Low molecular weight heparin fractions as an alternative therapy in heparin-induced thrombocytopenia

Pathophysiology of Haemostasis and Thrombosis

Volumn 17, Issue 3, 1987, Pages 134-140

  Gouault Heilmann, M ^a   Huet, Y ^a   Adnot, S ^a   Contant, G ^a   Bonnet, F ^a   Intrator, L ^a   Payen, D ^a   Levent, M ^a  

^a UNIVERSITÉ PARIS EST CRÉTEIL   (France)

Author keywords

Heparin induced thrombocytopenia; Low molecular weight heparin fractions

Indexed keywords

ENOXAPARIN; ENOXIPARINE; HEPARIN; HEPARIN FRACTION; LOW MOLECULAR WEIGHT HEPARIN; NADROPARIN; NEW DRUG; UNCLASSIFIED DRUG;

BLOOD AND HEMOPOIETIC SYSTEM; CLINICAL ARTICLE; DRUG COMPARISON; DRUG EFFICACY; DRUG THERAPY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; THERAPY; THROMBOCYTE AGGREGATION;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; HEPARIN; HUMANS; MALE; MIDDLE AGED; PLATELET AGGREGATION; PLATELET COUNT; PROSPECTIVE STUDIES; THROMBOCYTOPENIA;

EID: 0023239215     PISSN: 14248832     EISSN: 14248840     Source Type: Journal    
DOI: 10.1159/000215571     Document Type: Article

References (28)

1. Godal, H.C.: Report of the International Committee on Thrombosis and Haemostasis: thrombocytopenia and heparin. Thromb. Haemostasis 43: 222-224 (1980).
2. Malcolm, I.D., Wigmore, T.A., Steinbrecher, U.P.: Heparin-associated thrombocytopenia: low frequency in 104 patients treated with heparin of intestinal mucosal origin. Can. med. Ass. J. 120: 1086-1088 (1979).
3. Bell, W.R., Tomasulo, P.A., Alving, B.M., Duffy, T.P.: Thrombocytopenia occurring during the administration of heparin: a prospective study in 52 patients. Ann. intern. Med. 85: 155-160 (1976).
4. Bell, W.R., Royall, R.M.: Heparin associated thrombocytopenia: a comparison of three heparin preparations. New Engl. J. Med. 303: 902-907 (1980).
5. Babcock, R.B., Dumper, C.W., Scharfman, W.B.: Heparin-induced thrombocytopenia. New Engl. J. Med. 295: 237-241 (1976).
6. Greene, D., Harris, K., Reynolds, N., Roberts, M., Patterson, R.: Heparin immune thrombocytopenia: evidence for an heparin-platelet complex as the antigenic determinant. J. Lab. clin. Med. 91: 167-175 (1978).
7. King, D.J., Kelton, J.G.: Heparin associated thrombocytopenia. Ann. intern. Med. 100: 535-540 (1984).
8. Rhodes, G.R., Dixon, R.H., Silver, D.: Heparin-induced thrombocytopenia: eight cases with thrombotic-hemorrhagic complications. Ann. Surg. 186: 752-758 (1977).
9. Huisse, M.G., Guillin, M.C., Bezeaud, A., Toule-monde, F., Kitzis, M., Andreassian, B.: Heparin associated thrombocytopenia. In vitro effects of different molecular weight heparin fractions. Thromb. Res. 27: 485-490 (1982).
10. Huisse, M.G., Huet, Y., Zygelman, M., Guillin, M.C.: Thrombopénie induite par l’héparine. Tentative thérapeutique à l’aide d’une héparine de bas poids moléculaire (Letter). Presse méd. 12: 643 (1983).
11. Pourrat, E., Laurent, G., Sie, P., Lacheheb, M., Bemies, M., Desrez, X.: Substitution d’une héparine de bas poids moléculaire à l’héparine standard en cas de thrombopénie allergique (Letter). Presse méd. 12: 1875 (1983).
12. Gouault-Heilmann, M., Contant, G., Pochmalic-ki, G., Jan, F.: Coagulation intravasculaire disséminée induite par l’héparine. Traitement par l’association héparine de bas poids moléculaire et concentrés d’antithrombine III (Letter). Presse méd. 13: 1313 (1984).
13. Roussi, J.H., Houbouyan, L.L., Goguel, A.F.: Use of low molecular weight heparin in heparin-in-duced thrombocytopenia with thrombotic complications (Letter). Lancet ii: 1183 (1984).
14. Condouret, J., Lassoued, S., Roques, C.F., Bier-me, R., Bismuth, M., Pujol, M.: Association thrombose-thrombopénie induites par l’héparine. Traitement par une héparine de bas poids moléculaire (Letter). Presse méd. 13: 2455 (1984).
15. Horellou, M.H., Conard, J., Lecrubier, C., Sama-ma, M., Roque-D’Orbcastel, O., Fenoyl, O. de; Di Maria, G., Bemadou, A.: Persistent heparin-in-duced thrombocytopenia despite therapy with low molecular weight heparin (Letter). Thromb. Haemostasis 51: 134 (1984).
16. Gouault-Heilmann, M., Huet, Y., Contant, G., Payen, D., Bloch, G., Rapin, M.: Cardiopulmonary bypass with a low molecular weight heparin fraction (Letter). Lancet ii: 1374 (1983).
17. Teien, A., Lie, M.: Evaluation of an amydolytic heparin assay method: increased sensitivity by adding purified antithrombin III. Thromb. Res. 10: 399-410 (1977).
18. Carreras, L.O.: Thrombosis and thrombocytopenia induced by heparin; in Verstraete, Machin, Clinical usage of heparin. Present and future trends. Scand. J. Haematol. 25: suppl. 36, pp. 64-80 (1980).
19. Gollub, S., Ulin, A.W.: Heparin-induced thrombocytopenia in man. J. Lab. clin. Med. 59: 430-435 (1962).
20. Cines, D.B., Kaywin, P., Bina, M., Tomaski, A., Schreiber, A.D.: Heparin associated thrombocytopenia. New Engl. J. Med. 303: 788-795 (1980).
21. Rhodes, G.R., Dixon, R.H., Silver, D.: Heparin induced thrombocytopenia with thrombotic and hemorrhagic manifestations. Surgery Gynec. Obstet. 136: 409-416 (1973).
22. Trowbridge, A.A., Caraveo, J., Green, J.B., III; Amaral, B., Stone, M.J.: Heparin-related immune thrombocytopenia. Studies of antibody-heparin specificity. Am. J. Med. 65: 277-283 (1978).
23. Olin, J., Graor, R.: Heparin associated thrombocytopenia (Letter). New Engl. J. Med. 304: 609 (1981).
24. Nelson, J.C., Lemer, R.G., Golstein, R., Cagin, N.A.: Heparin-induced thrombocytopenia. Archs intern. Med. 138: 548-552 (1978).
25. Eldor, A., Weksler, B.B.: Heparin and dextran sulfate antagonize PGI2 inhibition of platelet aggregation. Thromb. Res. 16: 617-628 (1979).
26. McDuffie, N.M., Dietrich, C.P., Nader, H.B.: Electrofocusing of heparin: fractionation of heparin into 21 components distinguishable from other acidic mucopolysaccharides. Biopolymers 14: 1473-1486 (1975).
27. Dunn, F.W., Soria, C., Thomaidis, A., Soria, J., Dupuy, E., Bellucci, S., Tobelem, G.: Interactions of platelets with standard heparin and low molecular weight fractions. Nouv. Revue fr. Hémat. 26: 249-253 (1984).
28. Messmore, H.L., Fareed, J., Parvey, Z., Squillac, G.: Heparin induced thrombocytopenia. Can low molecular weight heparins be substituted safely? (Abstract). Thromb. Haemostasis 50: 55 (1983).