5-HT receptor binding in post-mortem brain from patients with affective disorder

Journal of Affective Disorders

Volumn 13, Issue 1, 1987, Pages 67-74

  McKeith, I G ^a   Marshall, E F ^a   Ferrier, I N ^b   Armstrong, M M ^a   Kennedy, W N ^a   Perry, R H ^c   Perry, E K ^c   Eccleston, D ^a  

^a ROYAL VICTORIA INFIRMARY   (United Kingdom)

^b MRC Neuroendocrinology Unit ^*  (United Kingdom)

^c NEWCASTLE GENERAL HOSPITAL   (United Kingdom)

Author keywords

(Affective disorder); 5 HT receptor binding; Post mortem brain

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; SEROTONIN;

ADULT; AFFECTIVE NEUROSIS; AUTOPSY; BRAIN CORTEX; CENTRAL NERVOUS SYSTEM; CYTOLOGY; DYSTHYMIA; HUMAN; MELANCHOLIA; PSYCHOLOGICAL ASPECT;

AGED; AGED, 80 AND OVER; ANTIDEPRESSIVE AGENTS; BRAIN; DEPRESSIVE DISORDER; FEMALE; FRONTAL LOBE; HUMANS; KETANSERIN; MALE; RECEPTORS, SEROTONIN; SEROTONIN; TRITIUM;

EID: 0023199181     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-0327(87)90075-9     Document Type: Article

References (36)

1. Biochemical evidence of selective nerve cell changes in the normal ageing human and rat brain
2. CSF monoamine metabolites in melancholia
3. Changes on recovery in the concentrations of tryptophan and the biogenic amine metabolites in the CSF of patients with affective illness
4. A hundred cases of suicide: clinical aspects
5. Determination of monoamine and monoamine metabolites in the human brain: post-mortem studies in a group of suicides and in a control group
6. Characterisation and localisation of serotinin receptors in human brain post-mortem
7. Nordrenaline 5-hydroxytryptamine and 5-hydroxyindolacetic acid in hindbrains of suicidal patients
8. Tritiated imipramine binding sites are decreased in platelets of untreated depressed patients
9. Regional serotonin levels in brain: a comparison of depressive suicides and alcoholic suicides with controls
10. Neurotransmitter receptors and monoamine metabolites in the brains of patients with Alzheimer-type dementia and depression, and suicides,
11. Monoamines, rewards and punishments: the anatomy and physiology of the effective disorders
12. 2 receptor sites on human blood platelets
13. Post-mortem neurochemical studies in depression
14. Potentiation of a monoamine oxidase inhibitor by tryptophan
15. 2 receptor mediated head twitch behaviour following antidepressant treatment on mice
16. 2 antagonist pirenperone
17. Simultaneous quantification of dopamine, 5-HT and four metabolically related compounds by means of reversed phase high performance liquid chromatography with electrochemical detection
18. Serotonin and 5-hydroxyindoleacetic acid in brains of suicide victims
19. Serotonin receptor binding sites
20. 3H ligand for serotonin (S2) receptor binding and functional role
21. Protein measurement with the Folin phenol reagent
22. 2 and β-adrenergic receptor binding in the frontal cortices of suicide victims
23. Serotonin-2 binding sites in human frontal cortex and hippocampus
24. Whole blood serotonin and plasma tryptophan using high pressure liquid chromatography with electrochemical detection
25. Effects of antidepressant drugs on serotonin receptor mechanisms
26. 2 receptors and suicide
27. Serotonergic mechanisms in brains of suicide victims
28. Depressed patients have decreased binding in tritiated imipramine to platelet serotonin ‘transporter’
29. Long term antidepressant treatment decreased spiperidol labelled serotoninrreceptor binding
30. Decreased imipramine binding in the brains of patients with depressive illness
31. Effect of amitriptyline and imipramine on the concentration of 5-HIAA in the cerebrospinal fluid of depressed patients
32. Increased serotonin-2 binding in frontal cortex of suicide victims
33. Decreased uptake of 5-hydroxytryptamine in blood platelets from depressed patients
34. Management of depression with serotonin precursors
35. Potentiation of the antidepressant action of clomipramine by tryptophan