Changes in thyroid hormones and thyroxine glucuronidation in hamsters compared with rats following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin

Toxicology and Applied Pharmacology

Volumn 89, Issue 2, 1987, Pages 165-174

  Henry, Ellen C ^a   Gasiewicz, Thomas A ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; GLUCURONOSYLTRANSFERASE;

ANIMAL EXPERIMENT; ENZYME INDUCTION; GLUCURONIDATION; HAMSTER; INTOXICATION; LIOTHYRONINE BLOOD LEVEL; NONHUMAN; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE; THYROXINE BLOOD LEVEL;

ANIMAL; COMPARATIVE STUDY; DIOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCURONATES; GLUCURONOSYLTRANSFERASE; HAMSTERS; MALE; MESOCRICETUS; RATS; RATS, INBRED STRAINS; SUPPORT, U.S. GOV'T, P.H.S.; TETRACHLORODIBENZODIOXIN; THYROID HORMONES; THYROTROPIN; THYROXINE; TIME FACTORS; TRIIODOTHYRONINE; TRIIODOTHYRONINE, REVERSE;

EID: 0023217774     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/0041-008X(87)90037-8     Document Type: Article

References (38)

1. Organ specific induction of drug metabolizing enzymes by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat
2. The biliary excretion of thyroxine and its glucuronic acid conjugate in normal and Gunn rats
3. Enhanced thyroxine metabolism and high uptake goiters in rats after a single dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin
4. Goiters in rats fed polychlorinated biphenyls
5. Enhanced in vitro hepatic glucuronidation of thyroxine in rats following cutaneous application or ingestion of polychlorinated biphenyls
6. Recovery from energy deficit in golden hamsters
7. Effects of an acute bacterial infection on serum thyroid hormones and nuclear triiodothyronine receptors in mice
8. Misleadingly low free thyroxine index and usefulness of reverse triiodothyronine measurement in nonthyroidal illnesses
9. Serum T4 and T3 in active and torpid ground squirrels, Spermophilus richardsoni
10. Cytosolic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: Evidence for a homologous nature among various mammalian species
11. Changes in hamster hepatic cytochrome P-450, ethoxycoumarin O-deethylase, and reduced NAD(P): menadione oxidoreductase following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin
12. Effect of thyroidectomy on the Ah receptor and enzyme inducibility by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat liver
13. Nonshivering thermogenesis
14. Induction and suppression of hepatic and extrahepatic microsomal foreign-compound-metabolizing enzyme systems by 2,3,7,8-tetrachlorodibenzo-p-dioxin
15. Peripheral serum thyroxine, triiodothyronine and reverse triiodothyronine kinetics in low thyroxine state of nonthyroidal illnesses
16. Decreased serum triiodothyronine in starving rats is due primarily to diminished thyroidal secretion of thyroxine
17. 2378-Tetrachlorodibenzo-p-dioxin (TCDD) effects on hepatic microsomal cytochrome P-448-mediated enzyme activities
18. Effects of thyroid hormones on the induction of cleft palate by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in C57BL/6N mice
19. Comparison of in vitro drug metabolism by lung, liver and kidney of several laboratory species
20. Effect of thyroid hormone supplementation on survival after bacterial infection
21. Nature of the enhancement of uridine diphosphate glucuronyltransferase activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats
22. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) as a potent and persistent thyroxine agonist: A mechanistic model for toxicity based on molecular reactivity
23. Tissue distribution, excretion, and metabolism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the Golden Syrian hamster
24. Effect of thyroidectomy and thyroxine on 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunotoxicity
25. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: Examination of the mechanism of toxicity
26. Thyroid status and thermogenesis in rats treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin
27. Hypothyroxinemia and hypothermia in rats in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin administration
28. Influence of pinealectomy on the breeding capability of hamsters maintained under natural photoperiodic and temperature conditions
29. Effect of thyroid hormones on liver microsomal enzyme induction in rats exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin
30. Histopathology of interscapular brown adipose tissue, thyroid, and pancreas in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated rats
31. Effect of thyroidectomy and thyroxine on 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced toxicity
32. Thyroid hormones modulate the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
33. The production and metabolism of 3,5,3′-triiodothyronine and 3,3′-5′-triiodothyronine in normal and fasting subjects
34. The effects of cold exposure and hibernation on the thyroidal activity of Mesocricetus auratus
35. Animal models of nonthyroidal disease
36. 3) and cholesterol in female Syrian hamsters
37. Chemically-induced alteration of UDP-glucuronic acid concentration in rat liver