireland)

^c Abingdon Hospital   (United Kingdom)

^d Oxford Regional Pain Relief Unit   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MORPHINE;

ANALGESIA; HUMAN; KIDNEY; KIDNEY FAILURE; SHORT SURVEY; THERAPY;

ANALGESIA; COMPARATIVE STUDY; HUMAN; MORPHINE; MORPHINE DERIVATIVES;

EID: 0023272780     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(87)91341-9     Document Type: Letter

References (9)

1. Analgesic effects of morphine glucuronides
2. Morphine-6-glucuronide has high affinity for the opioid receptor
3. Metabolism of narcotics
4. Morphine intoxication in renal failure the role of morphine-6-glucuronide
5. Analysis of morphine and its major metabolites by differential radioimmunoassay
6. Determination of morphine, morphine-3-glucuromde and (tentatively) morphine-6-glucuronide in plasma and urine ion-pair high performance liquid chromatography
7. Morphine and its 3- and 6-glucuromdes in plasma and urine during chronic oral administration in cancer patients
8. Biochemical basis for analgesic activity of morphine-6-glucuronide I: Penetration of morphine-6-glucuronide in the brain of rats
9. Spinal fluid kinetics of morphine and heroin