The major histocompatibility complex of the rat

Transplantation

Volumn 43, Issue 6, 1987, Pages 773-785

  Gill, Thomas J ^a   Kunz, Heinz W ^a   Misra, Dhirendra N ^a   Cortese Hassett, Andrea L ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD GROUP ANTIGEN;

BLOOD AND HEMOPOIETIC SYSTEM; HEREDITY; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW;

AMINO ACID SEQUENCE; ANIMAL; HAPLOIDY; MAJOR HISTOCOMPATIBILITY COMPLEX; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RATS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TERMINOLOGY;

EID: 0023217662     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-198743060-00001     Document Type: Article

References (198)

1. Frenzl B, Kren V, Stark O. Attempt to determine blood groups in rats. Folia Biol (Prague) 1960; 6: 121.
2. Brdicka R, Kren V, Frenzl B, Stark O. Interlineal relationships in rats. Folia Biol (Prague) 1962; 8: 352.
3. Bogden AE, Aptekman PM. Histocompatibility antigens and hemagglutinogens in the rat. Ann NY Acad Sci 1962; 97: 43.
4. Bogden AE, Aptekman PM. Immunogenetic studies of a histocompatibility hemagglutinogen (R-l) in the rat. J Natl Cancer Inst 1961; 26: 641.
5. Owen RD. Earlier studies of blood groups in rats. Ann NY Acad Sci 1962; 97: 37.
6. Palm J. Current status of blood groups in rats. Ann NY Acad Sci 1962; 97: 57.
7. Heslop BF. Histocompatibility antigens in the rat: the AS2 strain in relation to the AS, BS and HS strains. Aust J Exp Biol Med Sci 1968; 46: 479.
8. Stark O, Kren V, Frenzl B. Erythrocyte and transplantation antigens in inbred strains of rats: I. Serological analysis of strain-specific antigens. Folia Biol (Prague) 1967; 13: 85.
9. Stark O, Kren V. Erythrocyte and transplantation antigens in inbred strains of rats: VI. The histocompatibility-1 system and its alleles. Folia Biol (Prague) 1967; 13: 356.
10. Stark O, Krenova D, Kren V, Frenzl B. Immunological relationships between five congenie lines of rats and their parental strains. Folia Biol 1970; 16: 1.
11. Palm J. Classification of inbred rat strains for Ag-B histocompatibility antigens. Transplant Proc 1971; 3: 169.
12. Palm J. Immunogenetic analysis of Ag-B histocompatibility antigens in rats. Transplantation 1971; 11: 175.
13. Palm J, Black G. Interrelationships of inbred rat strains with respect to Ag-B and non Ag-B antigens. Transplantation 1971; 11: 184.
14. Hausman SJ, Palm J. Variable expression of Ag-B and non Ag-B histocompatibility antigens on cultured rat cells of different histological origin. Transplantation 1973; 16: 313.
15. Palm J, Rigiero C, Black G. Further studies on the number of histocompatibility loci in rats. Immunogenetics 1977; 4: 79.
16. Natori T, Kanada M, Ohhashi T, Iwabuchi Komuro K, Aizawa M. An estimate of the gene sequence in the major histocompatibility complex of the rat: RT1. Transplant Proc 1979; 11:1568.
17. Ohhashi T, Iwabuchi K, Natori T, Kakagawa H, Kikuchi Y, Aizawa M. The B-region associated antigens and MLR pheno-types in the Japanese inbred strains of rats. J Immunogenet 1981; 8: 191.
18. Stark O, Günther E, Kunz HW, Gill TJ III. Comparison of haplotypes of the major histocompatibility complex in the rat: I. The Ag-B7 (H-lg) and Ag-B8 (H-lk) haplotypes. J Immunogenet 1977; 4: 405.
19. Kunz HW, Stark O, Gill TJ III. Comparison of haplotypes of the major histocompatibility complex in the rat: II. Serological analysis of the haplotypes H-l8 (Ag-B4), H-ld (Ag-B9) and H-1’ (Ag-B10). J Immunogenet 1977; 4: 411.
20. Stark O, Kunz HW, Gill TJ III. Comparison of haplotypes of the major histocompatibility complex in the rat: III. Two difficult haplotypes: H-lh (Ag-B12) in the HW strain and Ag-B13 (H-1") in the MNR/N strain. J Immunogenet 1978; 6: 115
21. Stark O, Kunz HW, Gill TJ III. Comparison of the haplotypes of the major histocompatibility complex in the rat: IV. The six original Ag-B haplotypes. J Immunogenet 1978; 5: 261.
22. Arenas O, Wagener DK, Kunz HW, Gill TJ III. Comparison of the haplotypes of the major histocompatibility complex in the rat: V. A serological, genetic and numerical study of the RT1.A region antigens. J Immunogenet 1981; 8: 307.
23. Kunz HW, Gill TJ III. Red blood cell alloantigenic systems in the rat. J Immunogenet 1978; 5: 365.
24. International Workshops on Alloantigenic Systems in the Rat. I. Transplant Proc 1978; 10:271; II. ibid 1979; 11:1549; III. ibid 1981; 13:1307; IV. ibid 1983; 15:1533; V. 1985; 17:1793; VI. ibid (in press).
25. Günther E, Stark O. The major histocompatibility system of the rat (Ag-B or H-l system). In: Goetz D, ed. The histocompatibility system in man and animals. New York: Springer-Verlag, 1977: 206.
26. Gill TJ III, Cramer DV, Kunz HW. The major histocompatibility complex: comparison in the mouse, man and the rat. Am J Pathol 1978; 90: 735.
27. Gill TJ III, Cramer DV, Kunz HW, Misra DN. Structure and function of the major histocompatibility complex of the rat. J Immunogenet 1983; 10: 261.
28. Gill TJ III. The rat in biomedical research. Physiologist 1985; 28: 9.
29. Butcher GW, Howard JC. Genetic control of transplant rejection. Transplantation 1982; 34: 161.
30. Howard JC. The major histocompatibility complex of the rat: a partial review. Metabolism 1983; 32: 41.
31. Aizawa M, Natori T. Transplantation immunobiology in the rat. In: Yamamura Y, Tada T, eds. Progress in Immunology, Vol V. New York: Academic Press, 1983: 1439.
32. Calhoun JB. The ecology and sociology of the Norway rat. Bethesda, Maryland: US Department of Health, Education and Welfare, 1962 (PHS Publication No. 1008).
33. Robinson R. Genetics of the Norway rat. Oxford: Pergamon, 1965.
34. Festing MFW. Inbred strains in biomedical research. New York: Oxford University, 1979.
35. Altman PL, Katz DD (eds). Inbred and genetically defined strains of laboratory animals. I. Mouse and rat. Bethesda, Maryland: Federation of American Societies for Experimental Biology, 1979.
36. Kunz HW, Gill TJ III. Genetic studies in inbred rats: I. Two new histocompatibility alleles. J Immunogenet 1974; 1: 413.
37. Cramer DV, Shonnard JW, Gill TJ III. Genetic studies in inbred rats: II. Relationship between the major histocompatibility complex and mixed lymphocyte reactivity. J Immunogenet 1974; 1: 421.
38. Kunz HW, Gill TJ III, Dixon B, Shonnard JW, Davis BK, Hansen CT. Genetic and immunological characterization of naturally occurring recombinant B3 rats. Immunogenetics 1977; 5: 271.
39. Butcher GW, Howard JC. A recombinant in the major histocompatibility complex of the rat. Nature 1977; 266: 326.
40. Stark O, Günther E, Kohoutová M, Vojcik L. Genetic recombination in the major histocompatibility complex (H-l, Ag-B) of the rat. Immunogenetics 1977; 5: 183.
41. Kohoutava M, Günther E, Stark O. Genetic definition of a further gene region and identification of at least three different histocompatibility genes in the rat major histocompatibility system. Immunogenetics 1980; 11: 483.
42. Gill TJ III, Kunz HW, Schaid DJ, VandeBerg JL, Stole V. Orientation of loci in the major histocompatibility complex of the rat and its comparison to man and the mouse. J Immunogenet 1982; 9: 281.
43. Kunz HW, Gill TJ III, Liebert M, Katz S. Gene order in the major histocompatibility complex in the rat. Immunogenetics 1981; 13: 371.
44. Kohoutová M, Günther E, Stark O. Further two recombinants at the major histocompatibility complex of the rat. Folia Biol (Praha) 1978; 24: 406.
45. Lynch DH, DeWitt CW. Genetic identification of a locus linked to the rat MHC that codes for a membrane antigen detectable with cytotoxic lymphocytes. J Immunol 1978; 121: 2367.
46. Kohoutová M, Vojcik L, Günther E, Stark O. Analysis of a new RT1 recombinant haplotype. Transplant Proc 1979; 11: 1588.
47. Butcher GW, Howard JC. Second International Workshop on Alloantigenic Systems in the Rat. Rat News Letter 1979; 5: 12.
48. Kunz HW, Gill TJ III, Dixon BD, Taylor FH, Greiner DL. Growth and reproduction complex in the rat: genes linked to the major histocompatibility complex that affect development. J Exp Med 1980; 152: 1506.
49. Lobel SA, Cramer DV. Demonstration of a new genetic locus in the major histocompatibility system of the rat. Immunogenetics 1981; 13: 465.
50. Wonigeit K, Hanisch L, Steiniger B, Günther E. Recombinants R14 and R15. Rat News Letter 1985; 15: 16.
51. Inomata T, Kunz HW, Gill TJ III. Immunogenetic analysis of rat strains with recombinations in different regions of the MHC. Immunogenetics 1986; 23: 133.
52. Stephenson SP, Butcher GW. The new recombinant haplotypes rl9 and r20 in RT1, the MHC of the rat. Transplantation 1984; 38: 71.
53. Butcher GW. Haplotypes of the rat MHC, RT1, and recombinants derived from them. Rat News Letter 1985; No. 15: 15.
54. Gill TJ III, Kunz HW. Gene complex controlling growth and fertility linked to the major histocompatibility complex in the rat. Am J Pathol 1979; 6: 185.
55. Gill TJ III, Macpherson TA, Ho HN, Kunz HW, Cortese Hassett A, Stranick KS, Locker J. Immunological and genetic factors affecting implantation and development in the rat and in the human. In: Gill TJ III, Wegmann TG, eds. Immunoregulation and fetal survival. New York: Oxford University, 1987; 137.
56. Rao KN, Shinozuka H, Kunz HW, Gill TJ III. Enhanced susceptibility to a chemical carcinogen in rats carrying MHC-linked genes influencing development (gre). Int J Cancer 1984; 34:113.
57. Lingwood C, Kunz HW, Gill TJ III. Deficiency in the regulation of testicular galactolipid sulfotransferase in rats carrying the growth and reproduction complex (gre). Biochem J 1985; 231: 401.
58. Gunsalus GL, Musto NA, Bardin CW, Kunz HW, Gill TJ III. Rats homozygous for the gre have defective transport of androgen binding protein to the epididymis but normal secretion into the blood. Biol Reprod 1985; 33: 1057.
59. Siew S, Gill TJ III, Kunz HW. Ultrastructural investigation of the testicular defect in rats carrying MHC-linked genes affecting development (gre). Am J Pathol 1986; 123: 318.
60. Geyer SJ, Gill TJ III, Kunz HW. Ovarian defect in rats carrying the growth and reproduction complex. J Immunogenet 1983; 10: 55.
61. Schaid DJ, Kunz HW, Gill TJ III. Genie interaction causing embryonic mortality in the rat: epistasis between the Tal and gre genes. Genetics 1982; 100: 615.
62. Gill TJ V, Gill TJ III, Kunz HW, Musto NA, Bardin CW. Genetic and morphometric studies of the heterogeneity in the testicular defect of the H™ rat. Biol Reprod 1984; 31: 595.
63. Cortese Hassett AL, Stranick KS, Locker J, Kunz HW, Gill TJ III. Molecular analysis of the rat MHC: I. Delineation of the major regions in the MHC and in the gre. J Immunol 1986; 137: 373.
64. Greiner DL, Gill TJ III, Kunz HW, Gay VL. Reproductive endocrine profile of a strain of rats which exhibits aspermatogenesis and reduced growth. Biol Reprod 1980; 23: 564.
65. Drescher CK, Jargiello P, Gill TJ III, Kunz HW. Analysis of the Giemsa-banding patterns of the chromosomes from rats carrying the genes of the growth and reproduction complex (gre). J Immunogenet 1980; 7: 427.
66. Gill TJ III, The borderland of embryogenesis and carcinogenesis: MHC-linked genes affecting development and their possible relationship to the development of cancer. BBA Cancer Rev 1984; 738: 93.
67. Gill TJ III. Immunological and genetic factors influencing development and susceptibility to cancer. Genetica (in press).
68. Kunz HW, Gill TJ III, Misra DN. The identification and mapping of a second class I locus in the major histocompatibility complex of the rat. J Immunol 1982; 128: 402.
69. Misra DN, Noeman SA, Kunz HW, Gill TJ III. Identification of two class I antigens coded by the major histocompatibility complex of the rat by using monoclonal antibodies. J Immunol 1982; 128: 1651.
70. Liebert M, Kunz HW, Gill TJ III, Cramer DV. CML characterization of a product of a second class I locus in the rat MHC. Immunogenetics 1982; 16: 143.
71. Liebert M, Kunz HW, Gill TJ III, Cramer DV. Comparison of antigens in the rat MHC that act as CML determinants. Int Arch Allergy Appi Immunol 1983; 72: 279.
72. Cramer DV, Shonnard JW, Davis BK, Gill TJ III. The in vitro lymphocyte proliferative response to poly (Glu52Lys33Tyr15) in inbred rats. Cell Immunol 1977; 28: 167.
73. Cramer DV, Davis BK, Shonnard JW, Gill TJ III. The graft-versus-host reactivity in Ag-B/MLR disparate strains of rats. Transplantation 1977; 23: 498.
74. Radka SF, Cramer DV, Gill TJ III. Ia antigens in inbred rats and their relationships to the MLR phenotype. J Immunol 1977; 119: 2037.
75. Gill TJ III, Kunz HW, Stechschulte DJ, Austen KF. Genetic and cellular factors in the immune response: I. Genetic control of the antibody response to poly Glu51Lys33Tyr15 in the inbred rat strains ACI and F344. J Immunol 1970; 105: 14.
76. Gill TJ III, Kunz HW. Genetic and cellular factors in the immune response: II. Evidence for the polygenic control of the antibody response from further breeding studies and from pedigree analyses. J Immunol 1970; 106: 980.
77. Kunz HW, Gill TJ III, Borland B. The genetic linkage of the immune response to poly (Glu52Lys33Tyr15) to the major histocompatibility locus in inbred rats. J Immunol 1974; 1: 277.
78. Günther E, Rude E, Stark O. Antibody response in rats to the synthetic polypeptide (T, G)-A—L genetically linked to the major histocompatibility system. Eur J Immunol 1972; 2: 151.
79. Davis BK, Kunz HW, Shonnard JW, Gill TJ III. MHC-linked and non-MHC-linked immune response genes in the rat. Transplant Proc 1981; 13: 1046.
80. Davis BK, Kunz HW, Shonnard JW, Gill TJ III. Immune response to poly (Glu52Lys33Tyr15) in congenie rats. Transplant Proc 1981; 13: 1378.
81. Blankenborn EP, Cramer DV. Orientation of the loci encoding RT1.B polypeptides in the major histocompatibility complex of the rat. Immunogenetics 1985; 21: 135.
82. Shonnard JW, Davis BK, Cramer DV, Radka SF, Gill TJ III. The association of immune responsiveness, mixed lymphocyte response, and Ia antigens in natural populations of Norway rats. J Immunol 1979; 123: 778.
83. Günther E. Close association between particular I region-determined cell surface antigens and Ir gene-controlled immune responsiveness to synthetic polypeptides in wild rats. Eur J Immunol 1979; 9: 391.
84. Jungi TW, Gill TJ III, Kunz HW, Jungi R. Genetic control of cell-mediated immunity in the rat: III. T cells restricted by the RT1.A locus recognize viable Listeria but not isolated bacterial antigens. J Immunogenet 1982; 9: 445.
85. Kunz HW, Cramer DV, Gill TJ III, Coffman KP, Davis BK, Shonnard JW. Studies on the RTld, RTl’ and RTF haplotypes of the major histocompatibility complex in the rat. Transplant Proc 1979; 11: 1557.
86. Natori T, Fujimoto Y, Ikeda H, et al. The RTl.B/D-region product defined by rat monoclonal antibodies. Immunogenetics 1985; 22: 511.
87. Stock W, Günther E. Serologic and cellular characterization of products of a new major histocompatibility gene region, RT1.C, of the rat; possible homology to mouse H-2 Qa. J Immunol 1982; 128: 1923.
88. Haustein D, Stock W, Günther E. Rat major histocompatibility RT1.C antigens of restricted tissue distribution consist of two polypeptide chains with molecular weights of about 42,000 and 12,500. Immunogenetics 1982; 15: 271.
89. Günther E, Wurst W. Cytotoxic T lymphocytes of the rat are predominately restricted by RT1.A and not RTl.C-determined major histocompatibility class I antigens. Immunogenetics 1984; 20: 1.
90. Stephenson SP, Morley RC, Butcher GW. Genetics of the rat CT system: its apparent complexity is a consequence of cross-reactivity between the distinct MHC class I antigens RT1.C and RT1.A. J Immunogenet 1985; 12: 101.
91. Inornate T, Kunz HW, Gill TJ III. The rat Ήα-region alloantigens (RT1.G). Transplant Proc (in press).
92. Stole V, Kunz HW, Gill TJ III. The linkage of glyoxylase-I to the major histocompatibility complex in the rat. J Immunol 1980; 125: 1167.
93. Samollow PB, VandeBerg JL, Ford AL, Kunz HW, Gill TJ III. Genetic analysis of liver neuraminidase isozymes in Rattus norvegicus: independent control of NEU-1 and NEU-2 phenotypes. Genetics, 1986; 114: 247.
94. Natori T, Inomata T, Fujimoto Y, et al. Genetic characteristics of the LEJ strain of rats. Rat News Letter 1984; 13: 32.
95. Natori T, Fujimoto Y, Tsuchimoto S, Matsuno Y, Mizuno K, Aizawa M. Distribution of class I and RT2 antigens among laboratory and commercially available inbred rats in Japan. Rat News Letter 1984; 12: 14.
96. Natori T, Tsuchimoto S, Mizuno K, Matsuno Y, Niiyama T, Aizawa M. A new inbred strain (WIN) with an intra-RTl recombination. Rat News Letter 1986; 16: 4.
97. Natori T, Iwabuchi K, Ohhashi T, Inomata T, Nakagawa H, Aizawa M. Phenotypes for the RTl subregions in Japanese inbred strains of rats. Transplant Proc 1981; 13: 1333.
98. Hedrich HJ, Wonigeit K, Günther E. Description of a new RTl variant and mapping of the variant gene to the RT1.C region. Transplant Proc 1983; 15: 1562.
99. Wonigeit K, Schwinzer R, Inomata T, Kunz HW, Gill TJ III. Reactivity of a monoclonal antibody directed against RT1.E" with recombinants defining the RT.C " region. Transplant Proc (in press).
100. Fischer Lindahl K. Definition of medial histocompatibility antigens. Transplant Proc 1983; 15: 1537.
101. Misra DN, Kunz HW, Gill TJ III. Analysis of class I MHC antigens in the rat by monoclonal antibodies. J Immunol 1985; 134: 2520.
102. Ghani AM, Gill TJ III, Kunz HW, Misra DN. Elicitation of the maternal antibody response to the fetus by a broadly shared MHC class I antigenic determinant. Transplantation 1984; 37: 187.
103. Ghani AM, Kunz HW, Gill TJ III. Pregnancy-induced monoclonal antibody to a unique fetal antigen. Transplantation 1984; 37: 503.
104. Macpherson TA, Ho HN, Kunz HW, Gill TJ III. Localization of the Pa antigen on the placenta of the rat. Transplantation 1986; 41: 392.
105. Ho HN, Macpherson TA, Kunz HW, Gill TJ III. The ontogeny of expression of the Pa and A+ antigens on the rat placenta and on fetal tissues. Am J Reprod Immunol Microbiol 1987; 13: 51.
106. Kunz HW, Gill TJ III. The genetic control of the antibody response to the Pa antigen in the rat. Transplantation 1986; 42: 217.
107. Misra DN, Kunz HW, Gill TJ III. Immunochemical evidence for multiple class I antigens coded by the MHC of the rat (RTl) and their differential expression on red blood cells and lymphocytes. J Immunogenet 1983; 10: 379.
108. Harris HW, Kunz HW, Gill TJ III. Cell surface expression of class I transplantation antigens is controlled in vivo by transacting regulatory elements. Transplant Proc 1987; 19: 222.
109. Misra DN, Kunz HW, Cortese Hassett AL, Gill TJ III. Comparison of rat MHC class I antigens by peptide mapping. Immunogenetics 1987; 25: 35.
110. Diamond AG, Larkins AP, Wright B, Ellis ST, Butcher GW, Howard JC. The alloantigenic organization of RT1.A", a class I major histocompatibility complex molecule of the rat. Eur J Immunol 1984; 14: 405.
111. Vandeberg JL, Bittner GN, Meyer GS, Kunz HW, Gill TJ III. Linkage of neuramidase and a-mannosidase to the major histocompatibility complex in the rat. J Immunogenet 1981; 8: 239.
112. Samollow PB, Ford AL, Kunz HW, Gill TJ III. Mapping the Neu-1 locus to the major histocompatibility complex (RTl) in the rat. Immunogenetics (in press).
113. Figueroa F, Klein D, Tewarson S, Klein J. Evidence for placing the Neu-1 locus within the mouse H-2 complex. J Immunol 1982; 129: 2089.
114. Samollow PB, VandeBerg JL, Ford AL, Douglas TC, David CS. Electrophoretic analysis of liver neuraminidase-1 variation in mice and additional evidence concerning the location of Neu-1. J Immunogenet 1986; 13: 29.
115. Samollow PB, VandeBerg JL, Kunz HW, Gill TJ III. Analysis of neuraminidase isozyme phenotypes in mammalian tissues: an electrophoretic approach. Biochem Biophy Res Commun 1985; 126: 1182.
116. Shreffler DC. MHC-linked complement components. In: Parham P, Strominger J, eds. Histocompatibility antigens: structure and function. London: Chapman and Hall, 1982: 182.
117. Knauer G, Cramer DV, Mowbray JF, Gill TJ III. Detection of an Ss-like protein in the sera of inbred and wild rats. Immunogenetics 1978; 6: 323.
118. Watters JWF, Locker JD, Kunz HW, Gill TJ III. Polymorphism and mapping of the complement gene C4 in the rat. Immunogenetics 1987; 25: 204.
119. Chaplin DD, Woods DE, Whitehead AS, Goldberger G, Colten HR, Seidman JG. Molecular map of the murine S region. Proc Natl Acad Sci USA 1983; 80: 6947.
120. Donner ME, Skow LC, Kunz HW, Gill TJ III. Electrophoretic variation in low molecular weight lens crystallin from inbred strains in rats. Biochem Genet 1985; 23: 787.
121. Skow LC, Kunz HW, Gill TJ III. Linkage of the locus encoding the A chain of a-crystallin (Acry-1) to the major histocompatibility complex in the rat. Immunogenetics 1985; 22: 291.
122. Kunz HW, Cramer DV, Gill TJ III. Comparison of RTl haplotypes using congenie lines. Transplant Proc 1981; 13: 1494.
123. Shonnard JW, Cramer DV, Polosky PE, Kunz HW, Gill TJ III. Polymorphism of the major histocompatibility locus in the wild Norway rats. Immunogenetics 1976; 3: 193.
124. Cramer DV, Davis BK, Shonnard JW, Stark O, Gill TJ III. Phenotypes of the major histocompatibility complex in wild rats of different geographic origins. J Immunol 1978; 120: 179.
125. Klein J, Figueroa F, Klein D. H-2 haplotype, genes and antigens: second listing: I. Non-H-2 loci on chromosome 17. Immunogenetics 1982; 16: 285.
126. Albert ED, Bann MD, Mayr WR, eds. Histocompatibility testing 1984. Berlin: Springer, 1984.
127. Bender K, Adams M, Baverstock PR, et al. Biochemical markers in inbred strains of the rat (Rattus norvegicus). Immunogenetics 1984; 19: 257.
128. Adams M, Baverstock PR, Watts CHS, Gutman GA. Enzyme markers in inbred rat strains: genetics of new markers and strain profiles. Biochem Genet 1984; 22: 611.
129. O’Brien SJ, Gail MH, Levin DL. Correlative genetic variation in natural populations of cats, mice and men. Nature 1980; 288: 580.
130. Harris H, Hopkinson DA, Robson EB. The incidence of rare alleles determining electrophoretic variants: data on 43 enzyme loci in man. Ann Hum Genet (London) 1974; 37: 237.
131. Strominger J, Engelhard VH, Fuks A, et al. Biochemical analysis of products of the MHC. In: Dorf ME, ed. The role of the major histocompatibility complex in immunobiology. New York: Garland, 1981: 115.
132. Kimball ES, Coligan JE. Structure of class I major histocompatibility antigens. Contemp Top Molec Immunol 1983; 9: 1.
133. Callahan GN, De Witt CW. Rat cell surface antigens: I. Isolation and partial characterization of an Ag-B antigen. J Immunol 1975; 114: 776.
134. Katagiri M, Natori T, Tanigaki N, Kreiter VP, Pressman D. Papain-solubilized Ag-B antigens: I. Isolation and characterization of two components composing Ag-B antigens. Transplantation 1975; 19: 230.
135. Sachs DH, Humphrey GW, Lunney JK. Sharing of Ia antigens between species: I. Detection of Ia specificities shared by rats and mice. J Exp Med 1977; 146: 381.
136. Shinohara N, Cullen SE, Sachs DH. Ag-B-linked analogue of Ia antigens in the rat. J Immunol 1977; 118: 2083.
137. Blankenborn EP, Cecka JM, Götze D, Hood L. Partial N-terminal amino acid sequence of rat transplantation antigens. Nature 1978; 274: 90.
138. Willoughby EM, Turner MJ, Sanderson AR. Incorporation of rat histocompatibility (AgB) antigens into liposomes, and their susceptibility to immune lysis. Eur J Immunol 1978; 8: 628.
139. Nilsson SF, Wigzell H. Isolation and partial characterization of rat lymphoid cell surface histocompatibility antigens and immunoglobulins. Scand J Immunol 1978; 7: 307.
140. Kvist S, Klareskog L, Peterson PA. Identification of H-2 and la-antigen analogues in several species by immunological cross reactions of xenoantisera. Scand J Immunol 1978; 7: 447.
141. Kvist S, Eriksson U, Peterson PA. Properties of purified papain-solubilized rat AgB antigens and reactivity of a xenoantiserum against the isolated antigens. Scand J Immunol 1980; 11: 63.
142. Sporer R, Black G, Rigiero C, Mason L, Götze D. The major histocompatibility complex of the rat, RTl: II. Biochemical evidence for a complex genetic organization. Immunogenetics 1978; 7: 507.
143. Sporer R, Manson LA, Götze D. A biochemical analysis of the membrane-associated gene products of major histocompatibility complex of the rat. J Immunol 1979; 122: 2162.
144. Haustein D, Günther E. Biochemical analysis of gene products of major histocompatibility recombinant haplotypes in the rat. Eur J Immunol 1980; 10: 615.
145. Misra DN, Noeman SA, Kunz HW, Gill TJ III. Production of monoclonal antibodies to rat MHC antigens using different myelomas. Transplant Proc 1981; 13: 1347.
146. Natori T, Ohhashi T, Kotani T, Katagiri M, Aizawa M. The molecular identification of two serologically defined gene products of the rat major histocompatibility complex. J Immunol 1979; 122: 1911.
147. Blankenborn EP, Götze D, Hood L. Genetic complexity of the rat MHC: biochemical evidence. In: Rat News Letter 1978; 4: 12.
148. Nathenson SG, Ewenstein BM, Brown JL, Nisizawa T, Uehara H, Sears DW. The structural-genetic relationships of the H-2K and H-2D products of the mouse major histocompatibility complex. In: Lerner RA, Bergsma D, eds. Birth defects. (Original Article Series, Vol. XIV) New York: A.R. Lies, 1978: 217.
149. Lafay F, Ewald SJ, McMillan M, Freiinger JA, Hood L. Tryptic peptide map analyses of mouse transplantation antigens. Immunogenetics 1981; 12: 21.
150. Lillehoj EP, Myers NB, Lee DR, Hansen TH, Coligan JE. Structural definition of a family of Ld-like molecules distributed among four of seven haplotypes compared. J Immunol 1985; 135: 1271.
151. Bell JI, Denny DW Jr, McDevitt HO. Structure and polymorphism of murine and human class II major histocompatibility antigens. Immunol Rev 1985; 84: 51.
152. Kappes DJ, Strominger JL. Structure and evolution of the HLA class II SX gene. Immunogenetics 1986; 24: 1.
153. Kaufman JF, Auffray C, Korman AJ, Shackelford DA, Strominger J. The class II molecules of the human and murine major histocompatibility complex. Cell 1984; 36: 1.
154. Giles RC, Capra JD. Structure, function, and genetics of human class II molecules. Adv Immunol 1985; 37: 1.
155. Korman AJ, Boss JM, Spies T, Sorrentino R, Okada K, Strominger JL. Genetic complexity and expression of human class II histocompatibility antigens. Immunol Rev 1985; 85: 45.
156. Shinohara N, Lunney JK, Sachs DH. Sharing of Ia antigens between species: II. Molecular localization of shared Ia determinants implies the existence of more than one I sublocus of the rat MHC. J Immunol 1978; 121: 637.
157. Blankenborn EP, Cecka JM, Freiinger J, Götze D, Hood L. Structure of Ia antigens from the rat: mouse alloantisera demonstrate at least two distinct molecular species. Eur J Immunol 1980; 10: 145.
158. Shinohara N, Sachs DA. Evidence for homologue of the. murine I-A and I-E loci in the rat MHC. J Immunol 1981; 126: 934.
159. Wettstein PJ, Freiinger JG, Hood L. Serological and biochemical characterization of rat (RTl) class II molecules with restricted mouse anti-la sera. Immunogenetics 1981; 13: 93.
160. McMaster WR, Williams AF. Identification of Ia glycoproteins in rat thymus and purification from rat spleen. Eur J Immunol 1979; 9: 426.
161. Fukumoto T, McMaster WR, Williams AF. Mouse monoclonal antibodies against rat major histocompatibility antigens: two Ia antigens and expression of Ia and class I antigens in rat thymus. Eur J Immunol 1982; 12: 237.
162. Bayer J, Reske K. Biochemical analysis of class II antigens. Identification of a two- and a three-polypeptide chain complex of I-A locus equivalent molecules in the rat. Eur J Immunol 1983; 13: 18.
163. Natori T, Ohhashi T, Inomata T, et al. Immunochemical evidence for multiple units of the class II molecule in the rat. J Immunogenet 1983; 10: 439.
164. Blankenborn EP, Symington FW, Pickard A, McKearn TJ. Monoclonal antibodies that distinguish rat Ia antigens and haplotypes. Transplant Proc 1983; 15: 1569.
165. Blankenborn EP, Symington FW, Cramer DV. Biochemical characterization of Ia antigens encoded by the RTLB and RT1.D loci in the rat MHC. Immunogenetics 1983; 17: 475.
166. Cecka JM, Blankenborn EP, Götze D, Hood L. Microsequence analysis of la antigens from three strains of rats. Eur J Immunol 1980; 10: 140.
167. Eccles SJ, McMaster WR. The structure of an RTl.Aß gene and expression of RTl class II molecules in nonlymphoid cells. Transplant Proc 1985; 17: 1801.
168. Robertson KA, McMaster WR. Complete structure of a rat RT1.Eβ chain: extensive conservation of MHC class II β-chains. J Immunol 1985; 135: 4095.
169. Wallis AE, McMaster WB. Sequence of a cDNA coding for a rat class IIΑ α chain: extensive DNA and protein sequence identify to H-2A« and HLA-DCla chains. Immunogenetics 1984; 19: 53.
170. McMaster WR, Wallis AE. Sequence analysis of DNA encoding RTl.Aa chains. Transplant Proc 1985; 17: 1797.
171. Holowachuk EW. Isolation and characterization of a cDNA clone for the MHC class II chain RT1.Dαu of the diabetic BB rat. Immunogenetics 1985; 22: 665.
172. Nathenson SG, Muramatsu T. Properties of the carbohydrate portion of mouse H-2 alloantigen glycoproteins. In: GA Jemie-son, TJ Greenwalt, eds. Glycoproteins of blood cells and plasma. Philadelphia: Lippincott, 1971: 245.
173. Coligan JE, Kindt TJ, Uehara H, Martinko J, Nathenson SG. Primary structure of a murine transplantation antigen. Nature 1981; 291: 35.
174. Kimball ES, Maloy WL, Coligan JE. Evidence for three carbohydrate prosthetic groups on mouse major histocompatibility antigens. Mol Immunol 1981; 18: 677.
175. Misra DN, Kunz HW, Cortese Hassett, A.L., Gill TJ III. Comparison of rat MHC class I antigens by peptide mapping. Transplant Proc (in press).
176. Brown JL, Kato K, Silver J, Nathenson SG. Notable diversity in peptide composition of murine H-2K and H-2D alloantigens. Biochemistry 1974; 13: 3174.
177. Maloy WL, Ozato K, Sachs DH, Coligan JE. Evidence for the association of I-A and I-E molecules in d-haplotype mice. Mol Immunol 1986; 23: 263.
178. Gustafsson K, Emmouth E, Widmark E, Böhme J, Peterson PA, Rask L. Isolation of a cDNA clone coding for an SB β-chain. Nature 1984; 309: 76.
179. Palmer M, Wettstein PJ, Freiinger JA. Evidence for extensive polymorphism of class I genes in the rat major histocompatibility complex (RTl). Proc Natl Acad Sci USA 1983; 80: 7616.
180. Günther E, Wurst W, Wonigeit K, Epplen JT. Analysis of the rat major histocompatibility system by Southern blot hybridization. J Immunol 1985; 134: 1257.
181. Steinmetz M, Freiinger JG, Fisher D, et al. Three cDNA clones encoding mouse transplantation antigens: homology to immunoglobulin genes. Cell 1981; 24: 125.
182. Steinmetz M, Moore KW, Freiinger JG, et al. A pseudogene homologous to mouse transplantation antigens: transplantation antigens are encoded by eight exons that correlate with protein domains. Cell 1981; 25: 683.
183. Carni B, Bregegere F, Abastodo JP, Kourilsky P. Multiple sequences related to classical histocompatibility antigens in the mouse genome. Nature 1981; 291: 673.
184. Cramer DV, Mowery PA, Hoffman S, Chakravarti A. Gene diversity in natural rat populations. Rat News Letter 1986; 17:19.
185. Steinmetz M, Winoto A, Minard K, Hood L. Clusters of genes encoding mouse transplantation antigens. Cell 1982; 28: 489.
186. Orr HT, Bach FH, Pleogh HL, Strominger JL, Kavathos P, Demars R. Use of HLA loss mutants to analyze the structure of the human major histocompatibility complex. Nature 1982; 296: 454.
187. Uitterlinden AG, Vijg J, Giphart MJ, Knook DL. Variation in restriction fragment length and methylation pattern of rat MHC class I genes. Exp Clin Immunogenet 1985; 2: 215.
188. Bjorck L, Krypsin-Sorensen I, Dyrberg T, Lernmark A, Kastern W. A deletion in a rat major histocompatibility complex class I gene is linked to the absence of β2-microglobulin-containing serum molecules. Proc Natl Acad Sci USA 1986; 83: 5630.
189. Maloy WL, Coligan JE, Barra Y, Jay G. Detection of a secreted form of the murine H-2 class I antigen with an antibody against its predicted carboxyl terminus. Proc Natl Acad Sci USA 1984; 81: 1216.
190. Palmer MJ, Buck DA, Freiinger JA, Wettstein PS. Polymorphic class II sequences linked to the rat major histocompatibility complex (RTl) homologous to human DR and DQ sequences. J Immunol 1985; 135: 1450.
191. Sawicki JA, Wettstein PJ. Evidence for extensive polymorphism of class II molecules in the rat. J Immunol 1984; 132: 310.
192. Wettstein PJ, Faas S, Buck D. Class I and class II restriction pattern polymorphisms associated with independently derived RTl haplotypes in inbred rats. Immunogenetics 1985; 22: 9.
193. Eccles S, McMaster WR. DNA sequence analysis of a rat RTl class II Α β gene. Immunogenetics 1985; 22: 653.
194. Schüller J, Lernmark A. Isolation of a rat immune response gene identical to an alleged mouse A class II β-chain pseudogene. Immunogenetics 1985; 22: 601.
195. Larhammar D, Hammerling V, Denaro M, et al. Structure of the murine immune response I-A locus: Sequence of the I-A gene and an adjacent β-chain second domain exon. Cell 1983; 34: 179.
196. Konoeda Y, Terasaki PI, Wakisaka A, Park MA, Mickey MR. Public determinants of HLA indicated by pregnancy antibodies. Transplantation 1986; 41: 253.
197. Stranick KS, Ho HN, Macpherson TA, Locker J, Kunz HW, Gill TJ III. Regulation of the maternal-fetal response by trophoblast antigen expression. In: Clark DA, Croy BA, eds. Reproductive immunology 1986. Amsterdam: Elsevier, 1986: 45.
198. Scofield VL, Schlumpberger JM, West LA, Weissman I. Proto-chordate allorecognition is controlled by an MHC-linked gene system. Nature 1982; 295: 499.