ROLE OF GENETIC VARIATION AT THE FIBRINOGEN LOCUS IN DETERMINATION OF PLASMA FIBRINOGEN CONCENTRATIONS

The Lancet

Volumn 329, Issue 8548, 1987, Pages 1452-1455

  Humphries, S E ^a   Dubowitz, M ^a   Cook, M ^a   Stirling, Y ^b   Meade, T W ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NORTHWICK PARK HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD AND HEMOPOIETIC SYSTEM; FIBRINOGEN BLOOD LEVEL; GENE LOCUS; GENETIC ENGINEERING; GENETIC VARIABILITY; HEREDITY; HUMAN; HUMAN CELL; ISCHEMIC HEART DISEASE; NORMAL HUMAN; NORMAL VALUE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

FEMALE; FIBRINOGEN; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; VARIATION (GENETICS);

EID: 0023255622     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(87)92205-7     Document Type: Article

References (22)

1. Haemostatic function and cardiovascular death: Early results of a prospective study
2. Hypercoagulability and coronary artery disease
3. Haemostatic function and ischaemic heart disease: Principal results of the Northwick Park Heart Study
4. Fibrinogen as a risk factor for stroke and myocardial infarction
5. Population based distributions of haemostatic variables
6. Characteristics affecting fibrinolytic activity and plasma fibrinogen concentrations
7. Intracellular assembly of human fibrinogen
8. Intracellular assembly of human fibrinogen
9. A partial mRNA sequence for human α, β and γ fibrinogen chains: Evolutionary and functional implications
10. Evolution and organization of the fibrinogen locus on chromosome 4: Gene duplication accompanied by transposition and inversion
11. The identification of a DNA polymorphism of the α-fibrinogen gene, and the regional assignment of the human fibrinogen genes to 4q26-qter
12. Linkage disequilibrium of RFLP's at the beta fibrinogen (FGB) and gamma fibrinogen (FGG) loci on chromosome 4
13. Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants
14. Isolation and characterisation of cDNA clones for the Aα- and γ-chains of human fibrinogen
15. Addendum "A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity"
16. A study of DNA polymorphisms around the human apolipoprotein AI gene in hyperlipidaemic and normal individuals
17. Nonuniform recombination within the human β-globin gene cluster
18. Role of apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation
19. A point mutation in the Ag-globin gene promoter in Greek hereditary persistance of fetal haemoglobin
20. Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes