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Volumn 28, Issue 1, 1987, Pages 43-47

Inhibition of rat testicular 17α-hydroxylase and 17,20-lyase activities by anti-androgens (flutamide, hydroxyflutamide, ru23908, cyproterone acetate) in vitro

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE-LYASES; ANDROGEN ANTAGONISTS; ANIMAL; CYPROTERONE; CYPROTERONE ACETATE; CYTOCHROME P-450 ENZYME SYSTEM; FLUTAMIDE; IMIDAZOLES; KINETICS; MALE; MICROSOMES; RATS; RATS, INBRED STRAINS; STEROID 17-ALPHA-HYDROXYLASE; STEROID HYDROXYLASES; TESTIS;

EID: 0023228346     PISSN: 00224731     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-4731(87)90122-1     Document Type: Article
Times cited : (63)

References (24)
  • 2
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    • Clinical experience with cyproterone acetate for palliation of inoperable prostate cancer
    • 4th edn., G.H. Jacobi, R. Hohenfellner, Williams and Wilkins, Baltimore
    • (1982) Prostate Cancer , vol.3 , pp. 305-319
    • Jacobi1    Tunn2    Senge3
  • 8
    • 0018758385 scopus 로고
    • Effects of cyproterone and cyproterone acetate on the adrenal gland of the rat: Studies in vivo and in vitro
    • (1979) J. Endocr. , vol.80 , pp. 229-238
    • Panesar1    Merries2    Stitch3
  • 10
    • 0021163548 scopus 로고
    • Inhibition of basal and adrenocorticotropin-stimulated plasma levels of adrenal androgens after treatment with an antiandrogen in castrated patients with prostatic cancer
    • (1984) J. clin. Endocr. Metab. , vol.59 , pp. 422-426
    • Belanger1    Dupont2    Labrie3
  • 13
    • 0015894520 scopus 로고
    • The effect of cyproterone acetate on androgen biosynthesis by the rabbit testis
    • (1971) J. Endocr. , vol.57 , pp. iv
    • Grants1    Stitch2
  • 16
    • 0019874673 scopus 로고
    • Microsomal cytochrome P-450 from neonatal pig testis: Two enzymatic activities (17α-hydroxylase and C-17,20-lyase) associated with one protein
    • (1981) Biochemistry , vol.20 , pp. 4037-4042
    • Nakajin1    Shirely2    Yuan3    Hall4
  • 17
    • 0019521110 scopus 로고
    • Inhibition of testicular microsomal cytochrome P-450 17α-hydroxylase/ C-17,20-lyase by oestrogens
    • (1981) Endocrinology , vol.109 , pp. 763-767
    • Onada1    Hall2
  • 23


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.