Comparison of the molecular structure of GABA/benzodiazepine receptors purified from rat and human cerebellum

Molecular Brain Research

Volumn 2, Issue 3, 1987, Pages 223-233

  Sweetnam, Paul ^a   Nestler, Eric ^a   Gallombardo, Peter ^a   Brown, Serena ^a   Duman, Ron ^a   Bracha, H Stefon ^b   Tallman, John ^a  

^a YALE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Affinity chromatography; Cerebellum; GABA benzodiazepine receptor; Glycosylation; Monoclonal antibody; Photolabeling

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; BENZODIAZEPINE; MONOCLONAL ANTIBODY; 4 AMINOBUTYRIC ACID A RECEPTOR; GLYCOSIDASE; PEPTIDE HYDROLASE;

AFFINITY CHROMATOGRAPHY; BRAIN; CENTRAL NERVOUS SYSTEM; CHEMICAL STRUCTURE; CLINICAL ARTICLE; DIAGNOSIS; DRUG RECEPTOR BINDING; HUMAN; RAT; ANIMAL; ARTICLE; CEREBELLUM; COMPARATIVE STUDY; CONFORMATION; ISOLATION AND PURIFICATION; MALE; MOLECULAR WEIGHT; RAT STRAIN; SPECIES DIFFERENCE;

ANIMALS; CEREBELLUM; GLYCOSIDE HYDROLASES; HUMANS; MALE; MOLECULAR CONFORMATION; MOLECULAR WEIGHT; PEPTIDE HYDROLASES; RATS; RATS, INBRED STRAINS; RECEPTORS, GABA-A; SPECIES SPECIFICITY;

EID: 0023191864     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0169-328X(87)90029-5     Document Type: Article

References (29)

1. Two-dimensional gel electrophoresis of membrane proteins
2. A receptor oligomer
3. Molecular biology of inhibitory amino acid receptors
4. Monoclonal antibodies modulate binding to the GABA/benzodiazepine receptor
5. 3H-DOPA in various regions of the brain
6. A/benzodiazepine receptors in different brain areas
7. Qualitative variation of photolabeled benzodiazepine receptors in different species
8. Proteolytic degradation of neuronal benzodiazepine binding sites
9. Cleavage of structural proteins during the assembly of the head bacteriophage T4
10. A synthetic non-benzodiazepine receptors: a probe for investigating neuronal substrates of anxiety
11. Benzodiazepine receptor protein identified and visualized in rat brain tissue by a photoaffinity label
12. High resolution two-dimensional electrophoresis of proteins
13. Polyclonal antibodies developed against rat GABA-benzodiazepine receptor
14. A GABA/benzodiazepine receptor complex from bovine brain: purification, reconstitution and immunological characterization
15. Molecular heterogeneity of benzodiazepine receptors
16. Properties of flunitrazepam binding to different benzodiazepine binding proteins
17. A gamma-aminobutyric acid/benzodiazepine complex of bovine cerebral cortex
18. A gamma-aminobutyric acid-benzodiazepine complex from bovine cerebral cortex: improved purification with the preservation of the regulatory sites and their interactions
19. Molecular aspects of benzodiazepine receptor function
20. Regional differences in brain benzodiazepine receptor carbohydrates
21. Structural homology of Torpedo californica acetylcholine receptor subunits
22. Characterization of photolabeled benzodiazepine receptors
23. Modulation of benzodiazepine binding site sensitivity
24. Receptors for the age of anxiety: pharmacology of the benzodiazepines
25. GABAergic modulation of benzodiazepine binding site sensitivity
26. Characterization of photoaffinity labeling of benzodiazepine binding sites
27. Photoaffinity labeling of benzodiazepine receptors causes altered agonist—antagonist interaction
28. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications