Moderate sodium restriction with angiotensin converting enzyme inhibitor in essential hypertension: A double blind study

British Medical Journal (Clinical research ed.)

Volumn 294, Issue 6571, 1987, Pages 531-534

  MacGregor, Graham A ^a   Markandu, Nirmala D ^a   Jsinger, Donald R ^a   Cappuccio, Francesco P ^a   Shore, Angela C ^a   Sagnella, Giuseppe A ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; SLOW SODIUM; SODIUM; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

CARDIOVASCULAR SYSTEM; CLINICAL ARTICLE; DIET THERAPY; DRUG EFFICACY; DRUG THERAPY; ESSENTIAL HYPERTENSION; HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; THERAPY;

CAPTOPRIL; CLINICAL TRIALS; COMBINED MODALITY THERAPY; DIET, SODIUM-RESTRICTED; DOUBLE-BLIND METHOD; HUMANS; HYPERTENSION; RANDOM ALLOCATION; SODIUM;

EID: 0023093815     PISSN: 02670623     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.294.6571.531     Document Type: Article

References (19)

1. Brown, J.J., Lever, A.F., Robertson, J.I.S., Semple, P.F., Should dietary sodium be reduced? The sceptics' position. Q J Med 1984;212:427-37.
2. MacGregor, G.A., Sodium is more important than calcium in essential hypertension. Hypertension 1985;7:628-37.
3. Longworth, D.L., Drayer, J.I.M., Lieber, M.A., Laragh, J.H., Divergent blood pressure responses during short-term sodium restriction in hypertension. Clin Pharmacol Ther 1980;27:544-6.
4. MacGregor, G.A., Markandu, N.D., Sagnella, G.A., Dietary sodium restriction in normotensive subjects and patients with essential hypertension. Clin Sci 1982;63(suppl):399-402S.
5. Cappuccio, F.P., Markandu, N.D., Sagnella, G.A., MacGregor, G.A., Sodium restriction lowers high blood pressure through a decreased response of the renin system—direct evidence using saralasin. J Hypertension 1985;3:243-7.
6. Ondetti, M.A., Rubin, B., Cushman, D.W., Design of specific inhibitors of angiotensin-converting enzyme: new class of orally active antihypertensive agents. Science 1977;196:441-4.
7. Hofbauer, K.G., Fuhrer, W., Heusser C.H., Wood, J.M., Comparison of different drug interference with the renin-angiotensin system. J Cardiovasc Pharmacol 1985;7(suppl):62-85.
8. Case, D.B., Atlas, S.A., Laragh, J.H., Position paper: physiologic ‘effects and diagnostic relevance of acute converting enzyme blockade. In: Laragh, J.H., Buhler, F.R., Seldin, D.W., eds. Frontiers in hypertension research. New York: Springer-Verlag, 1981:541-50.
9. MacGregor, G.A., Markandu, N.D., Roulston, J.E., Jones, J.C., Essential hypertension: effect of an oral inhibitor of angiotensin-converting enzyme. Br Med J 1979;ii: 1106–9.
10. George, C.F., Lewis, P.J., Petrie A. Clinical experience with use of ultrasound sphygmomanometer. Br Heart J 1975;37:804-7.
11. Gill, J.S., Zezulka, A.V., Beevers, D.G., Davies P. Relation between initial blood pressure and its fall with treatment. Lancet 1985;i:567-9.
12. MacGregor, G.A., Sagnella, G.A., Macrae, K.D., Misleading paper about misleading statistics. Lancet 1985;i:926-7.
13. MacGregor, G.A., Markandu, N.D., Best, F.E., et al. Double-blind randomised crossover trial of moderate sodium restriction in essential hypertension. Lancet 1982;i:351-5.
14. Richards, A.M., Espiner, E.A., Maslowski, A.H., et al. Blood pressure response to moderate sodium restriction and potassium supplementation in mild essential hypertension. Lancet 1984;i: 757–61.
15. Watt, G.C.M., Edwards, C., Hart, J.T., Hart, M., Walton, P., Foy, C.J.W., Dietary sodium restriction for mild hypertension in general practice. Br Med J 1983;286:432-6.
16. MacGregor, G.A., Markandu, N.D., Banks, R.A., Bayliss, J., Roulston, J.E., Jones, J.C., Captopril in essential hypertension; contrasting effects of adding hydrochlorothiazide or propranolol. Br Med J 1982;284:693-6.
17. Weinberger, M.H., Blood pressure and metabolic responses to hydrochlorothiazide, captopril, and the combination in black and white mild-to-moderate hypertensive patients. J Cardiovasc Pharmacol 1985;7(suppl):52-55.
18. Thaler, B.I., Paulin, J.M., Phelan, E.L., Simpson, F.O., A pilot study to test the feasibility of salt restriction in a community. N Z Med J 1982;95:839-42.
19. Beauchamp, G.K., Bertino, M., Engelman K. Modification of salt taste. Ann Intern Med 1983;98: 763–9.