Amphidinolide-B, a novel macrolide with potent antineoplastic activity from the marine dinoflagellate Amphidinium sp.

Journal of the Chemical Society, Chemical Communications

Volumn , Issue 14, 1987, Pages 1127-1129

  Ishibashi, Masami ^a   Ohizumi, Yasushi ^a   Hamashima, Mari ^a   Nakamura, Hideshi ^a   Hirata, Yoshimasa ^b   Sasaki, Takuma ^c   Kobayashi, Jun'ichi ^a  

^a MITSUBISHI KASEI INST OF LIFE SCI   (Japan)

^b MEIJO UNIVERSITY   (Japan)

^c KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIDINOLIDE B; NEW DRUG;

BLOOD AND HEMOPOIETIC SYSTEM; DRUG COMPARISON; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; IN VITRO STUDY; INTOXICATION; INVERTEBRATE; LEUKEMIA L 1210; MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRELIMINARY COMMUNICATION;

EID: 0023199410     PISSN: 00224936     EISSN: None     Source Type: Journal    
DOI: 10.1039/C39870001127     Document Type: Article

References (20)

1. Dinoflagellates: Y. Shimizu, ‘Marine Matural Products,’ ed. P. J. Scheuer, Academic Press, New York, 1978, vol. I, p. 1.
2. Y. Shimizu, H. Bando, H.-N. Chou, G. Van Duyne, and J. C. Clardy, J. Chem. Soc., Chem. Commun., 1986, 1656.
3. M. S. Lee, D. J. Repeta, K. Nakanishi, and M. G. Zagorski, J. Am. Chem. Soc., 1986, 108, 7855.
4. T. Yasumoto, M. Murata, Y. Oshima, M. Sano, G. K. Matsumoto, and J. Clardy, Tetrahedron, 1985, 41, 1019.
5. Bacteria: T. Yasumoto, D. Yasumura, M. Yotsu, T. Michishita, A. Endo, and Y. Kotaki, Agric. Biol. Chem., 1986, 50, 793.
6. T. Kosuge, T. Tsujki, K. Hirai, and T. Fukuyama, Chem. Pharm. Bull., 1985, 33, 3059.
7. Cyanophytes: J. H. Cardellina II, F.-J. Marner, and R. E. Moore, Science, 1979, 204, 193.
8. M. Ishibashi, R. E. Moore, G. M. L. Patterson, C. Xu, and J. Clardy, J. Org. Chem., 1986, 51, 5300.
9. J. Kobayashi, H. Nakamura, Y. Ohizumi, and Y. Hirata, Tetrahedron Lett., 1986, 27, 1191.
10. J. Kobayashi, Y. Ohizumi, H. Nakamura, and Y. Hirata, Tetrahedron Lett., 1986, 27, 2113.
11. J. Kobayashi, Y. Ohizumi, H. Nakamura, Y. Hirata, K. Wakamatsu, and T. Miyazawa, Experientia, 1986, 42, 1064.
12. J. Kobayashi, Y. Ohizumi, H. Nakamura, and Y. Hirata, Experientia, 1986, 42, 1176.
13. M. Ishibashi, Y. Ohizumi, T. Sasaki, H. Nakamura, Y. Hirata, and J. Kobayashi, J. Org. Chem., 1987, 52, 450.
14. J. Kobayashi, M. Ishibashi, H. Nakamura, Y. Ohizumui, T. Yamasu, T. Sasaki, and Y. Hirata, Tetrahedron Lett., 1986, 27, 5755.
15. I. Nakajima, Y. Oshima, and T. Yasumoto, Bull. Jpn. Soc. Sci. Fish., 1981, 47, 1029.
16. L. Provasoli, in ‘Culture and Collection of Algae,’ eds. A. Watanabe and A. Hattori, Japan Soc. Plant Physiol., Tokyo, 1968, p. 63.
17. J. J. Barchi, Jr., R. E. Moore, and G. M. L. Patterson, J. Am. Chem. Soc., 1984, 106, 8193.
18. A. Bax, A. Aszalos, Z. Dinya, and K. Sudo, J. Am. Chem. Soc., 1986, 108, 8056.
19. L. A. Dolak, F. Reusser, L. Baczynskj, S. A. Mizsak, B. R. Hannon, and T. M. Castle, J. Antibiot., 1983, 36, 13.
20. A. Bax and R. Freeman, J. Mag. Reson., 1981, 44, 542.