A ferriprotoporphyrin IX-chloroquine complex promotes membrane phospholipid peroxidation A possible mechanism for antimalarial action

FEBS Letters

Volumn 223, Issue 2, 1987, Pages 251-254

  Sugioka, Yumiko ^a   Suzuki, Mamoru ^a   Sugioka, Katsuaki ^a,b   Nakano, Minoru ^a,b  

^a GUNMA UNIVERSITY   (Japan)

^b GUNMA UNIVERSITY   (Japan)

Author keywords

Chloroquine; Ferriprotoporphyrin IX; Lipid peroxidation

Indexed keywords

CHLOROQUINE; HEMATIN; MEMBRANE PHOSPHOLIPID;

DRUG MECHANISM; LIPID PEROXIDATION;

CHLOROQUINE; FATTY ACIDS; FERRIC COMPOUNDS; FERROUS COMPOUNDS; HEME; HEMIN; KINETICS; LIPID PEROXIDES; OXIDATION-REDUCTION; PHOSPHOLIPIDS; SPECTRUM ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0023272746     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(87)80299-5     Document Type: Article

References (14)

1. Unsaturated lipide oxidation catalyzed by hematin compounds.