Mutagenic sterol hydroperoxides

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 161, Issue 1, 1986, Pages 39-48

  Smith, Leland L ^a   Smart, Vera B ^a   Made Gowda, N M ^a  

^a Medical Branch   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; S 9; SUPEROXIDE DISMUTASE;

5ALPHA HYDROPEROXYCHOLEST 6 EN 3BETA OL; 7ALPHA HYDROPEROXYCHOLESTEROL; ETIOLOGY; HEREDITY; METABOLIC ACTIVATION; MUTAGENICITY; NONHUMAN; SALMONELLA TYPHIMURIUM; STEROL HYDROPEROXIDE;

ANIMAL; BIOTRANSFORMATION; CATALASE; CHOLESTEROL; COMPARATIVE STUDY; KINETICS; MALE; MICROSOMES, LIVER; MUTAGENICITY TESTS; MUTAGENS; MUTATION; RATS; RATS, INBRED STRAINS; SALMONELLA TYPHIMURIUM; STRUCTURE-ACTIVITY RELATIONSHIP; SUPEROXIDE DISMUTASE; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0022915418     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/0027-5107(86)90098-9     Document Type: Article

References (45)

1. Methods of detecting carcinogens and mutagens wiht the Salmonella/mammalian-microsome mutagenicity test
2. High-performance liquid chromatography of cholesterol autoxidation products
3. Further investigations of mutagenic cholesterol preparations
4. The mechanism of the rearrangement of linoleate hydroperoxides
5. Mutagenicity of quinones: Pathways of metabolic activation and detoxification
6. Positive control of a regulon for defense against oxidative stress and some heat-shock proteins in Salmonella typhimurium
7. Mutagenicity testing with TA97 and TA102 of 30 DNA-damaging compounds, negative with other Salmonella strains
8. Negative Ames test of epoxide fatty methyl esters derived from both homolysis of linoleitic acid hydroperoxides
9. Site-specific cleavage of double-strand DNA by hydroperoxide of linoleic acid
10. Chemical aspects of the mutagenic activity of the ascorbic acid autoxidation system
11. Transformation of hamster embryo cells by cholesterol α-epoxide and lithocholic acid
12. Transformation of hamster embryo cells by neutral sterols and bile acids
13. Microbial hydroxylations, IX. On the dihydroxylation of 19-norsteroids by Curvularia lunata
14. A new Salmonella tester strain (TA102) with A-T base pairs at the site of mutation detects oxidative mutagens
15. On reaction of sterol hydroperoxides with superoxide
16. Revised methods for the Salmonella mutagenicity test
17. Reduced mutant yield at high doses in the Salmonella/activation assay: The cause is not always toxicity
18. Microbial assays for mutagenicity A modified liquid culture method compared with the agar plate system for precision and sensitivity
19. Forward mutation in Escheria coli and gene conversion in Saccharomyces cerevisiae compared quantitatively with reversion in Salmonella typhimurium
20. Mutagenicity of oxygen free radicals
21. DNA strand breakage in vitro by autoxidized unsaturated fatty acids
22. Chromosome damage and DNA repair induced in human fibroblasts by UV and cholesterol oxide
23. Mutagens in nipple aspirates of breast fluid
24. Oxidative mutagens specific for A-T base pairs induce forward mutations to l-arabinose resistance in Salmonella typhimurium
25. 6-Steroid-5α-Hydroperoxyden
26. Microbiological studies investigating mutagenicity of deep frying fractions and some of their compounds
27. Cholesterol expoxide is a direct-acting mutagen
28. Metabolic transformations, Biological effects
29. Detection of sterol hydroperoxides on thin-layer chromatoplates by means of the Wurster dyes
30. Thin-layer chromatographic examination of cholesterol autoxidation
31. Mutagenic cholesterol preparations
32. Steroid metabolism, XLVII. Oxidized cholesterol esters in human tissues
33. Lipid peroxidations of cholesterol
34. Biological conversion of 17α-hydroperoxyprogesterone to 11α-dihydroxyprogesterone
35. Mutagenic effect of 7,12-dimethylbenz[a]anthracene-epidioxide on Salmonella typhimurium
36. 2 by catalase induction in Salmonella typhimurium
37. Screening methods using microbes for the environmental carcinogens
38. Mutagenicities of N-nitrosamines on Salmonella
39. Activation with catalase of mutagenicity of hydroperoxides of some fatty acids and hydrocarbons
40. Mutagenicity of low molecular substancese in various superoxide generating systems
41. Mutagenicity of and formation of oxygen radicals by trioses and glyoxal derivatives
42. Mutagenic activity of autoxidized linolenic and linoleic acid
43. Mutagenicity of hydroperoxides of fatty acids and some hydrocarbons
44. Desmutagenic activity of peroxidase on autoxidized linolenic acid
45. Synthesis and properties of two new steroid hydroperoxides: An alternative pathway for the formation of 6β-hydroxyprogesterone