Effect of -∆9-tetrahydrocannabinol on the in vitro uptake of α-amino isobutyric acid by term human placental slices

Pediatric Research

Volumn 21, Issue 1, 1987, Pages 104-107

  Fisher, Stanley E ^a   Atkinson, Mark ^a   Chang, Benedict ^a  

^a NORTH SHORE UNIVERSITY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 2 METHYLPROPIONIC ACID; 2 AMINO 2 METHYLPROPIONIC ACID C 14; DRONABINOL; RADIOISOTOPE; TETRAHYDROCANNABINOL; UNCLASSIFIED DRUG;

DRUG ACCUMULATION; DRUG EFFICACY; FEMALE GENITAL SYSTEM; FETUS; HUMAN; HUMAN CELL; INTRAUTERINE GROWTH RETARDATION; NORMAL HUMAN; PHARMACOKINETICS; PLACENTA; PLACENTAL TRANSFER; PREGNANCY; PRIORITY JOURNAL;

AMINOISOBUTYRIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMAN; IN VITRO; KINETICS; MICROSCOPY, ELECTRON; PLACENTA; SUPPORT, U.S. GOV'T, P.H.S.; TETRAHYDROCANNABINOL; TIME FACTORS;

EID: 0023130696     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1203/00006450-198701000-00022     Document Type: Article

References (34)

1. Idanpaan-Hcikkila J, Fritchie GE, Englert LF, Ho BT, Mclsaac WM 1969 Placental transfer of 3H-l-delta-9-tetrahydro-cannabinol. N Engl J Med 281:330
2. Martin BR, Dewey WL, Harris LS, Beckner JS 1977 5-delta-9-tetrahydrocannabinol distribution in pregnant dogs and their fetuses. Res Commun Chem Pathol Pharmacol 17:457-470
3. Banchereau J, Desoize B, Leger C, Nahas G 1979 Inhibitory effects of delta-9-tetrahydrocannabinol and other psychotropic drugs on cultured lymphocytes. In: Nahas G, Paton W (eds) Marijuana: Biological Effects. Pergamon Press. New York, pp 129-144
4. Hecht F, Beas R, Lees N, Jolly H, Roberts P 1968 Lysergic acid diethylamide and cannabis as possible teratogens in man. Lancet 2:1087
5. Qazi QH, Mariano E, Beller E, Milman D, Crombleholme W 1982 Is marihuana smoking fetotoxic? Pediatr Res I6:272A
6. Abel EL 1983 Marihuana, Tobacco. Alcohol and Reproduction. CRC Press, Boca Raton, pp 31-33
7. Hingson R, Alpert JJ, Day N, Dooling E, Kanye H, Morelock S, Oppenheimer E. Zuckerman B 1982 Effect of maternal drinking and marijuana use on fetal growth and development. Pediatrics 70:539-546
8. Miller RK, Berndt WD 1975 Mechanisms of transport across the placenta: an in vitro approach. Life Sci 16:7-30
9. Henderson GL 1982 Maternal ethanol consumption and fetal development: two potential mechanisms. Dev Pharmacol Ther 4 suppl l:66-78
10. Fisher SE, Atkinson M, Burnap JK, Jacobson S, Sehgal PK, Scott W, Van Thiel DH 1982 Ethanol-associated selective fetal malnutrition: a contributing factor in the fetal alcohol syndrome. Alcoholism (NY) 6:197-201
11. Fisher SE, Atkinson M, Van Thiel DH, Rosenblum E, David R, Holzman I 1981 Selective fetal malnutrition: the effect of ethanol and acetaldehyde upon in vitro uptake of alpha amino isobutyric acid by human placenta. Life Sci 29:1283-1288
12. Akedo H, Christensen HN 1962 Nature of insulin action on amino acid uptake by the isolated diaphragm. J Biol Chem 237:118-122
13. Segel II I 1975 Biochemical Calculations. John Wiley and Sons. New York, pp 246-273
14. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ 1951 Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
15. Nahas GG 1979 Current status of marujuana research. JAMA 242:2775-2778
16. Dvilansky A, Zolotov Z, Herzliker B, Nathan I 1984 Effects of ethanol, CBD and delta-1-THC on proliferation of K-562 cells. Int J Tissue Reac 6:409-412
17. Desoize B, Leger C, Nahas G 1979 Plasma membrane inhibition of macro-molecular precursor transport by THC. Biochem Pharmacol 28:113-118
18. Jering H, Toro-Goyco E 1979 Effect of (“)-delta-9-tetrahydrocannabinol on nucleoside and amino acid uptake in reuber-H-35 hepatoma cells. Mol Pharmacol 15:627-632
19. Nahas GG, Morishima A, Desoize 1977 Effects of cannabinoids on macromolecular synthesis and replication of cultured lymphocytes. Fed Proc 36:1748-1752
20. Lemberger L, Tamarkin NR, Axelrod J, Kopin IJ 1971 Delta-9-tetrahydrocannabinol: metabolism and disposition in long term marhuana smokers. Science 173:72-74
21. Kreuz DS, Axelrod J 1973 Delta-9-tetrahydrocannabinol: localization in body fat. Science 179:391-393
22. Hunt A, Jones RT 1980 Tolerance and disposition of tetrahydrocannabinol in man. J Pharmacol Exp Ther 215:35-44
23. Leuschner JTA, Wing DR, Harvey DJ, Brent GA, Dempsey CE, Watts A, Paton WDW 1984 The partitioning of delta-1-tetrahydrocannabinol into erythrocyte membranes in vivo and its effect on membrane fluidity. Exper-ientia 40:866-868
24. Harbison RD, Mantilla-Plata B 1972 Perinatal toxicity, maternal distribution and placental transfer of tetrahydrocannabinol. J Pharmacol Exp Ther 140:446-453
25. Fisher SE, Atkinson M, Jacobson S, Sehgal P, Burnap J, Holmes E, Teichberg S, Kahn E, Jaffe R, Van Thiel DH 1983 Selective fetal malnutrition: The effet of in vivo ethanol exposure upon in vitro placental uptake of amino acids in the non-human primate. Pediatr Res 17:704-707
26. Lin GWJ 1981 Effect of ethanol feeding during pregnancy on placental transfer of alpha amino isobutyric acid in the rat. Life Sci 28:595-601
27. Henderson GI, Patwardhan RV, McLeroy S, Schenker S 1982 Inhibition of placental amino acid uptake in rats following acute and chronic ethanol exposure. Alcoholism (NY) 6:495-505
28. Roth SH, Williams PJ 1979 The non-specific membrane binding properties of delta-9-tetrahydrocannabinol and the effects of various solubilizers. J Pharm Pharmacol 31:224-230
29. McCallum NK, Eastwood ME 1978 In vivo binding of delta-1-tetra-hydrocannabinol and cannabinol to rat serum proteins. J Pharm Pharmacol 30:384-386
30. Husain S, Lame MW 1981 Inhibitory effects of delta-9-tetra-hydrocannabinol on glycolytic substrate in rat testis. Pharmacol 23:102-112
31. Laurent B, Roy PE, Gailis 1974 Inhibition by delta-1-tetrahydro-cannabinol of a Na+-K+ transport ATPase from rat ileum. Preliminary report. Can J Physiol Pharmacol 52:1110-1113
32. Toro-Goyco E, Rodriguez MB, Preston AM 1978 On the action of delta-9-tetrahydrocannabinol as an inhibitor of sodium and potassium-dependent adenosine triphosphatase. Mol Pharmacol 14:130-137
33. Bloom AS, Haavik CO, Strehlow D 1978 Effects of delta-9-tetra-hydrocannabinol on ATPases in mouse brain subcellular fractions. Life Sci 23:1399-1404
34. Martin BR 1986 Cellular effects of cannabinoids. Pharmacol Rev 38:45-74