Changes in the factor VIII complex in diabetic ketoacidosis: evidence of endothelial cell damage?

Diabetologia

Volumn 30, Issue 3, 1987, Pages 160-165

  Greaves, M ^a   Pickering, C ^a   Knight, G ^a   Boulton, A J M ^a   Ball, J ^a   Ward, J D ^a   Preston, F E ^a  

^a ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

Author keywords

Diabetes mellitus; endothelial damage; factor VIII; factor VIII multimers; ketoacidosis

Indexed keywords

BLOOD CLOTTING FACTOR 8; VON WILLEBRAND FACTOR;

BLOOD AND HEMOPOIETIC SYSTEM; CLINICAL ARTICLE; DIABETES MELLITUS; DIABETIC KETOACIDOSIS; DIAGNOSIS; ENDOCRINE SYSTEM; ENDOTHELIUM CELL; ETIOLOGY; HUMAN; HUMAN EXPERIMENT; PERIPHERAL VASCULAR SYSTEM; PRIORITY JOURNAL;

ADULT; ANTIGENS; DIABETIC KETOACIDOSIS; ENDOTHELIUM; FACTOR VIII; HUMANS; MIDDLE AGED; VON WILLEBRAND FACTOR;

EID: 0023091242     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/BF00274221     Document Type: Article

References (33)

1. Platelet hyperaggregation and increased plasma levels of von Willebrand factor in diabetics with retinopathy
2. Elevated factor VIII activity and factor VIII-related antigen in diabetic children without vascular disease
3. Platelets, coagulation and fibrinolysis in patients with diabetic retinopathy
4. Plasma co-factors of platelet function: correlation with diabetic retinopathy and hemoglobins A1a–c
5. Haemostatic variables associated with diabetes and its complications
6. Changes of platelet function and blood clotting in diabetes mellitus
7. Effect of metabolic control with insulin on plasma von Willebrand factor activity (VIII R/vWF) in diabetes mellitus
8. Increased von Willebrand factor in diabetes mellitus
9. Increased activity of “anti-Willebrand factor” in diabetic plasma
10. Increased von Willebrand antihemophilic factor A in diabetic retinopathy
11. Evidence for functional endothelial cell damage in early diabetic retinopathy
12. Plasma levels of beta-thromboglobulin and factor VIII-related antigen in diabetic children and adults
13. Tests for platelet changes, acute phase reactants and serum lipids in diabetes mellitus and peripheral vascular disease
14. Factor-VIII complex and endothelial damage
15. Altered factor VIII complexes in patients with acute respiratory insufficiency
16. Altered factor VIII in acute respiratory failure
17. The assay of antihaemophilic globulin activity
18. Assay of ristocetin co-factor using fixed platelets and a platelet counting technique
19. Antigen-antibody crossed electrophoresis
20. Factor VIII related antigen: an improved enzyme immunoassay
21. Use of N-bromosuccinimide for the iodination of proteins for radioimmunoassay
22. The complex multimeric composition of factor VIII/von Willebrand factor
23. Analysis of the complexity of the multimeric structure of factor VIII related antigen/von Willebrand protein using a modified electrophoretic technique
24. Haemostatic changes in diabetic coma
25. Physiological mechanisms in coagulation and fibrinolysis
26. Possible evidence for an increased factor VIII antigen synthesis in vascular endothelium of diabetic subjects
27. Cerebral intravascular coagulation in diabetic ketoacidosis
28. Elevation of factor VIII coagulant activity over factor VIII coagulant antigen in diabetic children without vascular disease. A sign of activation of the factor VIII coagulant moiety during poor diabetes control
29. Factor VIII-related antigen (VIII RAg) in haemophilic patients and in carriers
30. Factor VIII-related antigen pre-peak on crossed immunoelectrophoresis: A non-random phenomenon
31. Factor VIII antigen pre-peak
32. Factor VIII antigen pre-peak