Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism

Journal of Biological Chemistry

Volumn 261, Issue 11, 1986, Pages 5051-5060

  Guengerich, F P ^a   Martin, M V ^a   Beaune, P H ^a   Kremers, P ^b   Wolff, T ^b   Waxman, D J ^b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AROCLOR 1254; BETA NAPHTHOFLAVONE; CYTOCHROME P450; DEXAMETHASONE; ISOSAFROLE; LIVER ENZYME; MONOCLONAL ANTIBODY; NIFEDIPINE; PHENOBARBITAL;

ANIMAL CELL; DRUG METABOLISM; HUMAN; HUMAN CELL; LIVER; MICROSOME; PHARMACOKINETICS; PRIORITY JOURNAL; RAT;

ANIMALS; CYTOCHROME B GROUP; CYTOCHROME P-450 ENZYME SYSTEM; CYTOCHROMES B5; FEMALE; HUMANS; IMMUNOLOGIC TECHNIQUES; MALE; MICROSOMES, LIVER; NIFEDIPINE; OXIDATION-REDUCTION; PHARMACEUTICAL PREPARATIONS; POLYMORPHISM, GENETIC; RATS;

ANIMALIA;

EID: 0022998708     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)