Focal injection of 2-amino-7-phosphonoheptanoic acid into prepiriform cortex protects against pilocarpine-induced limbic seizures in rats

Neuroscience Letters

Volumn 70, Issue 1, 1986, Pages 69-74

  Millan, M H ^a   Patel, S ^a   Mello, L M ^a   Meldrum, B S ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

2 Amino 7 phosphonoheptanoic acid; Diffusion study; Limbic seizure Anticonvulsant; Pilocarpine; Prepiriform cortex; Rat

Indexed keywords

2 AMINO 7 PHOSPHONOHEPTANOIC ACID; ANTICONVULSIVE AGENT; PILOCARPINE; RADIOISOTOPE;

2 AMINO 7 PHOSPHONOHEPTANOIC ACID H 3; ANIMAL MODEL; CENTRAL NERVOUS SYSTEM; COMPLEX PARTIAL SEIZURE; CONVULSION; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; INTOXICATION; INTRACEREBRAL DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; NERVOUS SYSTEM; NEUROTOXICITY; NONHUMAN; PHARMACOKINETICS; PREPIRIFORM CORTEX; PRIORITY JOURNAL; RAT;

AMINO ACIDS; ANIMAL; ANTICONVULSANTS; CONVULSIONS; LIMBIC SYSTEM; MALE; PILOCARPINE; RATS; RATS, INBRED STRAINS; SUPPORT, NON-U.S. GOV'T;

EID: 0022921075     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(86)90439-8     Document Type: Article

References (8)

1. Evidence of a neurotransmitter role for aspartate and γ-aminobutyric acid in the rat olfactory cortex
2. Effect of chronic bulbectomy on the depth distribution of amino acid transmitter candidates in rat olfactory cortex
3. The Rat Brain
4. 2-amino-7-phosphonoheptanoic acid (2-APH) infusion into entopeduncular nucleus protects against limbic seizures in rats
5. A crucial epileptogenic site in the deep prepiriform cortex
6. Intracerebral site of convulsant action of bicuculline
7. The differential projections of the olfactory bulb and accessory olfactory bulb in mammals
8. Excitatory neurotransmission within substantia nigra pars reticulata regulates threshold for seizures produced by pilocarpine in rats: effects of intranigral 2-amino-7-phosphonoheptanoate and N-methyl-d-aspartate