Randomized phase III trial of single versus multiple chemotherapeutic treatment following surgery and during radiotherapy for patients with anaplastic gliomas

Surgical Neurology

Volumn 27, Issue 5, 1987, Pages 430-432

  Mahaley Jr , M S ^a   Whaley, Robert A ^a   Krigman, Martin R ^a   Bouldin, Thomas W ^a   Bertsch, Linda ^a   Cush, Sharon ^a  

^a 3010 Old Clinic Bldg   (United States)

Author keywords

Anaplastic gliomas; Multiple agent chemotherapy

Indexed keywords

ANTIMITOTIC AGENT; CARMUSTINE; HYDROXYUREA; PROCARBAZINE; TENIPOSIDE;

CHEMOTHERAPY; DRUG COMPARISON; DRUG DOSE; DRUG EFFICACY; DRUG MECHANISM; DRUG MIXTURE; GLIOMA; HUMAN; MAJOR CLINICAL STUDY; NERVOUS SYSTEM; NEUROSURGERY; PRIORITY JOURNAL; RADIOTHERAPY; THERAPY;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BRAIN NEOPLASMS; CARMUSTINE; CLINICAL TRIALS; COMBINED MODALITY THERAPY; GLIOMA; HUMANS; HYDROXYUREA; METHYLPREDNISOLONE; MIDDLE AGED; MITOLACTOL; PROCARBAZINE; RANDOM ALLOCATION; TENIPOSIDE; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0023226973     PISSN: 00903019     EISSN: None     Source Type: Journal    
DOI: 10.1016/0090-3019(87)90248-5     Document Type: Article

References (13)

1. Combined radiotherapy and chemotherapy with dibromodulcitol and CCNU in the postoperative treatment of malignant gliomas
2. Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas
3. Randomized comparisons of radiotherapy and CCNU versus radiotherapy, CCNU plus procarbazine for the treatment of malignant gliomas following surgery
4. A pilot study of cis-diamminedichloroplatinum and radiation therapy in patients with high grade astrocytomas
5. Comparisons of carmustine, procarbazine, and high-dose methylprednisolone as additions to surgery and radiotherapy for the treatment of malignant glioma
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9. Limitations of high dose intra-arterial 1,3-bis(2-chloroethyl)-1-nitrosourea(BCNU)chemotherapy for malignant gliomas
10. New implantable continuous administration and bolus dose intracarotid drug delivery system for the treatment of malignant gliomas
11. Superfractionation radiation therapy in the treatment of malignant astrocytoma
12. Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery
13. Intraarterial 1,3-bis(2-chlorotheyl)-l-nitrosourea (BCNU) and systemic chemotherapy for malignant gliomas: a follow-up study