Altered metabolic properties of cultured skin fibroblasts in Alzheimer's disease

Annals of Neurology

Volumn 21, Issue 5, 1987, Pages 451-457

  Sims, Neil R ^a   Finegan, Janet M ^a   Blass, John P ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RADIOISOTOPE;

ALZHEIMER DISEASE; CELL CULTURE; CENTRAL NERVOUS SYSTEM; DIAGNOSIS; FIBROBLAST; GLUTAMINE C 14; HUMAN; HUMAN CELL; IN VITRO STUDY; METABOLISM; PRIORITY JOURNAL;

ALZHEIMER DISEASE; BLOOD GLUCOSE; CARBON DIOXIDE; CELLS, CULTURED; ENERGY METABOLISM; FIBROBLASTS; HUMAN; LACTATES; LACTIC ACID; OXYGEN CONSUMPTION; SKIN; SUPPORT, NON-U.S. GOV'T;

EID: 0023191781     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.410210507     Document Type: Article

References (48)

1. Alzheimer's disease: further evidence of a microtubular defect
2. A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and Alzheimer's disease
3. An examination of the efficiency of glucose and glutamine as energy sources for cultured chick pigment epithelial cells
4. 18F scan in Alzheimer and multi‐infarct dementia
5. Alzheimer's disease: a metabolic systems degeneration?
6. Familial Alzheimer dementia: a prevalent disorder with specific clinical features
7. The development of the pathological changes of Alzheimer's disease and senile dementia in patients with Down's syndrome
8. A possible role of zinc in the pathology of dementia
9. Regional cortical dysfunction in Alzheimer's disease as determined by positron emission tomography
10. Studies in aging of the brain: IV. Familial Alzheimer disease: relation to transmissible dementia, aneuploidy and microtubular defects
11. Alzheimer's disease: a disorder of cortical cholinergic innervation
12. Aluminum, neurofibrillary degeneration and Alzheimer's disease
13. Respiration and glycolysis in the human diploid cell strain WI‐38
14. 18F‐2‐deoxy‐2‐fluoro‐D‐glucose as a tracer in positron emission tomographic study of senile dementia
15. Regional cerebral oxygen supply and utilization in dementia. A clinical and physiological study with oxygen‐15 and positron tomography
16. Evidence for and against the transmissibility of Alzheimer's disease
17. Familial Alzheimer's disease in two kindreds of the same geographic origin
18. Skin fibroblast microtubular network in Alzheimer disease
19. Asymmetry of brain metabolism and cognitive function
20. Alzheimer's disease: genetic aspects and associated clinical disorders
21. Insulin stimulation of glucose entry in cultured human fibroblasts
22. Immunological dysfunction in Alzheimer's disease
23. Differences in lateral hemispheric asymmetries of glucose utilization between early‐ and late‐onset Alzheimer‐type dementia
24. Senile dementia—A clinical, sociomedical and genetic study
25. Protein measurement with the Folin phenol reagent
26. Biochemistry of Alzheimer's dementia
27. Abnormal erythrocyte choline and influx in Alzheimer's disease
28. Fibroblasts as an experimental tool in metabolic and hormone studies. I. Growth and glucose metabolism of fibroblasts in culture
29. Neuronotrophic factors and Alzheimer's disease
30. Detection of primary antimitochondrial activity of drugs in cultured mammalian cells utilizing glutamine as the carbon source
31. Alzheimer's disease: X‐ray spectrometric evidence of aluminum accumulation in neurofibrillary tangle‐bearing neurons
32. Altered calcium uptake in cultured skin fibroblasts from patients with Alzheimer's disease
33. Alterations in calcium content and biochemical processes in cultured skin fibroblasts from aged and Alzheimer donors
34. On prions causing dementia: Molecular studies of the scrapie agent
35. Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells
36. 133Xe inhalation: methodology and applications in neuropsychology and psychiatry
37. Radiosensitivity in Alzheimer disease and Parkinson disease
38. Relationship between plaques, tangle and dementia in Down's syndrome
39. 14C]glucose by tissue prisms from human neocortex
40. 14C]glucose in vitro in human neocortex
41. Altered glucose metabolism in fibroblasts from patients with Alzheimer's disease
42. Mitochondrial function in Alzheimer's disease measured in vitro using neocortical tissue homogenates
43. Cerebral circulatory and metabolic changes associated with aging
44. Senile dementia of the Alzheimer type: defining a disease
45. Senile dementia of the Alzheimer type: possibility of infectious etiology in genetically susceptible individuals
46. Growth of human diploid fibroblasts in the absence of glucose utilization
47. Cell membrane abnormality in Alzheimer's disease