A dose-response study of the bronchodilator action of azelastine in asthma

The Journal of Allergy and Clinical Immunology

Volumn 79, Issue 6, 1987, Pages 893-899

  Kemp, James P ^a,b,c,d   Meltzer, Eli O ^a,b,c,d   Orgel, H Alice ^a,b,c,d   Welch, Michael J ^a,b,c,d   Bucholtz, Gerald A ^a,b,c,d   Middleton Jr , Elliott ^a,b,c,d   Spector, Sheldon L ^a,b,c,d   Newton, J J ^a,b,c,d   Perhach Jr , James L ^a,b,c,d  

^a ALLERGY AND ASTHMA MEDICAL GROUP AND RESEARCH CENTER   (United States)

^b Buffalo N Y USA ^*

^c Buffalo   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

AZELASTINE; BRONCHODILATING AGENT; NEW DRUG; NORAZELASTINE; PLACEBO; THEOPHYLLINE; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ADVERSE DRUG REACTION; ASTHMA; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG DOSE; DRUG EFFICACY; DRUG SAFETY; DRUG THERAPY; DRUG TOLERANCE; FORCED EXPIRATORY VOLUME; HUMAN; MAJOR CLINICAL STUDY; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; PRIORITY JOURNAL; RESPIRATORY SYSTEM; SCHOOL CHILD; THERAPY;

ADOLESCENT; ADULT; ASTHMA; BRONCHODILATOR AGENTS; CHILD; CLINICAL TRIALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; HUMANS; KINETICS; LUNG VOLUME MEASUREMENTS; MIDDLE AGED; PHTHALAZINES; PYRIDAZINES; RANDOM ALLOCATION; THEOPHYLLINE;

EID: 0023263198     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/0091-6749(87)90238-7     Document Type: Article

References (17)

1. 1 antagonist properties of azelastine
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3. Inhibition of calcium ionophore (A23187)-stimulated histamine release from rat peritoneal mast cells by azelastine: implications for its mode of action
4. Inhibition of IgE-mediated passive cutaneous anaphylaxis (PCA) by azelastine in rat
5. Inhibition of IgE-mediated allergic histamine release by azelastine from rabbit basophils
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17. Recent advances on the use of antihistamines in the treatment of bronchial obstruction