Hormone‐Like Activity of Human Thrombin

Annals of the New York Academy of Sciences

Volumn 485, Issue 1, 1986, Pages 335-348

  BAR‐SHAVIT, RACHEL ^a   HRUSKA, KEITH A ^a   KAHN, ARNOLD J ^b   WILNER, GEORGE D ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CALCIUM; CELL SURFACE RECEPTOR; GROWTH PROMOTOR; THROMBIN; THROMBIN RECEPTOR;

ARTICLE; CELL LINE; CYTOSKELETON; HUMAN; MACROPHAGE; MONOCYTE; NEUTROPHIL CHEMOTAXIS; PHYSIOLOGY; STRUCTURE ACTIVITY RELATION; ACTIN POLYMERIZATION; CELL STRAIN HL 60; CHEMOTAXIS; DNA SYNTHESIS; DRUG ANALYSIS; DRUG COMPARISON; DRUG DETERMINATION; DRUG MECHANISM; DRUG TISSUE LEVEL; HISTOLOGY; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; REVIEW;

ACTINS; CALCIUM; CELL LINE; CHEMOTAXIS, LEUKOCYTE; CYTOSKELETON; GROWTH SUBSTANCES; HUMAN; MACROPHAGES; MONOCYTES; RECEPTORS, CELL SURFACE; RECEPTORS, THROMBIN; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; THROMBIN;

EID: 0022924098     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1986.tb34595.x     Document Type: Article

References (34)

1. Monocyte chemotaxis: stimulation by specific exosite region in thrombin.
2. Protease mitogenic response of chick embryo fibroblasts and receptor binding/processing of human a‐thrombin.
3. Stimulation of endothelial cell prostacycline production by thrombin, trypsin, and ionophore A23187.
4. Platelet stimulation by thrombin and other proteases.
5. Thrombin chemotactic domain is localized within a B chain CNBr fragment.
6. Identification of a thrombin sequence with growth factor activity on macrophages.
7. Chemotactic responses of monocytes to thrombin.
8. Receptor‐mediated chemotactic response of a macrophage cell line (J‐774) to thrombin.
9. Regulation of normal differentiation in mouse and human myeloid leukemia cells by phorbol esters and the mechanism of tumor promotion.
10. Induction of monocyte differentiation and bone resorption by 1,25‐dihydroxyvitamin D3.
11. Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.
12. Induction of differentiation of cultured human promyelocytic leukemia cells by retinoids.
13. Differentiation of a human leukemia cell line and expression of collagenase inhibitor.
14. Human thrombins: production, evaluation and properties of a‐thrombin.
15. The primary structure of human prethrombin 2 and a‐thrombin.
16. The reaction of aldolase with 2‐methylmaleic acid.
17. Analytical peptide mapping by high performance liquid chromatography: application to intestinal Ca‐binding proteins.
18. Stimulation by chemotactic factor of actin association with the cytoskeleton in rabbit neutrophils.
19. Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new intracellulary fluorescent indicator.
20. Immunochemical studies of human fibrinopeptide A using synthetic peptide homologues.
21. Immunochemical analysis of rabbit antihuman fibrinopeptide B antibodies.
22. S2 deprotection of synthetic peptides with a low concentration of HF in dimethyl sulfide: evidence and application in peptide synthesis.
23. Characterization of the complementary deoxyribonucleic acid and gene coding for human proombin.
24. Computer‐generated models of blood coagulation factor Xa, factor IXa, and thrombin, based upon structural homology to other serine proteases.
25. Intracellular calcium redistribution and its relationship to fMet‐Leu‐Phe, leukotriene B4, and phorbol ester‐induced rabbit neutrophil degranulation.
26. Ionic events in neutrophil chemotaxis and secretion.
27. Thrombin‐mediated chemotaxis. Relationship of ligand structure to biological activity.
28. The turnover of thrombin:thrombomodulin complex in cultured human umbilical cells and A549 lung cancer cells: endocytosis and degradation of thrombin.
29. Protease nexin: a cellular component that links thrombin and plasminogen activator and mediates their binding to cells.
30. The active site of antithrombin: release of the same proteolytically cleaved form of the inhibitor from complexes with factor IXa, Xa, and thrombin.
31. Heparin cofactor II.