The design and production of semisynthetic ribonucleases with increased thermostability by incorporation of S‐peptide analogues with enhanced helical stability

Proteins: Structure, Function, and Bioinformatics

Volumn 1, Issue 1, 1986, Pages 23-33

  Mitchinson, Colin ^a,b   Baldwin, Robert L ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b GENENTECH INC   (United States)

Author keywords

framework model of folding; peptide helix; protein stability

Indexed keywords

C PEPTIDE; RIBONUCLEASE;

ANIMAL CELL; CATTLE; NONHUMAN; PANCREAS;

AMINO ACID SEQUENCE; KINETICS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN CONFORMATION; RIBONUCLEASES; SUPPORT, U.S. GOV'T, NON-P.H.S.; TEMPERATURE;

EID: 0023036230     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.340010106     Document Type: Article

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