An In vitro skin corrosivity test-Modifications and validation

Food and Chemical Toxicology

Volumn 24, Issue 6-7, 1986, Pages 507-512

  Oliver, G J A ^a   Pemberton, M A ^a   Rhodes, C ^a  

^a AKZO NOBEL CENTRAL RESEARCH   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; EPIDERMIS; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN; SKIN IRRITATION;

ANIMAL; DOUBLE-BLIND METHOD; ELECTRIC CONDUCTIVITY; FALSE POSITIVE REACTIONS; IN VITRO; IRRITANTS; RATS; RATS, INBRED STRAINS; SKIN;

EID: 0023031903     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/0278-6915(86)90102-X     Document Type: Article

References (13)

1. Describing the validity of carcinogen screening tests
2. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes
3. Skin permeability theory in relation to measurements of percutaneous absorption in toxicology
4. Hazardous substances
5. Acute dermal irritation/corrosion
6. An in vitro model for assessing the corrosive potential of chemicals to the skin
7. Prediction of skin corrosive potential in vitro
8. An in vitro epidermal slice technique for identifying chemicals with potential for severe cutaneous effects
9. The identification of corrosive agents for human skin in vitro
10. Relevance of in vitro tests to in vivo acute skin inflammation: potential in vitro applications of skin keratome slices, neutrophils, fibroblasts, mast cells and macrophages
11. Transport of dangerous goods
12. Absorption through human and laboratory animal skins; in vitro comparisons