Activation of Human Monocyte Tumoricidal Activity by C-reactive Protein

Cancer Research

Volumn 47, Issue 15, 1987, Pages 3959-3963

  Deodhar, Sharad D ^b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CENTRAL DUPAGE HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN;

IN VITRO STUDY; MONOCYTE; PRIORITY JOURNAL;

ASTROCYTES; ASTROCYTOMA; C-REACTIVE PROTEIN; CARCINOMA, RENAL CELL; CELL LINE; CYTOTOXICITY TESTS, IMMUNOLOGIC; CYTOTOXICITY, IMMUNOLOGIC; FIBROBLASTS; HUMAN; KIDNEY NEOPLASMS; MELANOMA; MONOCYTES; PHOSPHORYLCHOLINE; SUPEROXIDES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TETRADECANOYLPHORBOL ACETATE;

EID: 0023270609     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Abemethy, T. J., and Avery, O. T. The occurrence during acute infections of a protein not normally present in the blood. I. Distribution of the reactive protein in patients sera and the effect of calcium on the flocculation reaction with C-polysaccharide of pneumococcus. J. Exp. Med., 73:173-182,1941.
2. Gewurz, H., Mold, C., Siegel, J., and Fiedel, B. C-Reactive protein and the acute phase response. Adv. Intern. Med., 27:345-372, 1982.
3. Tillett, W. S., and Francis, T., Jr. Serological reactions in pneumonia with a nonprotein fraction from pneumococcus. J. Exp. Med., 52: 561–571, 1930.
4. Pepys, M. G., Dash, A. C., Fletcher, T. C., Richardson, N., Munn, E., and Feinstein, A. Analogues in other mammals and in fish of human plasma proteins, CRP and amyloid P component. Nature (Lond.), 273: 168–170, 1978.
5. Claus, D., Siegel, J., Petras, K., Osmand, A., and Gewurz, H. Interactions of CRP with the first component of human complement. J. Immunol., 119: 187–192, 1977.
6. James K., Hansen, B., and Gewurz, H. Binding of C-reactive protein to human lymphocytes. I. Requirement for a binding specificity. J. Immunol., 127: 2539-2545,1981.
7. James, K., Hansen, B., and Gewurz, H. Binding of C-reactive protein to human lymphocytes. II. Interaction with a subset of cells bearing the Fc receptor. J. Immunol., 127: 2546–2550, 1981.
8. Mold, C., Du Clos, T. W., Nakayama, S., Edwards, K. M., and Gewurz, H. C-Reactive protein reactivity with complement and effects on phagocytosis. Ann. NY Acad. Sci., 389:251-262, 1982.
9. Mortensen, R. F., Osmand, A. P., Lint, T. F., and Gewurz, H. Interaction of C-reactive protein with lymphocytes and monocytes: complement dependent adherence and phagocytosis. J. Immunol., 117: 774-781,1976.
10. Vetter, M. L., Gewurz, H., and Baum, L. L. The effects of C-reactive protein on human cell-mediated cytotoxicity. J. Leuk. Biol., 39: 13–25, 1986.
11. Deodhar, S. D., James, K., Chiang, T., Edinger, M., and Barna, B. P. Human C-reactive protein (CRP) inhibits lung metastases and prolongs survival of mice bearing a malignant fibrosarcoma. Cancer Res., 42: 5084–5088, 1982.
12. Gautam, S., Barna, B., Chiang, T., Pettay, J., and Deodhar, S. Use of resealed erythrocytes as delivery system for C-reactive protein (CRP) to generate macrophage mediated tumoricidal activity. J. Biol. Response Modif., in press, 1987.
13. Barna, B. P., Deodhar, S. D., Gautam, S., Yen-Lieberman, B., and Roberts, D. Macrophage activation and generation of tumoricidal activity by liposome-associated human C-reactive protein. Cancer Res., 44: 305–310, 1984.
14. Barna, B. P., Chou, S. M., Jacobs, B., Ransohoff, R. M., Hahn, J. F., and Bay, J. W. Enhanced DNA synthesis of human glial cells exposed to human leukocyte products. J. Neuroimmunol., 10: 151–158, 1985.
15. Kleinerman, E. S., Schroit, A. J., Fogler, W. E., and Fidler, I. J. Tumoricidal activity of human monocytes activated in vitro by free and liposome-encap-sulated human lymphokines. J. Clin. Invest., 72:304-315, 1984.
16. Pick, E., and Mizel, D. Rapid microassays for the measurement of superoxide and hydrogen peroxide production by cells in culture using an automatic enzyme immunoassay reader. J. Immunol. Methods, 46: 211–226, 1981.
17. Herberman, R. B. Natural killer cell activity and antibody-dependent cell-mediated cytotoxicity. In: N. R. Rose, H. Friedman, and J. L. Fahey (eds.), Manual of Clinical Laboratory Immunology, Ed. 3, pp. 308–314. Washington, DC: American Society for Microbiology, 1986.
18. Lanier, L. L., Le, A. M., Phillips, J. H., Warner, N. L., and Babcock, G. F. Subpopulations of human natural killer cells defined by expression of the Leu 7 (HNK-1) and Leu-11 (NK-15) antigens. J. Immunol., 131:1789-1796, 1983.
19. Volanakis, J. E., and Kaplan, M. H. Specificity of C-reactive protein for choline phosphate residues of pneumococcal C-polysaccharide. Proc. Soc. Exp. Biol. Med., 136:612-614, 1971.
20. Morrison, D. C., and Jacobs, D. M. Binding of Polymyxin B to the Lipid A portion of bacterial lipopolysaccharides. Immunochemistry, 13: 813–818, 1976.
21. Zahedi, K., and Mortensen, R. F. Macrophage tumoricidal activity induced by human C-reactive protein. Cancer Res., 46: 5077–5083, 1986.
22. de Beer, F. C., Soutar, A. K., Baltz, M. L., Trayner, I. M., Feinstein, A., and Pepys, M. B. Low density lipoprotein and very low density lipoprotein are selectively bound by aggregated C-reactive protein. J. Exp. Med., 156: 230–242, 1982.
23. Pepys, M. B., Rowe, I. F., and Baltz, M. I. C-reactive protein: binding to lipids and lipoproteins. Int. Rev. Exp. Pathol., 27:83-111, 1985.
24. Rowe, I. F., Soutar, A. K., Trayner, I. M., Thompson, G. R., and Pepys, M. B. Circulating human C-reactive protein binds very low density lipoproteins. Clin. Exp. Immunol., 58: 237–244, 1984.
25. Kleinerman, E. S., and Herberman, R. B. Tumoricidal activity of human monocytes: evidence for cytolytic function distinct from that of NK cells. J. Immunol., 133:4-6, 1984.
26. Baum, L. L., James, K. K., Glaviano, R. R., and Gewurz, H. Possible role for C-reactive protein in the human natural killer cell response. J. Exp. Med., 757:303-311, 1983.
27. Kleinerman, E. S., Ceccorelli, L. M., Bonvini, E., Zicht, R., and Gallin, J. I. Lysis of tumor cells by human blood monocytes by a mechanism independent of activation of the oxidative burst. Cancer Res., 45:2058-2064, 1985.