A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice

Nature

Volumn 326, Issue 6110, 1987, Pages 295-298

  Kuehn, Michael R ^a   Bradley, Allan ^a   Robertson, Elizabeth J ^a   Evans, Martin J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; CONGENITAL DISORDER; CYTOLOGY; EMBRYO; EMBRYO CULTURE; ENZYME DEFICIENCY; ETIOLOGY; GENETIC ENGINEERING; HEREDITY; LESCH NYHAN SYNDROME; MOUSE; NERVOUS SYSTEM; NONHUMAN; PRIORITY JOURNAL;

ANIMAL; BLASTOCYST; CHIMERA; DISEASE MODELS, ANIMAL; DNA RESTRICTION ENZYMES; GENES, STRUCTURAL; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LESCH-NYHAN SYNDROME; MICE; STEM CELLS; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023090920     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/326295a0     Document Type: Article

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