Alpha-thalassemia in Papua New Guinea

Human Genetics

Volumn 74, Issue 4, 1986, Pages 432-437

  Yenchitsomanus, P ^a   Summers, K M ^a   Board, P G ^a   Bhatia, K K ^b   Jones, G L ^c   Johnston, K ^d   Nurse, G T ^d  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^b PAPUA NEW GUINEA INSTITUTE OF MEDICAL RESEARCH   (Papua New Guinea)

^c UNIVERSITY OF NEW ENGLAND   (Australia)

^d Blood Transfusion Service Papua New Guinea Red Cross ^*  (Papua New Guinea)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA THALASSEMIA; BLOOD AND HEMOPOIETIC SYSTEM; CLINICAL ARTICLE; CONGENITAL DISORDER; EPIDEMIOLOGY; GENE DELETION; GEOGRAPHIC DISTRIBUTION; HEREDITY; HUMAN; PAPUA NEW GUINEA; PRIORITY JOURNAL;

CHROMOSOME DELETION; GLOBINS; HUMANS; LINKAGE (GENETICS); PAPUA NEW GUINEA; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; THALASSEMIA;

EID: 0022919087     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/BF00280500     Document Type: Article

References (38)

1. Homozygous Hb J Tongariki: evidence for only one alpha chain structural locus in Melanesians
2. Papua New Guinea: human geography
3. Haematology in PNG revisited
4. Hereditary ovalocytosis in Melanesians
5. The occurrence of haemoglobin-J (Tongariki) and of thalassaemia on Karkar Island and the Papua New Guinea mainland
6. Haemoglobin H in a Papuan family
7. Selective depression of blood group antigens associated with hereditary ovalocytosis among Melanesians
8. Malaria and filariasis in the Ok Tedi region of the Star Mountains, Papua New Guinea
9. The epidemiology of malaria in a population surrounding Madang, Papua New Guinea
10. Distribution pattern, population genetics and anthropological significance of thalassemia and abnormal hemoglobin in Melanesia
11. Acute malaria in children in Madang: endemicity, clinical presentation and treatment
12. Two different molecular organizations account for the single α-globin gene of α-thalassemia-2 genotype
13. Oxidant damage mediates variant red cell resistance to malaria
14. Haemoglobin J Tongariki (α115 alanine→aspartic acid): the first new haemoglobin variant found in a Pacific (Melanesian) population
15. Distribution of β-thalassemia trait and erythrocyte glucose-6-phosphate dehydrogenase deficiency in the Markham River Valley of New Guinea
16. Triplicated α-globin loci in humans
17. Carrier detection of hemophilia B by using a restriction site polymorphism associated with the coagulation factor IX gene
18. Alpha-thalassemia
19. A novel α-globin gene arrangement in man
20. Independent recombination events between the duplicated human α-globin genes; implications for their concerted evolution
21. Melanesians and Polynesians share a unique α-thalassemia mutation
22. The occurrence of haemoglobin-J (Tongariki) and the beta-thalassemia trait on Kar Kar Island and the mainland of Papua New Guinea
23. Ovalocytic erythrocytes from Melanesians are resistant to invasion by malaria parasites in culture
24. Language, genes and people in the Pacific
25. The chromosomal arrangement of human α-like globin genes: sequence homology and α-globin gene deletions
26. Boundaries of gene conversion within the duplicated human α-globin genes: concerted evolution by segmental recombination
27. α-Thalassemia in Papua New Guinea
28. Gene deletions in α thalassemia prove that the 5′ ξ locus is functional
29. Haemoglobin H disease in a Papuan
30. Malaria and hereditary ovalocytosis
31. Is the doubly deleted α-thalassemia gene a “fugitive” allele?
32. The molecular basis of α-thalassemia in Thailand
33. Linguistic prehistory in New Guinea area
34. Extremely high frequencies of α-globin gene deletion in Madang and on Kar Kar Island, Papua New Guinea
35. A single α-globin gene deletion in Australian Aborigines
36. Characterisation of G6PD deficiency and thalassemia in Papua New Guinea