Crosslinkage of B lymphocyte surface immunoglobulin by anti-Ig or antigen induces prolonged oscillation of intracellular ionized calcium

Journal of Experimental Medicine

Volumn 166, Issue 2, 1987, Pages 601-606

  Alexander Wilson, H ^a   Greenblatt, David ^a   Poenie, Martin ^b   Finkelman, Fred D ^c   Tsien, Roger Y ^b  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; IMMUNOGLOBULIN; IMMUNOGLOBULIN ANTIBODY; MEMBRANE ANTIGEN;

ANIMAL CELL; B LYMPHOCYTE; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CELL LINE; IN VITRO STUDY; LYMPHATIC SYSTEM; MOUSE; NONHUMAN; PRELIMINARY COMMUNICATION; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIGENS; CALCIUM; MICE; MICE, INBRED BALB C; RECEPTORS, ANTIGEN, B-CELL;

EID: 0023178662     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.166.2.601     Document Type: Article

References (16)

1. Bijsterbosch, M. K., C. J. Meade, G. A. Turner, and G. G. B. Klaus. B lymphocyte receptors and polyphosphoinositide degradation. Cell. 41: 999.
2. Nishizuka, Y. 1984. The role of protein kinase C in cell surface signal transduction and tumor promotion. Nature (Load.). 308: 693.
3. Downes, C. P., and R. H. Michell. 1985. Molecular Mechanisms of Transmembrane Signaling. P. Cohen and D. Houslay, editors. Elsevier Science Publishing Co., Inc., New York. 3-56.
4. Wilson, H. A., D. Greenblatt, C. W. Taylor, J. W. Putney, R. Y. Tsien, F. D. Finkelman, and T. M. Chused. 1987. The B lymphocyte calcium response to anti-Ig is diminished by membrane immunoglobulin cross-linkage to the Fc receptor. J. Immunol. 138: 1712.
5. Poenie, M., J. Alderton, R. Steinhardt, and R. Y. Tsien. 1986. Calcium rises abruptly and briefly throughout the cell at the onset of anaphase. Science (Wash. DC). 233: 886.
6. Howard, M., J. Faraf, M. Hilfiker, B. Johnson, K. Takatsu, T. Hamaoka, and W. E. Paul. 1982. Identification of a T cell-derived B cell growth factor distinct from IL-2. J. Exp. Med. 155: 914.
7. Leibson, H. J., P. Marrack, and J. W. Kappler. 1981. B cell helper factors: Requirement for both interleukin 2 and another 40,000 mol wt factor. J. Exp. Med. 154: 1681.
8. Mosier, D. E. 1981. Primary in vitro antibody responses by purified murine B lymphocytes in serum-free defined medium. J. Immunol. 127: 1490.
9. Stein, P., P. Dubois, D. Greenblatt, and M. Howard. 1986. Induction of antigenspecific proliferation in affinity purified small B lymphocytes: Requirement for BSF-1 by type 2 but not type 1 thymus independent antigens. J. Immunol. 136: 2080.
10. Finkelman, F. D., S. W. Kessler, J. F. Mushinski, and M. Potter. 1981. IgD-secreting murine plasmacytomas: Identification and partial characterization of two IgD myeloma proteins. J. Immunol. 126: 680.
11. Goroff, D. K., A. Stall, J. J. Mond, and F. D. Finkelman. 1986. In vitro and in vivo B lymphocyte activating properties of monoclonal anti-6 antibodies. I. Determinants of B lymphocyte activating properties. J. Immunol. 136: 2382.
12. Grynkiewicz, G., M. Poenie, and R. Y. Tsien. 1985. A new generation of Ca21 indicators with greatly improved fluorescence properties. J. Biol. Chem. 260: 3440.
13. Tsien, R. Y., and M. Poenie. 1986. Fluorescence ratio imaging: A new window into intracellular ionic signalling. Trends Biochem. Sci. 11: 450.
14. Mizuguchi, J., M. A. Beaven, J. Hu Li, and W. E. Paul. 1986. Phorbol myristate acetate inhibits anti-IgM-mediated signaling in resting B cells. Proc. Natl. Acad. Sci. USA. 83: 4474.
15. Bijsterbosch, M. K., and G. G. B. Klaus. 1985. Crosslinking of surface immunoglobulin and Fc receptors on B lymphocytes inhibits stimulation of inositol phospholipid breakdown via the antigen receptors. J. Exp. Med. 162: 1825.
16. Woods, N. M., K. S. R. Cuthbertson, and P. H. Cobbold. 1986. Repetitive transient rises in cytoplasmic free calcium in hormone-stimulated hepatocytes. Nature (Loud.). 319: 600.