Effect of Recombinant Human Granulocyte–Macrophage Colony-Stimulating Factor on Myelopoiesis in the Acquired Immunodeficiency Syndrome

New England Journal of Medicine

Volumn 317, Issue 10, 1987, Pages 593-598

  Groopman, Jerome E ^a,b,c   Mitsuyasu, Ronald T ^d   Deleo, Michael J ^e   Oette, Dagmar H ^e   Golde, David W ^e  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b Sandoz Pharma Ltd   (Switzerland)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Genetics Institute Inc ^*  (United States)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; BLOOD AND HEMOPOIETIC SYSTEM; CLINICAL ARTICLE; DRUG THERAPY; EOSINOPHIL; HUMAN; INFECTION RESISTANCE; LEUKOCYTE; MONOCYTE; NEUTROPENIA; NEUTROPHIL; PRIORITY JOURNAL; THERAPY;

EID: 0023227509     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM198709033171003     Document Type: Article

References (32)

1. Metcalf D. The granulocytemacrophage colony-stimulating factors. Science 1985; 229: 16–22.
2. Clark SC, Kamen R. The human hematopoietic colony-stimulating factors. Science 1987; 236: 1229–37.
3. Golde DW, Takaku F, eds. Hematopoietic stem cells. New York: Marcel Dekker, 1985.
4. Wong GG, Witek JS, Temple PA, et al. Human GM-CSF: molecular cloning of the complementary DNA and purification of the natural and recombinant proteins. Science 1985; 228: 810–5.
5. Gasson JC, Weisbart RH, Kaufman SE, et al. Purified human granulocytemacrophage colony-stimulating factor: direct action on neutrophils. Science 1984; 226: 1339–42.
6. Metcalf D, Begley CG, Johnson GR, et al. Biologic properties in vitro of a recombinant human granulocytemacrophage colony-stimulating factor. Blood 1986; 67: 37–45.
7. Tomonaga M, Golde DW, Gasson JC. Biosynthetic (recombinant) human granulocytemacrophage colony-stimulating factor: effect on normal bone marrow and leukemia cell lines. Blood 1986; 67: 31–6.
8. Grabstein KH, Urdal DL, Tushinski RJ, et al. Induction of macrophage tumoricidal activity by granulocytemacrophage colony-stimulating factor. Science 1986; 232: 506–8.
9. Weisbart RH, Golde DW, Clark SC, Wong GG, Gasson JC. Human granulocytemacrophage colony-stimulating factor is a neutrophil activator. Nature 1985; 314: 361–3.
10. Weisbart RH, Golde DW, Gasson JC. Biosynthetic human GM-CSF modulates the number and affinity of neutrophil f-met-Leu-Phe receptors. J Immunol 1986; 137: 3584–7.
11. Fleischmann J, Golde DW, Weisbart RH, Gasson JC. Granulocytemacrophage colony-stimulating factor enhances phagocytosis of bacteria by human neutrophils. Blood 1986; 68: 708–11.
12. Hammer SM, Gillis JM, Groopman JE, Rose RM. In vitro modification of human immunodeficiency virus infection by granulocytemacrophage colony-stimulating factor and gamma interferon. Proc Natl Acad Sci USA 1986; 83: 8734–8.
13. Donahue RE, Wang EA, Stone DK, et al. Stimulation of haematopoiesis in primates by continuous infusion recombinant human GM-CSF. Nature 1986; 321: 872–5.
14. Gottlieb MS, Schroff R, Schanker HM, et al. Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: evidence of a new acquired cellular immunodeficiency. N Engl J Med 1981; 305: 1425–31.
15. Masur H, Michelis MA, Greene JB, et al. An outbreak of community-acquired Pneumocystis carinii pneumonia: initial manifestation of cellular immune dysfunction. N Engl J Med 1981; 305: 1431–8.
16. Siegal FP, Lopez C, Hammer GS> et al. Severe acquired immunodeficiency in male homosexuals, manifested by chronic perianal ulcerative herpes simplex lesions. N Engl J Med 1981; 305: 1439–44.
17. Armstrong D, Gold JWM, Dryjanski J, et al. Treatment of infections in patients with the acquired immunodeficiency syndrome. Ann Intern Med 1985; 103: 738–43.
18. Bowen DL, Lane HC, Fauci AS. Immunopathogenesis of the acquired immunodeficiency syndrome. Ann Intern Med 1985; 103: 704–9.
19. Murray HW, Rubin BY, Masur H, Roberts RB. Impaired production of Iymphokines and immune (gamma) interferon in the acquired immunodeficiency syndrome. N Engl J Med 1984; 310: 883–9.
20. Smith PD, Ohura K, Masur H, Lane HC, Fauci AS, Wahl SM. Monocyte function in the acquired immune deficiency syndrome: defective chemotaxis. J Clin Invest 1984; 74: 2121–8.
21. Zon LI, Arkin C, Groopman JE. Haematologic manifestations of human immunodeficiency virus (HIV) infection. Br J Haematol 1987; 66: 251–6.
22. Spivak JL, Selonick SE, Quinn TC. Acquired immune deficiency syndrome and pancytopenia. JAMA 1983; 250: 3084–7.
23. Castella A, Croxson TS, Mildvan D, Witt DH, Zalusky R. The bone marrow in AIDS: a histologic, hematologic, and microbiologic study. Am J Clin Pathol 1985; 84: 425–32.
24. Yarchoan R, Broder S. Development of antiretroviral therapy for the acquired immunodeficiency syndrome and related disorders: a progress report. N Engl J Med 1987; 316: 557–64.
25. Groopman JE, Salahuddin SZ, Sarngadharan MG, et al. Virologic studies in a case of transfusion-associated AIDS. N Engl J Med 1984; 311: 1419–22.
26. Griffin JD, Sullivan R, Beveridge RP. Larcom P, Schlossman SF. Induction of proliferation of purified human myeloid progenitor cells: a rapid assay for granulocyte colony-stimulating factors. Blood 1984; 63: 904–11.
27. Hocking W, Goodman J, Golde D. Granulocytosis associated with tumor cell production of colony-stimulating activity. Blood 1983; 61: 600–3.
28. Ikeda K, Motoyoshi K, Ishizaka Y, et al. Human colony-stimulating activity-producing tumor: production of very low mouse-active colony-stimulating activity and induction of marked granulocytosis in mice. Cancer Res 1985; 45: 4144–9.
29. Pachman LM, Schwartz AD, Barron R, Golde DW. Chronic neutropenia: response to plasma with high colony-stimulating activity. J Pediatr 1975; 87: 713–9.
30. Motoyoshi K, Takaku F, Maekawa T, et al. Protective effect of partially purified human urinary colony-stimulating factor on granulocytopenia after antitumor chemotherapy. Exp Hematol 1986; 14: 1069–75.
31. Motoyoshi K, Takaku F, Miura Y. High serum colony-stimulating activity of leukocytopenic patients after intravenous infusions of human urinary colony-stimulating factor. Blood 1983; 62: 685–8.
32. Donahue RE, Johnson MM, Zon LI, Clark SC, Groopman JE. Suppression of in vitro haematopoiesis following human immunodeficiency virus infection. Nature 1987; 326: 200–3.