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Volumn 45, Issue 2-4, 1987, Pages 171-205

Pathobiochemical mechanisms of hepatocellular damage following lipid peroxidation

Author keywords

4 hydroxyalkenals; calcium; covalent binding; haloalkanes; hepatocellular damage; iron; lipid peroxidation; lysophosphatides; membrane fluidity; phospholipase A2; plasma membrane; secondary pathological mechanisms

Indexed keywords

4 HYDROXYALKENAL; HALOGENOALKANE; UNCLASSIFIED DRUG;

EID: 0023200386     PISSN: 00093084     EISSN: None     Source Type: Journal    
DOI: 10.1016/0009-3084(87)90065-X     Document Type: Article
Times cited : (44)

References (129)
  • 7
    • 0020614088 scopus 로고
    • A new direction in the study of carbon tetrachloride hepatotoxicity
    • (1983) Life Sciences , vol.33 , pp. 401-408
    • Recknagel1
  • 10
    • 0015127172 scopus 로고
    • Liver parenchymal cell injury. VII. Membrane denaturation following carbon tetrachloride.
    • (1971) Lab Invest , vol.25 , pp. 269-278
    • Reynolds1    Ree2
  • 14
    • 0019201288 scopus 로고
    • Possible role of endogenous toxigenic lipids in the carbon tetrachloride poisoned hepatocyte.
    • (1980) Fed Proc , vol.39 , pp. 3134-3137
    • Willis1
  • 24
    • 0017279368 scopus 로고
    • Calcium uptake of a rat liver microsomal subcellular fraction in response to in vivo administration of carbon tetrachloride.
    • (1976) J Biol Chem , vol.251 , pp. 1197-1201
    • Moore1    Davenport2    Landon3
  • 27
    • 0022507160 scopus 로고
    • Elevated cytosolic calcium in rat hepatocytes exposed to carbon tetrachloride.
    • (1986) J Pharmacol Exp Ther , vol.238 , pp. 186-191
    • Long1    Moore2
  • 28
    • 0023028709 scopus 로고
    • Inhibition of liver endoplasmic reticulum calcium pump by CCl4 and release of a sequestered calcium pool
    • (1986) Biochemical Pharmacology , vol.35 , pp. 4131-4137
    • Long1    Moore2
  • 29
    • 0020639491 scopus 로고
    • Interrelationship between in vivo lipid peroxidation, microsomal Ca2+-sequestration activity and hepatotoxicity in rats treated with carbon tetrachloride, cumene hydroperoxide or thioacetamide.
    • (1983) Res Commun Chem Pathol Pharmacol , vol.40 , pp. 405-415
    • Younes1    Albrecht2    Siegers3
  • 35
    • 0019813623 scopus 로고
    • Dependence of the carbon-tetrachloride--induced death of cultured hepatocytes on the extracellular calcium concentration.
    • (1981) Am J Pathol , vol.105 , pp. 138-148
    • Casini1    Farber2
  • 46
    • 0017091058 scopus 로고
    • Lipid peroxidation and alteration of membrane lipids in isolated hepatocytes exposed to carbon tetrachloride.
    • (1976) J Biol Chem , vol.251 , pp. 4973-4978
    • Weddle1    Hornbrook2    McCay3
  • 51
    • 0020957706 scopus 로고
    • Halothane Hepatotoxicity: Relation Between Metabolic Activation, Hypoxia, Covalent Binding, Lipid Peroxidation and Liver Cell Damage
    • (1983) Hepatology , vol.3 , pp. 601-606
    • de Groot1    Noll2
  • 54
    • 0004276105 scopus 로고
    • R.S. Sohal, Elsevier/North Holland Biochemical Press, Amsterdam
    • (1981) Age Pigments , pp. 63-81
    • Donato1
  • 55
    • 0019920815 scopus 로고
    • Metabolism of malonaldehyde in vivo and in vitro
    • (1982) Lipids , vol.17 , pp. 349-355
    • Sin1    Draper2
  • 60
    • 0018745714 scopus 로고
    • Toxic substances and cell membrane function.
    • (1979) Fed Proc , vol.38 , pp. 2220-2225
    • Pritchard1
  • 65
    • 0018695638 scopus 로고
    • Formation of carbonyl chloride in carbon tetrachloride metabolism by rat liver in vitro.
    • (1979) Cancer Res , vol.39 , pp. 3942-3947
    • Shah1    Hatman2    Weinhouse3
  • 70
    • 0019367710 scopus 로고
    • Effects of cysteine and cystamine on the carbon tetrachloride induced decrease in arachidonic acid content of rat liver microsomal phospholipids
    • (1981) Toxicology , vol.19 , pp. 77-82
    • de Toranzo1    Marzi2    Castro3
  • 74
    • 0019124087 scopus 로고
    • Calcium modulates the lipid dynamics of rat hepatocyte plasma membranes by direct and indirect mechanisms
    • (1980) Biochemistry , vol.19 , pp. 4823-4827
    • Livingstone1    Schachter2
  • 75
    • 0021759016 scopus 로고
    • Influence of phospholipid peroxidation on the phase behavior of phosphatidylcholine and phosphatidylethanolamine in aqueous dispersions
    • (1984) Biochemistry , vol.23 , pp. 4969-4977
    • van Duijn1    Verkleij2    de Kruijff3
  • 79
    • 0019362816 scopus 로고
    • Phosgene: A possible role in the potentiation of carbon tetrachloride hepatotoxicity by 2-propanol
    • (1981) Life Sciences , vol.29 , pp. 503-507
    • Harris1    Anders2
  • 85
    • 0021842533 scopus 로고
    • Separation and characterization of the aldehydic products of lipid peroxidation stimulated by carbon tetrachloride or ADP-iron in isolated rat hepatocytes and rat liver microsomal suspensions.
    • (1985) Biochem J , vol.227 , pp. 629-638
    • Poli1    Dianzani2    Cheeseman3    Slater4    Lang5    Esterbauer6
  • 89
    • 0021846750 scopus 로고
    • Metabolism of the lipid peroxidation product 4-hydroxynonenal by isolated hepatocytes and by liver cytosolic fractions.
    • (1985) Biochem J , vol.228 , pp. 363-373
    • Esterbauer1    Zollner2    Lang3
  • 94
    • 0022003008 scopus 로고
    • Vitamin E reversal of the effect of extracellular calcium on chemically induced toxicity in hepatocytes
    • (1985) Science , vol.227 , pp. 751-754
    • Fariss1    Pascoe2    Reed3
  • 100
    • 0020027621 scopus 로고
    • Epinephrine inhibits protein synthesis in isolated mouse hepatocytes through alpha adrenergic receptors in a calcium dependent way
    • (1982) Biochemical Pharmacology , vol.31 , pp. 1656-1658
    • Mandl1    Grazo2    Antoni3
  • 113
    • 0014958799 scopus 로고
    • The Fusion of Biological Membranes
    • (1970) Nature , vol.227 , pp. 815-817
    • Lucy1
  • 119
    • 0019474177 scopus 로고
    • Association of lipid peroxidation and polymerization of membrane proteins with erythrocyte aging.
    • (1981) Fed Proc , vol.40 , pp. 183-188
    • Hochstein1    Jain2
  • 123
    • 0023215797 scopus 로고
    • No evidence for lysophospholipid formation during peroxidation of phospholipids by NADPH-cytochrome P-450 reductase and iron ions
    • (1987) Archives of Toxicology , vol.60 , pp. 170-173
    • Kostrucha1    Kappus2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.