Acyclic stereochemical control using hexacarbonyldicobalt stabilized propargyl cation. A highly stereoselective route to 1β-methylcarbapenem precursors.

Tetrahedron Letters

Volumn 28, Issue 17, 1987, Pages 1857-1860

  Rrasad, J Siva ^a   Liebeskind, Lanny S ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1BETA METHYLCARBAPENEM DERIVATIVE; 2 AZETIDINONE DERIVATIVE; UNCLASSIFIED DRUG;

DRUG SYNTHESIS; METHODOLOGY; NONHUMAN; PRELIMINARY COMMUNICATION; THEORETICAL STUDY;

EID: 0023235394     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)95993-8     Document Type: Article

References (26)

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3. Synthetic Carbapenem Antibiotics. I. 1-b-Methylcarbapenem
4. Highly diastereoselective alkylation onto 4-acetoxy-2-azetidinones employing tin(II) enolates of 3-acyl C-4-chiral 1,3-thiazolidine-2-thiones
5. A facile, stereocontrolled entry to key intermediates for thienamycin synthesis from ethyl (S)-3-hydroxybutanoate.
6. Synthetic Carbapenem Antibiotics. I. 1-b-Methylcarbapenem
7. Torsional strain involving partial bonds. The stereochemistry of the lithium aluminium hydride reduction of some simple open-chain ketones
8. Regio- and stereo-selectivities in some nucleophilic reactions
9. Cleavage of the carbon-silicon bond in 1-alkynylsilanes by silver nitrate: Protection of a terminal triple bond in hydrogenation reactions with the trimethylsilyl group
10. Deoxygenation of Acetylenic Carbinols. Reduction of Cobalt Carbonyl Adducts with Borane-Methyl Sulfide and Trifluoroacetic Acid
11. Cobalt-mediated cyclopentenone annelation: an approach to the synthesis of cyclocolorenone