Are sulfhydryl groups essential for function of the glutamate-operated receptor-ionophore complex?

Neuroscience Letters

Volumn 66, Issue 3, 1986, Pages 305-310

  Kiskin, N I ^a   Krishtal, O A ^a   Tsyndrenko, A Ya ^a   Akaike, N ^a  

^a BOGOMOLETZ INSTITUTE OF PHYSIOLOGY   (Ukraine)

Author keywords

intracellular perfusion; kainic acid chemical modification; l glutamate; rat hippocampal pyramidal neuron; sulfhydryl residue

Indexed keywords

4 CHLOROMERCURIBENZOIC ACID; 5,5' DITHIOBIS(2 NITROBENZOIC ACID); CADMIUM CHLORIDE; GLUTAMATE RECEPTOR; GLUTAMIC ACID; KAINIC ACID; MERCURIC CHLORIDE; N ETHYLMALEIMIDE; THIOL GROUP; ZINC CHLORIDE;

ANIMAL CELL; CENTRAL NERVOUS SYSTEM; DOSE RESPONSE; DRUG EFFICACY; DRUG INTERACTION; DRUG RECEPTOR BINDING; DRUG RESPONSE; HIPPOCAMPUS; NERVE CELL MEMBRANE POTENTIAL; NERVOUS SYSTEM; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; TOPICAL DRUG ADMINISTRATION;

ANIMAL; CYSTEINE; HIPPOCAMPUS; ION CHANNELS; IONOPHORES; KAINIC ACID; MEMBRANE POTENTIALS; MERCURIC CHLORIDE; NEURONS; RATS; RECEPTORS, GLUTAMATE; RECEPTORS, NEUROTRANSMITTER; SULFHYDRYL COMPOUNDS; SUPPORT, NON-U.S. GOV'T;

EID: 0022922466     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(86)90036-4     Document Type: Article

References (13)

1. Studies on the nature of the cholinergic receptor
2. Biochemical studies of nerve excitability: the use of protein modifying reagents for characterizing sites involved in nerve excitation
3. Effects of the electrophoretic application of sulfhydryl reagents to the endplate receptors
4. Excitatory amino acid receptors in hippocampal neurones: kainate fails to desensitize them
5. Receptor for ATP in the membrane of mammalian sensory neurones
6. Some metal complexes of sulfur-containing amino acids
7. Drug Biotransformation
8. Disulfide bonds in nicotinic receptors
9. The effect of disulfide bond reduction on the properties of cholinergic receptors in the chick muscle
10. Effect of glutathione depletion on tissue deposition of methylmercury in rats
11. Association constants of methylmercury with sulfhydryl and other bases