Pharmacokinetically guided dose escalation in phase I clinical trials. Commentary and proposed guidelines

European Journal of Cancer and Clinical Oncology

Volumn 23, Issue 7, 1987, Pages 1083-1087

[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; DRUG ADMINISTRATION SCHEDULE; DRUG EVALUATION; HUMAN; KINETICS; NEOPLASMS;

EID: 0023184783     PISSN: 02775379     EISSN: None     Source Type: Journal    
DOI: 10.1016/0277-5379(87)90365-8     Document Type: Article

References (3)

1. EORTC guidelines for phase I trials with single agents in adults
2. Relation of preclinical toxicology to findings in early clinical trials
3. Potential roles for preclinical pharmacology in phase I clinical trials