Sex steroid effects on extrahypothalamic CNS. II. Progesterone, alone and in combination with estrogen, modulates cerebellar responses to amino acid neurotransmitters

Brain Research

Volumn 422, Issue 1, 1987, Pages 52-62

  Smith, Sheryl S ^a   Waterhouse, Barry D ^a   Woodward, Donald J ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Anxiolytic; Cerebellar Purkinje cell; Estrogen; Glutamate; Neuromodulation; Neuronal responsiveness; Progesterone; Aminobutyric acid

Indexed keywords

4 AMINOBUTYRIC ACID; ESTROGEN; GLUTAMIC ACID; PROGESTERONE;

ANIMAL EXPERIMENT; CENTRAL NERVOUS SYSTEM; CEREBELLUM; NONHUMAN; PURKINJE CELL; RAT; TOPICAL DRUG ADMINISTRATION;

ACTION POTENTIALS; ANIMAL; ANISOMYCIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; ESTRADIOL; FEMALE; GAMMA-AMINOBUTYRIC ACID; GLUTAMATES; GLUTAMIC ACID; INJECTIONS, INTRAVENOUS; IONTOPHORESIS; PROGESTERONE; PURKINJE CELLS; RATS; RATS, INBRED STRAINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023264849     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(87)90539-7     Document Type: Article

References (33)

1. Estrogen and progesterone in plasma in relation to premenstrual tension
2. Cell membrane, a target for steroid hormones
3. Correlation of luteinizing hormone surges with estrogen nuclear and progestin cytosol receptors in the hypothalamus and pituitary gland. I. and II
4. A study of the interaction between progesterone and membrane lipids
5. Interactions of Flurazepam with glutamate evoked excitatory responses of cerebellar Purkinje neurons
6. Progesterone and the premenstrual syndrome: a double blind crossover trial
7. Interaction of norepinephrine with cerebellar activity evoked by moss and climbing fibers
8. An improved constant current source for microiontophoretic drug application studies
9. Benzodiazepines and central inhibitory mechanisms
10. Progesterone metabolism in the pineal, brainstem, thalamus and corpus callosu of the female rat
11. A rapid and simple procedure for chronic cannulation of the rat jugular vein
12. Experimental and clinical data indicating the psychotropic properties of progestogens
13. 3]5-alpha-dihydroprogesterone by rat brain and pituitary and effects of estradiol and time: tissue concentration of progesterone itself or specific metabolites?
14. Effect of progesterone and its 17 alpha-hydroxyl derivative on human erythrocyte membrane
15. The plasma membrane of rat hypothalamic tissue is the primary site for progesterone stimulatory action on LHRH release
16. Iontophoretic studies of neurones in the mammalian cerebral cortex
17. Progestin receptors in rat brain: distribution and properties of cytoplasmic progestin-binding sites
18. Progesterone and estrogens in rat brain: modulation of GABA receptor activity
19. Role of the female gonadal hormones in the CNS: clinical and experimental aspects
20. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor
21. Epilepsy, sex hormones, and antiepileptic drugs
22. Gonadal steroid action on the brain: neurochemistry and neuropharmacology
23. Hypothalamic protein synthesis essential for the activation of the lordosis reflex in the female rat
24. Metabolic clearance rat of progesterone: comparison between ovariectomized, pregnant, pseudopregnant and deciduoma-bearing pseudopregnant rats
25. Effect of ovarian hormones on conflict behavior
26. Correlations between the chemical structure and pharmacological actions of the steroids
27. Progesterone alters GABA and glutamate responsiveness: a possible mechanism for its anxiolytic effect
28. Sex steroid effects on extrahypothalamic CNS. I. Estrogen augments neuronal responsiveness to iontophoretically applied glutamate in the cerebellum
29. Induction of sexual receptivity in ovariectomized rats by pulse administration of oestradiol 17-β
30. Some factors that influence the decrement in the response to GABA during its continuous iontophoretic application to hippocampal neurons
31. Steroid binding to synaptic plasma membrane: differential binding of glucocorticoids and gonadal steroids