Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene

Nature

Volumn 324, Issue 6092, 1986, Pages 34-38

  Thomas, Kirk R ^a   Capecchi, Mario R ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY - DNA SEQUENCES; GENETIC ENGINEERING; MUTAGENESIS;

GENE TARGETING; HETERODUPLEX-INDUCED MUTAGENESIS; HOMOLOGOUS RECOMBINATION;

BIOLOGICAL MATERIALS;

DNA;

GENETIC ENGINEERING; HEREDITY; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ANIMAL; CELL LINE; DNA, RECOMBINANT; DRUG RESISTANCE, MICROBIAL; FIBROBLASTS; MICE; MODELS, GENETIC; MUTATION; NEOMYCIN; PLASMIDS; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSFECTION; TRANSLATION, GENETIC;

EID: 0023043553     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/324034a0     Document Type: Article

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