Intraoperative Probe-Directed Immunodetection Using a Monoclonal Antibody

Archives of Surgery

Volumn 121, Issue 12, 1986, Pages 1391-1394

  O'dwyer, Patrick J ^a   Mojzisik, Cathy M ^a   Hinkle, George H ^a   Rousseau, Michel ^a   Olsen, John ^a   Tuttle, Steven E ^a   Barth, Rolf F ^a   Thurston, Marlin O ^a   McCabe, Daniel P ^a   Farrar, William B ^a   Martin, Edward W ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY I 125; MONOCLONAL ANTIBODY; RADIOISOTOPE; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL ARTICLE; COLORECTAL CANCER; DIAGNOSIS; GAMMA COUNTING; HUMAN; LARGE INTESTINE; PRIORITY JOURNAL; TUMOR LOCALIZATION;

ADULT; ANIMALS; ANTIBODIES, MONOCLONAL; COLONIC NEOPLASMS; EVALUATION STUDIES; FEMALE; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; INTRAOPERATIVE CARE; IODINE RADIOISOTOPES; MALE; MICE; MICE, NUDE; MIDDLE AGED; RECTAL NEOPLASMS; SCINTILLATION COUNTING;

EID: 0022993644     PISSN: 00040010     EISSN: 15383644     Source Type: Journal    
DOI: 10.1001/archsurg.1986.01400120037005     Document Type: Article

References (16)

1. Goldenberg DM, Deland F, Kim E, et al: Use of radiolabeled antibodies to carcinoembryonic antigen for the detection and localization of diverse cancers by external photoscanning. N Engl J Med 1978;298:1384-1388.
2. Goldenberg DM, Kim EE, Bennett SJ, Nelson MO, et al: Carcinoembryonic antigen radioimmunodetection in the evaluation of colorectal cancer and in the detection of occult neoplasms. Gastroenterology 1983;84:524-532.
3. Dykes PW, Hine KR, Bradwell AR, et al: Localisation of tumor deposits by external scanning after injection of radiolabeled anti-carcinoembryonic antigen. Br Med J 1980;280:220-222.
4. Sullivan DC, Silva JS, Cox CE, et al: Localization of I-131–labeled goat and primate anti—carcinoembryonic antigen (CEA) antibodies in patients with cancer. Invest Radiol 1982;17:350-355.
5. Mach J-P, Carrel S, Forni M, et al: Tumor localization of radiolabeled antibodies against carcinoembryonic antigen in patient with carcinoma. N Engl J Med 1980;303:5-10.
6. Mach J-P, Chatal J-F, Lumbroso J-D, et al: Tumor localization in patients by radiolabeled monoclonal antibodies against colon carcinoma. Cancer Res 1983;43:5593-5600.
7. Chatal J-F, Douillard J-Y, Saccavini J-C, et al: Clinical prospective study with radioiodinated monoclonal antibodies directed against colorectal cancer, in Baldwin RW, Byers VS (eds): Monoclonal Antibodies for Cancer Detection and Therapy. Orlando, Fla, Academic Press Inc, 1985, pp 159-180.
8. Rockoff SD, Goodenough DJ, McIntire KR: Theoretical limitations in the immunodiagnostic imaging of cancer with computed tomography and nuclear scanning. Cancer Res 1980;40:3054-3058.
9. Aitken DR, Hinkle GH, Thurston MO, et al: A gamma-detecting probe for radioimmune detection of CEA-producing tumors. Dis Colon Rectum 1984;27:279-282.
10. Martin DT, Hinkle GH, Tuttle S, et al: Intraoperative radioimmunodetection of colorectal tumor with a hand-held radiation detector. Am J Surg 1985;150:672-675.
11. Herlyn M, Steplewski Z, Herlyn D, et al: Colorectal carcinoma specific antigen: Detection by means of monoclonal antibodies. Proc Natl Acad Sci USA 1979;76:1438-1442.
12. Martin Jr. EW, Tuttle SE, Rousseau M, et al: Radioimmunoguided surgery: Intraoperative use of monoclonal antibody 17-1A in colorectal cancer. Hybridoma, in press.
13. Mach J-P, Buchegger F, Grob J-PQ, et al: Improvement of colon carcinoma imaging: Polyclonal anti-CEA antibodies and static photoscanning to monoclonal Fab fragments and ECT, in Baldwin RW, Byers VS (eds): Monoclonal Antibodies for Cancer Detection and Therapy. Orlando, Fla, Academic Press Inc, 1985, pp 53-64.
14. Harwood PJ, Boden J, Pedley RB, et al: Comparative tumor localization of antibody fragments and intact IgG in nude mice bearing a CEA-producing human colon tumor xenograft. Eur J Cancer Clin Oncol 1985;21: 1515-1522.
15. Hinkle GH, Abdel-Nabi H, Miller EA, et al: Radioimmunodetection of implanted tumors with the gamma probe. NCI Monogr, in press.
16. Rankin EM, McVie JG: Radioimmunodetection of cancer: Problems and potential. Br Med J 1983;287:1402-1404.