The Retinoids: A Review of their Clinical Pharmacology and Therapeutic Use

Drugs

Volumn 34, Issue 4, 1987, Pages 459-503

  Orfanos, C E ^a   Ehlert, R ^a   Gollnick, H ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AROTINOID; ETRETIN; ETRETINATE; ISOTRETINOIN; MOTRETINIDE; RETINOIC ACID;

ACNE; ADVERSE DRUG REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; BLOOD AND HEMOPOIETIC SYSTEM; BONE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; DOSE RESPONSE; DRUG EFFICACY; DRUG INDICATION; DRUG MECHANISM; DRUG RESPONSE; EMBRYO; EMBRYOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; INTOXICATION; MAMMAL; MELANOMA; MOUSE; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; PSORIASIS; REVIEW; THERAPY; TOPICAL DRUG ADMINISTRATION;

DRUG INTERACTIONS; HUMAN; NEOPLASMS; PUVA THERAPY; RETINOIDS; SKIN DISEASES;

EID: 0023193244     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.2165/00003495-198734040-00003     Document Type: Review

References (425)

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4. Treatment of ichthyosis with isotretinoin
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8. Retinoide und Immunologie; Physiologische und pharmakologische Wirkungen natürlicher und synthetischer Retinoide auf die Immunantwort
9. Trimethylmethoxyphenyl-retinoic acid (Ro 10-1670) inhibits mitogen-induced DNA-synthesis in peripheral blood lymphocytes in vitro
10. Effect of synthetic retinoids on human peripheral blood lymphocytes and polymorphonuclears in vitro
11. Granulozyten-Mirgration in vitro bei Psoriasis-Patienten unter aromatischem Retinoid
12. Impaired motility and random migration of vital polymorphonuclears in vitro after therapy with aromatic retinoid in psoriasis
13. Kutan disseminierter LE. Therapie mit aromatischem Retinoid
14. Akantholyse und eosinophile Spongiose bei Pemphigus herpetiformis: Erfolgreiche Retinoidtherapie
15. Etretinat bei hyperkeratotisch-rhagadiformem Hand- und Fuβekzem
16. Untersuchungen über die Wirksamkeit der Vitamin-A-Säure
17. Hyperkeratotic porokeratosis (Mibelli) with psoriasis — response to an aromatic retinoid
18. Kombinierte Therapie der Psoriasis mit einem aromatischen Retinoid (Ro 10-9359) und UVB-Bestrahlungen
19. Reiter’s disease: successful treatment of the skin manifestations with oral etretinat
20. Results of oral retinoid therapy in different forms of psoriasis
21. The treatment of keratosis palmaris et plantaris with isotretinoin
22. Aromatic retinoid in the treatment of multiple superficial basal cell carcinoma, arsenic keratosis and kerato-acanthoma
23. Immunological features of psoriasis: effects of Ro 10-9359, concanavalin A, pokeweed mitogen and methotrexate on cultivated lymphocytes
24. Behandlung von Larynxpachydermien mit aromatischem Retinoid (Ro 10-9359)
25. Systemic treatment of Darier’s disease with a new retinoid (Ro 10-9359)
26. A controlled multicentre study of Ro 10-9359 in association with topical corticosteroid therapy in psoriasis
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30. Ultrastructural study of the four main types of ichthyosis after one month’s treatment with Ro 10-9359
31. Hyperplasie sébacée acquise sensible an 13-cis-retinoide
32. Erythrokeratodermia congenitalis progressiva symmetrica Gottron
33. Vitamin A-Säure in der Tumortherapie: tierexperimentelle Untersuchungen über die Wirkung von Vitamin A-Säure auf Tumoren
34. From vitamin A to retinoids: chemical and pharmacological aspects
35. New retinoids with potential use in humans
36. The future of the retinoids
37. Action positive de l’etretinate dans un cas de pemphigus bénigne familial
38. Die Beeinflussung der Arthropathia psoriatica und der chronischen Polyarthritis durch ein oral wirksames aromatisches Retinoid
39. Psoriasiforme Epidermis-Reaktion der Meerschweinschenhaut durch örtliche Vitamin A-Säure-Applikation
40. Tumorprophylaxe bei Xeroderma pigmentosum mit aromatischem Retinoid (Ro 10-9359)
41. Papillon-Lefèvre syndrome: report of a case treated with oral retinoid Ro 10-9359
42. Pharmacokinetics of the retinoids isotretinoin and etretinate
43. Pharmacokinetics of isotretinoin during repetitive dosing in patients
44. Confluent and reticulated papillomatosis successfully treated with the aromatic etretinate
45. Disseminated porokeratosis Mibelli treated with Ro 10-9359
46. Diffuse hyperostosis associated with etretinate
47. Premature sebaceous gland hyperplasia: successful treatment with isotretinoin
48. The effects of retinoids on neutrophil functions in vitro
49. Variant of keratoderma hereditaria mutilans (Vohwinkel’s syndrome). Treatment with orally administered isotretinoin
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52. The retinoic acid derivative Ro 11-11430 (Tasmaderm®) in patients with acne vulgaris not tolerating retinoic acid
53. The retinoic acid derivative Ro 11-1430 in acne vulgaris: a controlled multicenter trial against retinoic acid
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55. Xeroderma pigmentosum et traitement au long Cours par le rétinoide aromatique
56. Treatment of cutaneous T-cell lymphoma with retinoids
57. Treatment of lichen planus and leukoplakia with the oral retinoid Ro 10-9359
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59. The role of etretinate in the management of keratoacanthoma
60. 13-cis-retinoic acid in acne — mechanism of action
61. Vitamin A acid in the topical treatment of warts
62. Retinoids and the immune system: immunostimulation by vitamin A
63. Treatment of psoriasis and other dermatoses with a new aromatic retinoid (Ro 10-9359)
64. Oral synthetic retinoid treatment in children
65. Isotretinoin treatment of Darier’s disease
66. Eruptive xanthomas associated with isotretinoin (13-cis-retinoic acid)
67. Epidermale Zeilproliferation unter oraler Retinoid-Therapie bei Psoriasis
68. Inhibition of neutrophil migration by etretinate and its main metabolite
69. Pachyonychie congenitale. Description de 3 cas familiaux-traitment par le retinoide aromatique (Ro 10-9359)
70. Erfahrungen mit der systemischen Retinoidbehandlung bei Lichen ruber planus
71. Vitamin A acid in liehen planus
72. Effects of retinoids on growth and dissemination of malignant tumours: immunological considerations
73. Treatment of epidermodysplasia verruciformis or multiple verrucae planae by oral aromatic retinoid (Ro 10-9359 — Tigason)
74. Klinische Untersuchung eines aromatischen Retinoids (Ro 10 9359) zur Behandlung oraler Hyperkeratosen
75. Responses of epidermal polyamines to orally administered aromatic retinoid Ro 10-9359
76. Retinoids, cancer and the skin
77. Retinoid-stimulated material in psoriatic epidermis during Ro 10-9359 therapy
78. Isotretinoin therapy is associated with early skeletal radiographic changes
79. Effects of retinoids on ultraviolet-induced carcinogenesis
80. Pyogenic granuloma-like acne lesions during isotretinoin therapy
81. Psoriasis: a review of recent advances in treatment
82. The treatment of severe cystic acne with 13-cis-retinoic acid
83. The treatment of erosive lichen planus with a retinoid-etretinate
84. Effect of retinoic acid on the clonal growth of childhood myeloid and lymphoid leukemias: a pediatric oncology group study
85. Treatment of erythrokeratoderma variabilis with oral synthetic retinoids
86. Etretinate in the treatment of juvenile pityriasis rubra pilaris
87. Histologic changes in the liver during etretinate treatment
88. A randomised trial of etretinate (Tigason®) in palmoplantar pustulosis
89. Subcorneal pustular dermatosis (Sneddon-Wilkinson) — therapeutic problems
90. Tolerance du rétinoide aromatique: recherche d’une toxicité sur les functions hémato-poiétique, rénale et thyroidienne. Interactions avec le métabolisme des rétinoides naturels
91. Hypercalcemia and skeletal effects in chronic hypervitaminosis
92. Severe psoriasis — oral therapy with a new retinoid
93. Oral treatment of pustulosis palmoplantaris with a new retinoid Ro 10-9359
94. Therapeutische Versuche bei Psoriasis mit Vitamin A. Zugleich ein Beitrag zur Vitamin A-Hypervitaminose
95. Erythrokeratodermia flgurata variabilis Mendes da Costa: Erfolgreiche Behandlung mit einem oralen aromatischen Retinoid (Ro 10-9359)
96. Photochemotherapie bei Psoriasis. Steigerung der Wirksamkeit durch ein orales aromatisches Retinoid
97. Response of epidermal cell proliferation to orally administered aromatic retinoid
98. Response of psoriatic arthropathy to arotinoid (Ro 13-6298), a pilot study
99. The use of isotretinoin in rosacea
100. Influence of retinoid Ro 10-9359 on cell-mediated immunity in vivo
101. The effect of aromatic retinoid Ro 10-9359 (etretinat) on finger nail growth
102. Clinical evaluation of an aromatic retinoid, Ro 10 1670, in severe psoriasis
103. Changes in lipid metabolism during retinoid administration
104. Vertebral abnormalities in patients receiving synthetic retinoids. Abstract
105. Lack of skeletal radiographic changes during short-term etretinate therapy for psoriasis
106. Coordinate control by vitamin A of keratin gene expression in human keratinocytes
107. Evaluation of 13-cis-retinoic acid in lamellar ichthyosis, pityriasis rubra pilaris and Darier’s disease
108. Influence of oral retinoid on the cell kinetics of normal human epidermis
109. Ultrastructural survey and tissue analysis of human livers after 6-month course of etretinate
110. Systemic treatment of psoriasis with a new aromatic retinoid
111. Influence of a new retinoid Ro 10-9359 on the cytochrome P-450 system and other enzymes in rat’s liver
112. Phase I clinical trial of 13-cis-retinoic acid in myelodysplastic syndromes
113. Pityriasis rubra pilaris — response to 13-cis-retinoic acid (isotretinoin)
114. Comparative effect of isotretinoin and etretinate on acne and sebaceous gland secretion
115. Elevated levels of triglycerides in patients with skin diseases treated with oral aromatic retinoid: the significance of risk factors
116. 13-cis-Retinsäure
117. Therapie mit Tigason® — Ratschläge zum praktischen Vorgehen
118. Klinisch-therapeutischer Index und Dosimetrie der oralen Benhandlung mit aromatischem Retinoid — Ein Vergleich unterschiedlicher Dosierungen
119. Etretinat: Pro und Contra. Nutzen-Risiko-Abwägung der systemischen Retinoidtherapie bei Psoriasis und neuere Entwicklungen. Freie aromatische Säure, Arotinoide
120. Clinical efficacy of retinoids: European experiences
121. Retinoids
122. Unerwünschte Wirkung der Retinoide — das Nebenwirkungsspektrum
123. Alterations of lipid metabolism under treatment with oral retinoids (isotretinoin and etretinate)
124. Retinoids and blood lipids: an update and review
125. Verhalten der lipolytischen Aktivität des Serums vor und unter 13-cis-Retinsäure bei parenteraler Fettbelastung
126. Risk factors promote elevations of serum lipids in acne patients under oral 13-cis-retinoic acid (isotretinoin)
127. Differential effect of 13-cis-retinoic acid and an aromatic retinoid (Ro 10-9359) on the sebaceous glands of the hamster flank organ
128. Effect of 13-cis-retinoic acid on the hamster flank organ
129. Vitamin A transport and delivery and the mechanism of vitamin A toxicity
130. Vitamin A and retinoids in health and disease
131. Retinoid binding proteins in plasma and cells
132. Degree of bronchial metaplasia in heavy smokers and its regression after treatment with a retinoid
133. Isotretinoin for the treatment of sebaceous hyperplasia
134. Long-term inhibition of quantitative sebum production with isotretinoin
135. Treatment of psoriasis by oral PUVA therapy combined with aromatic retinoid L (Ro 10-9359)
136. Retinoid combinations
137. Topical administration of vitamin A acid (retinoic acid) in palmar keratosis: callosities, hyperkeratotic eczema, hypertrophic lichen planus, pityriasis rubra pilaris
138. The therapeutic value of retinoic acid in chronic discoid, acute guttäte and erythrodermic psoriasis: clinical observations on twenty-five patients
139. Vitamin A acid in treatment of oral lichen planus
140. Traitément oral des psoriasis graves par un nouveau rétinoide aromatique (Ro 10-9359)
141. Langhans cells in skin from patients with psoriasis: quantitative and qualitative study of T6 and HLA-DR antigen-expressing cells and changes with aromatic retinoid administration
142. Keratosis palmaris et plantaris cum degeneratione granulosa Vörner
143. Lokale und systemische Therapie mit alltrans-Retinsäure in der Dermatologie
144. Der Metabolismus des Retinoids 10-9359. Isolierung und Identifizierung der Hauptmetaboliten aus Plasma, Urin and Faezes des Menschen sowie der Galle der Ratte
145. Pharmacokinetic and metabolic pathways of systemically applied retinoids
146. Systemic retinoid therapy of systematized verrucous epidermal naevus
147. Etretinat bei Genodermatosen und verschiedenen entzündlichen Hautkrankheiten
148. Teratogene Wirkung von Etretinat beim Menschen
149. The relapses of cystic acne after isotretinoin treatment are age-related: a long-term follow-up study
150. Arotinoid Ro 13-6298 and etretin: two new retinoids inferior to isotretinoin in sebum suppression and acne treatment
151. Acne fulminans. Tratamento de 11 patientes com o acido 13-cis-retinoica
152. The influence of topical and oral retinoid treatment on photocarcinogenicity in hairless albino mice
153. Treatment of keratoacanthomas with oral 13-cis-retinoic acid
154. Depression — a side effect of 13-cis-retinoic acid therapy. Correspondence
155. Therapy of psoriasis with retinoid plus PUVA — clinical and histologie data
156. Effect of retinoids on collagen production by chondrocytes in culture
157. Effect of vitamin A and its derivatives on collagen production and chemotactic response of fibroblasts
158. Keratosis palmaris et plantaris. Treatment with topically applied vitamin A acid
159. Grover’s disease treated with isotretinoin. Report of four cases
160. Retinoids activate Superoxide production by polymorphonuclear leucocytes
161. 13-Cis-retinoic acid in conglobate acne. A follow-up study of 14 trial centers
162. In vivo immunostimulating properties of two retinoids: Ro 10-9359 and Ro 13-6298
163. Severe oral lichen planus: treatment with an aromatic retinoid (etretinate)
164. Hypertroph-verhornende Variante des Morbus Darier. Erfolgreiche orale Behandlung mit einem aromatischen Retinoid (Ro 10-9359)
165. Isotretinoin-PUVA for psoriasis. Correspondence
166. A double-blind controlled trial of etretinate (Tigason®) and ibuprofen in psoriatic arthritis
167. Treatment of rosacea with isotretinoin
168. Systemische Retinoid-Therapie mit Etretinat bei Pachyonychia congenita
169. Studies in reproductive toxicology and mutagenicity with Ro 10-9359
170. Vitamin-A-Säure-Therapie von Mollusca contagiosa bei Haemophilie A
171. Richner-Hanhart-Syndrome (RHS) — tyrosinaemia type II and oral aromatic retinoid (Ro 10-9359). Report of two cases
172. Retinoid-orale Photochemotherapie (Re PUVA) als Kombinationsbehandlung bei Mycosis fungoides
173. Sur un cas de mycosis fungoide avec manifestations tumorales traité avec Ro 10-9359 (Tigason®)
174. Zur Lokalbehandlung von Verrucae planae juveniles und Verrucae vulgares mit Vitamin-A-Säure
175. Ro 10-9359 in epidermodysplasia verruciformis: preliminary report
176. Aromatic retinoids in psoriasis: clinical, histological, electron microscopical, and immunological investigations
177. Treatment of Gram negative folliculitis with isotretinoin
178. Peroral aromatic retinoid treatment of palmoplanter pustulosis: double-blind comparison of Ro 10-9359 and placebo
179. Report of a family with mal de Meleda in Taiwan
180. 13-Cis-retinoic acid and acne
181. A follow-up study of 13-cis-retinoic acid therapy in cystic acne
182. 13-Cis-retinoic acid in acne (a double-blind study of dose-response)
183. A comparative study of 13-cis-retinoic acid and erythromycin therapy in severe acne
184. Toxicology, carcinogenicity and teratogenicity of some orally administered retinoids
185. Prolonged serum cholesterol elevations during etretinate therapy for psoriasis are predicted by abnormal pretherapy triglyceride levels. Abstract
186. Etretinate therapy for psoriasis: clinical responses, remission times, epidermal DMA and polyamine responses
187. Treatment of disseminated superficial actinic porokeratosis with a new aromatic retinoid (Ro 10-9359)
188. Influence of 13-cis-retinoic acid on Zymosan-induced chemiluminescence of granulocytes
189. Treatment of acanthosis nigricans with oral isotretinoin
190. Isotretinoin treatment of recalcitrant warts in an immunosuppressed man
191. Pharmacology of 13-cis-retinoic acid in humans
192. Treatment of cutaneous T-cell lymphoma (mycosis fungoides) with 13-cis-retinoic acid
193. Retinoids in superficial bladder tumours: update
194. Embryonale Fehlbildung bei Etretinat-Therapie der Mutter wegen M. Darier
195. A double-blind study of the effects of 13-cis-retinoic acid on acne, sebum excretion rate and microbial population
196. Effects of an arotinoid (Ro 13-6298) in the treatment of multiple kératoses and squamous cell epitheliomata
197. Teratogenesis and reproductive safety evaluation of the retinoid etretin Ro 10-1670
198. No influence of three synthetic retinoids (Ro-10-1670, Ro 4-4780, Ro 13-6298) on lipoxygenase activity in two in vitro systems
199. Biochemical treatment of precancerous oral lesions: the effectiveness of various analogues of retinoid acid
200. Effect of retinoids on precancerous lesions of oral mucosa
201. Aromatisches Retinoid-orale Photochemotherapie (Re-PUVA) bei chronisch-vegetierender Pyodermie
202. A case of Kyrle’s disease, responding to treatment with Tigason®. Abstract
203. Vitamin-A-Säure zur Lokalbehandlung epithelialer Neoplasien
204. Retinoic acid embryopathy
205. Inhibitory effects of 13-cis-retinoic acid on human sebaceous glands
206. 13-Cis-retinoic acid and tetracycline versus 13-cis-retinoic acid alone in the treatment of nodulocystic acne
207. Prevention and reversal by a retinoid of 3,4 benzpyrene- and cigarette smoke condensate-induced hyperplasia and metaplasia of rodent epithelia in organ culture
208. (zitiert aus Frank M). Zur Frage der Resistenzverminderung gegen Infektionen bei der A-Avitaminose
209. Systemic treatment of psoriasis with an oral retinoic acid derivative (Ro 10-9359)
210. Motretinide versus benzoyl peroxide in the treatment of acne vulgaris
211. Efficacy of etretinate in clearing and prevention of relapse of palmoplantar pustulosis
212. Treatment of pityriasis rubra pilaris with an oral aromatic retinoid (Ro 10-9359). A clinical and light and electron microscopic study
213. Reduction of increased polyamine levels in psoriatic lesions by retinoid and PUVA treatments
214. Psoriatic arthritis
215. Erythrodermia congenitalis progressiva symmetrica Gottron
216. N-(4-hydroxyphonyl) retinamide: a synthetic analog of vitamin A that is a potent inhibitor of prostaglandin biosynthesis
217. Oral isotretinoin therapy: use in a patient with multiple cutaneous squamous cell carcinomas and keratoacanthomas
218. Gram negative folliculitis — a complication of antibiotic therapy in acne vulgaris
219. Prolonged reduction of Propionibacterium acnes in acne conglobata patients treated with 13-cis-retinoic acid
220. Multiple bowenoide Arsenkeratosen
221. Elevated CPK and isotretinoin. Correspondence
222. Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells
223. Effects of etretinate on Darier’s disease
224. Kombinierte Retinoid und UV-Phototherapie bei Pustulosis subcornealis (Sneddon-Wilkinson)
225. Morbus Reiter: Erfolgreiche Kombinations-Chemotherapie mit Methotrexat, Etretinat und Prednisolon
226. Keratosis palmoplantaris areata Siemens: Therapieversuch mit aromatischem Retinoid Ro 10-9359
227. Oral aromatic retinoid (Ro 10-9359) treatment of two patients suffering with the severe form of epidermodysplasia verruciformis
228. Use of isotretinoin in severe cases with papular pustular acne
229. Etretinat bei Psoriasis
230. Retinoids in oncology
231. Oral treatment of keratinising disorders of skin and mucous membranes with etretinate
232. Haarwachstum, Leberwerte und Lichtempfindlichkeit unter oraler Retinoid-Therapie bei Psoriasis
233. Chemotherapie kutaner T-Zell-Lymphome mit Arotinoid
234. Zur systemischen Behandlung des oralen Lichen ruber planus mit einem aromatischen Retinoid (Ro 10-9359)
235. Response of multiple syringomas to isotretinoin
236. Uranitis circinata bei Morbus Reiter. Therapie mit Etretinat (Tigason®)
237. Severe disorders of keratinization: effects of treatment with Tigason® (etretinate)
238. Low-dose 13-cis-retinoic acid and cyproterone acetate in acne
239. Response of rosacea to isotretinoin
240. Effects of isotretinoin on serum lipids and lipoproteins, liver and thyroid function
241. Vergleich von Re-PUVA und aromatischem Retinoid Ro 10-9359 mit Methotrexat bei schweren Psoriasisformen
242. Retinoids: a new class of compounds with prophylactic and therapeutic activities in oncology and dermatology
243. Thalidomide and congenital abnormalities
244. Orale Behandlung der Acne conglobata mit 13-cis-Retinsäure: Ergebnisse der deutschen multizentrischen Studie nach 24 wöchiger Behandlung
245. Activity of isotretinoin against squamous cell cancers and preneoplastic lesions
246. Antiacne activity of retinoids in the rhino mouse
247. The influence of Tigason® (Ro 10-9359) on the serum lipoproteins in men
248. Premature epiphyseal closure in a child receiving oral 13-cis-retinoic acid
249. 13-Cis-retinoic acid in mycosis fungoides
250. Treatment of systematized verrucous epidermal naevus by aromatic retinoid (Ro 10-9359)
251. Etretinate in treatment of actinic keratosis: a double-blind crossover study
252. Treatment of acanthosis nigricans with etretinate in a patient with Lawrence-Seip syndrome (generalized lipodystrophy)
253. Isotretinoin versus etretinate therapy in generalized pustular and chronic psoriasis
254. Behandeling van patienten met multiple basale-cellencarcinomen met een aromatisch retinoid (Tigason®)
255. Gram negative Follikulitis — Verlaufsbeobachtungen und therapeutische Möglichkeiten
256. The biochemistry and pathology of hypervitaminosis A
257. Orale Behandlung der Roszea mit 13-cis-Retinsäure
258. In-vivo-Test zum Nachweis der antiinflammatorischen Wirkung der 13-cis-Retinsäure
259. Ro 11-1430, a new retinoic acid derivative for the topical treatment of acne
260. 13-Cis-retinoic acid has major anti-inflammatory activity in vivo. Abstract
261. Chromosomal analysis in patients treated with the aromatic retinoid Ro 10-9359
262. Oral retinoids — present status
263. Oral retinoids in psoriasis: current clinical experiences and possible mechanism of action
264. Teratogenität von Isotretinoin
265. Retinoids in clinical dermatology: an update
266. Evidence for anti-inflammatory activities of oral synthetic retinoids: experimental findings and clinical experience
267. Orale Psoriasis-Therapie mit einem neuen aromatischen Retinoid
268. Traitément du psoriasis pustuleux par un nouveaux rétinoide aromatique (Ro 10 9359)
269. Oral treatment of keratosis follicularis with a new aromatic retinoid
270. Retinoid-PUVA (Re-PUVA): Systemische Kombinations-Behandlung bei Psoriasis
271. Systemic use of a new retinoid with and without local dithranol treatment in generalized psoriasis
272. Tissue changes in psoriatic plaques after oral administration of retinoids
273. Current developments of oral retinoid therapy with three generations of drugs
274. Oral retinoid and UVB radiation: a new alternative treatment for psoriasis on an outpatient basis
275. Isotretinoin and oral contraceptive steroids
276. Nevoid hyperkeratosis of the nipple and areola mammae: ineffectiveness of etretinate therapy
277. Behandlung der Psoriasis mit einem oral wirksamen aromatischen Retinoid
278. Traitment oral des formes graves de psoriasis par un analogue de la vitamin A acide
279. Pilot study of a new retinoid, Ro 12-7554, in psoriasis and in some congenital disorders of keratinization
280. Keratosis lichenoides chronica
281. Topical Ro 11-1430 (motretinid) treatment of acne vulgaris
282. Pharmacokinetics and metabolism of oral aromatic retinoids
283. Etretinate and isotretinoin, two retinoids with different pharmacokinetic profiles
284. Effects of etretinate on epidermal cell production and metabolism in normal skin
285. Acrodermatitis continua Hallopeau: treatment with etretinate and review of relapsing pustular eruptions of the hands and feet
286. Comparative analysis of two retinoids in the treatment of disorders of keratinization
287. Treatment of basal cell carcinomas with 13-cis-retinoic acid
288. Isotretinoin versus placebo in the treatment of cystic acne
289. Treatment of lamellar ichthyosis and other keratinising disorders with an oral synthetic retinoid
290. Treatment of Darier’s disease, lamellar ichthyosis, pityriasis rubra pilaris, cystic acne and basal cell carcinoma with oral 13-cis-retinoic acid
291. Treatment with an oral aromatic retinoid in linear porokeratosis
292. Oral retinoid for psoriasis — a report of a double-blind study
293. Effects of neutrophil chemotaxis in cystic acne
294. Skeletal toxicity associated with long term administration of 13-cis-retinoic acid for refractory ichthyosis
295. Der Einfluβ des aromatischen Retinoids Ro 10-9359 und der 13-cis-Retinsäure Ro 4-3780 auf die Talgdrüsen des Syrischen Hamsters
296. Autoradiographische Untersuchungen an Epidermis und Adnexen nach Vitamin A-Säure-Behandlung
297. Isotretinoin zur örtlichen Behandlung von Akne und Rosazea sowie tierexperimentelle Untersuchungen mit Isotretinoin und Arotinoid
298. 13-cis-Retinsäure zur oralen Behandlung der Acne conglobata. Ergebnisse einer multizentrischen Studie
299. Action of 13-cis-retinoic acid (isotretinoin) in acne, rosacea and gram negative folliculitis
300. Anti-inflammatory effects of 13-cis-retinoic acid
301. Orale Behandlung schwerster Akneformen mit 13-cis-Retinsäure. Klinische Ergebnisse
302. Effect of topical application of 13-cis-retinoic acid on skin of hairless rats and hairless mice
303. Die Proliferationskinetik normaler Epidermis vor und nach äusserlicher Anwendung einer 1% igen Vitamin A-Säure-Lösung
304. Effect of etretinate on the distribution of Langerhans cells and T-lymphocytes in psoriatic skin
305. Pharmacokinetics of an aromatic retinoid (Ro 10-9359) and its metabolites Ro 10-1670 and Ro 13-7652 in patients with Darier’s disease
306. Vitamin A acid in the local treatment of congenital ichthyosiform erythrodermia
307. Two years experience with Tigason treatment of pustulosis palmo-plantaris and eczema keratoticum manuum
308. Retinoids as regulators of macrophage function
309. Pemphigus herpetiformis. Abstract
310. Etretinate: management of keratoma hereditaria mutilans in four family members
311. A malignant eccrine poroma responds to isotretinoin (13-cis-retinoid acid)
312. Retinoids: effects on the liver
313. Oral isotretinoin therapy followed by psoralens and ultraviolet A or ultraviolet B for psoriasis
314. Retinoid concentrations in skin, serum and adipose tissue of patients treated with etretinate
315. Etretinate in the treatment of dystrophic changes of the vulva — an open study. Abstract
316. Paquioniquia congenita-tratada con retinoide par via oral
317. Ro 10-9359: an aromatic retinoid in the treatment of psoriatic arthritis: clinical and immunological studies
318. Short-term etretinate for pustular psoriasis
319. Skeletal deformities following chronic hypervitaminosis
320. Retinoids in keratinizing diseases and acne
321. Perorale Applikation zweier Derivate der Vitamin A-Säure zur internen Psoriasis-Therapie (13-cis-beta Vitamin A-Säure und Vitamin A-Säure-Äthylamid)
322. Erste Erfahrungen mit dem Vitamin-A-Säure-Derivat Ro 10-9359 bei Virusepitheliomen
323. Trial of an aromatic retinoid in patients with solid tumours
324. Treatment of cutaneous lupus erythematodes with etretinate
325. Effects of 13-cis-retinoids on premalignant and malignant cells of lung origin
326. Meleda-disease-Akroerythrokeratoderma
327. Behandlung des Lichen ruber mucosae mit Vitamin-A-Säure-Derivaten
328. Die Lokaltherapie der Akne vulgaris mit einem aromatischen Retinoid
329. Aromatic retinoid and 13-cis-retinoic acid: spermatological investigations
330. Zur systemischen Anwendung eines aromatischen Vitamin A-Säure Derivates (Ro 10-9359) bei Psoriasis und Ker atosen
331. Resolution of disseminated granuloma anulare following isotretinoin therapy
332. Haut-Lipide während 13-cis-Retinoid-Therapie bei Akne
333. Essai de prévention des épithéliomas cutanés par le rétinoide aromatique
334. Light and electron microscopic changes of human epidermis with oral retinoid treatment
335. Vitamin A-Säure bei Hyperkeratosen, cpithclialcn Tumoren und Akne
336. The efficacy of a new retinoid (Ro 10-9359) in lichen planus
337. Steatocystoma multiplex suppurativum: treatment with isotretinoin
338. Isoaccapting serine t-RNA’s pattern as marker of epidermal differentiation: its alteration under retinoids
339. Isotretinoin treatment of acne and related disorders: an update
340. Topical tretinoin therapy and oral lichen planus
341. A serious side-effect of etretinate
342. Eruptive keratoacanthoma with an internal malignant neoplasm
343. Zur Therapie verschiedener Dermatosen (ausschlieβlich Psoriasis) mit Tigason®
344. Effect of systemic Ro 10-9359 treatment on immunological parameters in Darier’s disease
345. Oral isotretinoin therapy for familial Muir-Torre syndrome
346. Activity of vitamin A analogues in cell cultures of mouse epidermis and organ cultures of hamster trachea
347. Chemoprevention of cancer with retinoids
348. Erythema annulare centrifugum mit Pustulation. Erfolgreiche Retinoidtherapie
349. Effect of a new retinoid, arotinoid (Ro 13-6298), on in vitro keratinocyte proliferation and differentiation
350. Changes in keratin polypeptides profiles of human normal and psoriatic epidermis with systemic aromatic retinoid therapy. Abstract
351. Keratin polypeptide profile in psoriatic epidermis normalized by treatment with etretinate (aromatic retinoid Ro 10-9359)
352. The treatment of steatocystoma multiplex suppurativum with isotretinoin. Correspondence
353. Retinoid-SUP-Therapie der Psoriasis
354. Pemphigus vegetans (Hallopeau) mit eosinophiler Spongiose — erfolgreiche Retinoidtherapie
355. Eruptive Keratoakanthome
356. Effect of oral 13-cis-retinoic acid at three dose levels on sustainable rates of sebum secretion and on acne
357. Successful treatment of hidradenitis sup-purativa with etretinate
358. Atrophy induced in the tubules of the testes of Syrian hamsters by two retinoids
359. Clinical observations on oral retinoid therapy of psoriatic arthropathy (Ro 10-9359)
360. Isotretinoin therapy for acne: results of a multicenter dose-response study
361. Changes in long term sebum production with 13-cis-retinoic acid on skin surface lipid composition
362. Zur Persönlichkeit und zu seelischen Folgen einer 13-cis-Retinsäure-Therapie
363. Zur Lokalbehandlung von Keratosen mit Vitamin A-Säure
364. The therapeutic use of vitamin A acid
365. Oralte Behandlung mit Vitamin-A-Säure-Derivaten bei Hauterkrankungen
366. Oral retinoid (Ro 10-9359) in children with lamellar ichthyosis, epidermolytic hyperkeratosis and symmetrical progressive erythrokeratoderma
367. Pharmacokinetic studies of etretinate in rats: blood level profiles and tissue distribution and urinary, faecal and biliary excretion
368. Wirkungsmechnismen und Nebenwirkungen der Retinoide
369. Vorläufige Ergebnisse der Re-PUVA-Therapie bei kutanem T-Zell-Lymphom
370. Pachyonychia congenita
371. Treatment of palmoplantar pustulosis with Tigason
372. Spermatological examinations in males treated with etretinate
373. Topical treatment of keratosis palmaris et plantaris with tretinoin
374. Effekte von oralem Arotinoidethylester auf die Talgdrüsen des syrischen Hamsters
375. Reversible Spermatogenese-Störung durch aromatisches Retinoid bei Meerschweinchen
376. Epidermal changes induced by oral excess of aromatic retinoid in guinea pigs
377. Ultrastructural evidence suggesting an immunomodulatory activity of oral retinoid
378. Arotinoid: a new potent oral retinoid: preliminary results
379. Antipsoriatic activity of a new synthetic retinoid: the arotinoid Ro 13-6298
380. Effects of retinoids on chondrogenesis and epidermatogenesis in vitro
381. Combination therapy for psoriasis with methotrexate and etretinate
382. 3H-TdR autoradiogram in the skin of guinea pigs after topical application of aromatic retinoid (Ro 10-9359)
383. Therapeutische Erfolge mit aromatischem Retinoid (Tigason®) bei Sharp-Syndrom und progressiver Sklerodermie
384. Trimethylpsoralen bath plus ultraviolet A combined with oral retinoid (etretinate) in the treatment of severe psoriasis
385. Retinol-binding proteins and the plasma transport of etretinate (Ro 10-9359) in man
386. Dose-response relationship in isotretinoin therapy for conglobate acne
387. Combined treatment of psoriasis with a new aromatic retinoid (Tigason®) in low dosage orally and triamcinolone actonide cream topically: a double-blind trial
388. Methotrexate and etretinate as concurrent therapies in severe psoriasis
389. Identification of 4-oxo-13-cis-retinoic acid as the major metabolite of 13-cis-retinoid acid in human blood
390. In vitro metabolism of 13-cis-retinoic acid by 9000 xg rat liver supernatant
391. Basal cell naevus syndrome: immune status, etretinate therapy and etretinate hepatitis
392. Etretinate (Tigason®) hepatitis in 2 patients
393. Trichoepithelioma, cystic acne and 13-cis-retinoid acid
394. Oral retinoids and psoriasis
395. Benign intracranial hypertension during etretinate therapy for mycosis fungoides
396. Orale 13-cis-Retinsäure Therapie bei Adenoma sebaceum symmetricum und schwersten Akne- und Rosazeaformen
397. 13-cis-Retinsäure und Spermatogenese
398. 13-cis-Retinsäure. Pharmakologische und toxikologische Untersuchungen bei der Behandlung schwerster Akneformen
399. Treatment of cutaneous sarcoidosis with isotretinoin
400. Studies of serum level and albumin binding capacities of all-trans- and 13-cis-retinoic acid. Abstract
401. A case of mycosis fungoides treated with etretinate
402. Isotretinoin in cutaneous T-cell lymphoma
403. Papillon-Lefèvre-Syndrom. Behandlung mit Etretinat
404. Pemphigus herpetiformis
405. Effect of systemic retinoids (isotretinoin and etretinate) on PUVA-induced carcinogenesis in albino hairless mice
406. Reduction of bacterial skin flora during oral treatment of severe acne with 13-cis-retinoic acid
407. Neue Möglichkeiten der ambulanten Behandlung der Psoriasis vulgaris: Erfahrungen mit einem aromatischen Retinoid in Kombination mit der Photochemotherapie
408. Mutilation palmoplantar keratoderma successfully treated with etretinate
409. The use of isotretinoin in disorders of keratinization
410. General clinical toxicology of oral retinoids
411. Etretinate therapy in generalized pustular psoriasis (Zumbusch type)
412. The effect of etretinate on cyclo-oxygenase and lipoxygenase products of arachidonic acid in psoriatic skin
413. The use of etretinate in psoriatic arthropathy. Correspondence
414. Systemic isotretinoin treatment of oral and cutaneous lichen planus
415. A case of eruptive keratoacanthoma treated by oral etretinate
416. Anti-oxidant effects of retinoids on inflammatory skin disease